Podcast
Questions and Answers
Which type of carbohydrates is considered the most cariogenic?
Which type of carbohydrates is considered the most cariogenic?
What role do lactobacilli play in dental caries?
What role do lactobacilli play in dental caries?
Which of the following factors makes sucrose particularly cariogenic?
Which of the following factors makes sucrose particularly cariogenic?
What is the primary component produced by cariogenic bacteria during the breakdown of sucrose?
What is the primary component produced by cariogenic bacteria during the breakdown of sucrose?
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Why are polysaccharides less cariogenic compared to disaccharides?
Why are polysaccharides less cariogenic compared to disaccharides?
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Which bacterium is primarily associated with the production of dental plaque due to sucrose metabolism?
Which bacterium is primarily associated with the production of dental plaque due to sucrose metabolism?
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What happens during the hydrolysis of sucrose?
What happens during the hydrolysis of sucrose?
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Which of the following statements about the cariogenicity of carbohydrates is true?
Which of the following statements about the cariogenicity of carbohydrates is true?
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How does an increase in the amount of carbohydrate intake affect caries activity?
How does an increase in the amount of carbohydrate intake affect caries activity?
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Which factor contributes most to increased caries susceptibility from carbohydrate intake?
Which factor contributes most to increased caries susceptibility from carbohydrate intake?
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What characteristic of sticky carbohydrates contributes to their cariogenicity?
What characteristic of sticky carbohydrates contributes to their cariogenicity?
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What is true about refined carbohydrates concerning their effect on dental health?
What is true about refined carbohydrates concerning their effect on dental health?
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Which carbohydrate is considered non-cariogenic despite being refined?
Which carbohydrate is considered non-cariogenic despite being refined?
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In the Vipeholm Experiment, what was one significant finding regarding sticky carbohydrates?
In the Vipeholm Experiment, what was one significant finding regarding sticky carbohydrates?
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What happens to the pH level in the mouth after consuming carbohydrates?
What happens to the pH level in the mouth after consuming carbohydrates?
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Which of the following is NOT a reason why frequent carbohydrate intake increases caries risk?
Which of the following is NOT a reason why frequent carbohydrate intake increases caries risk?
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What happens when demineralization periods exceed remineralization periods?
What happens when demineralization periods exceed remineralization periods?
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Which type of tooth morphology is more susceptible to caries?
Which type of tooth morphology is more susceptible to caries?
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Which of the following factors is least significant in the initiation of caries?
Which of the following factors is least significant in the initiation of caries?
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What is the role of fluoride in dental health?
What is the role of fluoride in dental health?
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Which condition makes newly erupted teeth more susceptible to caries?
Which condition makes newly erupted teeth more susceptible to caries?
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What type of fissures are generally more caries resistant?
What type of fissures are generally more caries resistant?
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How can fluoride aid in increasing enamel resistance to acids?
How can fluoride aid in increasing enamel resistance to acids?
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Which of the following is an environmental factor affecting caries development?
Which of the following is an environmental factor affecting caries development?
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What characteristic of the early enamel lesion is described by its cone shape?
What characteristic of the early enamel lesion is described by its cone shape?
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Which zone of the early smooth surface enamel caries represents initial demineralization?
Which zone of the early smooth surface enamel caries represents initial demineralization?
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What do submicroscopic pores in the enamel account for, in terms of total enamel volume?
What do submicroscopic pores in the enamel account for, in terms of total enamel volume?
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What causes the dark appearance of the dark zone when viewed by transmitted light?
What causes the dark appearance of the dark zone when viewed by transmitted light?
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Which method is used to determine the percentage of enamel pores by volume?
Which method is used to determine the percentage of enamel pores by volume?
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What is the consequence of the structural features being lost in the translucent zone?
What is the consequence of the structural features being lost in the translucent zone?
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In microradiography, how are differences in the amount and distribution of minerals reflected?
In microradiography, how are differences in the amount and distribution of minerals reflected?
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What is believed to cause the smaller pores in the dark zone?
What is believed to cause the smaller pores in the dark zone?
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What distinguishes infected dentinal lesions from uninfected dentinal lesions?
What distinguishes infected dentinal lesions from uninfected dentinal lesions?
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Which zone is not associated with uninfected dentinal lesions?
Which zone is not associated with uninfected dentinal lesions?
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What is the primary cause of root surface caries?
What is the primary cause of root surface caries?
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Which reactionary change in dentin occurs due to severe stimuli?
Which reactionary change in dentin occurs due to severe stimuli?
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What characterizes tubular sclerosis in dentin?
What characterizes tubular sclerosis in dentin?
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What is a characteristic feature of regular reactionary dentin?
What is a characteristic feature of regular reactionary dentin?
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Which of the following zones is primarily associated with affected dentinal lesions?
Which of the following zones is primarily associated with affected dentinal lesions?
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Which statement accurately describes bacteria's role in root surface caries?
Which statement accurately describes bacteria's role in root surface caries?
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What occurs during the phase of bacterial invasion in enamel caries?
What occurs during the phase of bacterial invasion in enamel caries?
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What is the primary result of the destruction phase in enamel caries?
What is the primary result of the destruction phase in enamel caries?
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What happens to enamel when acids reach the dentino-enamel junction (DEJ)?
What happens to enamel when acids reach the dentino-enamel junction (DEJ)?
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What characterizes an uninfected dentinal lesion during early caries development?
What characterizes an uninfected dentinal lesion during early caries development?
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What is observed in the zone of hypermineralization in dentinal lesions?
What is observed in the zone of hypermineralization in dentinal lesions?
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Which component forms the bulk of the dentin matrix?
Which component forms the bulk of the dentin matrix?
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What occurs in the zone of fatty degeneration during dentinal caries?
What occurs in the zone of fatty degeneration during dentinal caries?
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How much of the dentin's composition is made up of organic material?
How much of the dentin's composition is made up of organic material?
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Study Notes
Dental Caries Definition and Etiology
- Dental caries is a progressive microbial disease affecting hard tooth structures.
- It's characterized by demineralization of the inorganic portion and destruction of the organic substance of the tooth.
- Contributing factors to dental caries:
- Cariogenic bacteria (agent)
- Fermentable carbohydrates (substrate)
- Susceptible tooth and saliva (host)
- Time
- Means of microorganism and substrate localization on tooth surfaces (dental plaque).
Role of Bacteria in Dental Caries
- Cariogenic bacteria produce acids from the fermentation of carbohydrates.
- These acids lead to enamel and dentin demineralization.
Experiments Demonstrating the Role of Cariogenic Microorganisms
- Miller's experiment demonstrated that caries-like lesions form in saliva when carbohydrates are added.
- Caries result from carbohydrate fermentation by bacteria in saliva.
- Initial experiment established that bacteria is necessary for caries formation.
- Orland's experiment showed that germ-free animals don't develop caries, concluding bacteria is essential for caries formation.
Production of Gnotobiotes
- Aim: to determine which bacteria produce dental caries.
- Rats were divided into groups and fed specific micro-organisms (streptococci, staphylococci, lactobacilli, etc.).
- Streptococcus mutans produced smooth surface and pit-and-fissure caries.
- Lactobacilli produced pit-and-fissure caries.
- Not all bacteria cause dental caries.
- Streptococcus mutans is more cariogenic than lactobacilli.
Essential Features for Cariogenic Bacteria
- Ability to produce acids (acidogenic).
- Ability to survive in acidic environments (aciduric).
- Synthesis of insoluble extracellular polysaccharides (dextrans and levans).
- Synthesis and utilization of intracellular storage polysaccharides (amylopectin).
- Ability to actively transport fermentable sugars.
- Attachment mechanisms for firm adhesion to tooth surfaces.
Cariogenic Bacteria: Streptococcus Mutans and Lactobacillus Species
- Streptococcus mutans:
- Acidogenic, acid-tolerant.
- Synthesizes extracellular polysaccharides (dextrans and levans) for adhesion.
- Undergoes morphological mutations with changing environmental conditions (pH).
- Lactobacillus species:
- Acidogenic, acid-tolerant.
- Can only produce pit and fissure caries in gnotobiotic animals.
- Do not produce extracellular polysaccharides for adhesion.
Role of Fermentable Carbohydrates
- Types of carbohydrates: monosaccharides (e.g., glucose, fructose), disaccharides (e.g., sucrose, maltose, lactose), and polysaccharides (e.g., starch, glycogen).
- Sucrose is the most cariogenic carbohydrate.
- Sucrose is cheap, highly available, low molecular weight and dissolves easily into dental plaque.
- Bacterial enzymes rapidly break down sucrose producing acids.
- Sucrose with the help of cariogenic bacteria (e.g., Streptococcus mutans) forms extracellular polysaccharides (dextran & levan).
Refinement of Carbohydrate
- Refinement of carbohydrates increase cariogenicity.
- Refinement increases the concentration of fermentable carbohydrates.
- Refinement removes fibrous material increasing adhesiveness.
- Xylitol, a refined carbohydrate, is not cariogenic.
- Honey is cariogenic despite not being refined.
Vipeholm Experiment
- Aim: to determine the effect of the amount, frequency, and texture of carbohydrates on caries susceptibility.
- High caries activity correlated with frequent intake of sticky carbohydrates.
- Caries in groups consuming sugar between meals was less severe than consumption between meals.
3. Dental Plaque
- Definition: a tenacious bacterial structure formed on tooth surfaces.
- Composition: Microorganisms, proteins, carbohydrates, and inorganic content.
- Role of plaque matrix: acts as a diffusion-limiting membrane, slow down saliva action & contributes to adhesiveness.
- Factors affecting formation & thickness: Tooth anatomy, appliances, surface structure, friction, oral hygiene measures, and diet.
Mechanism of Bacterial Plaque Formation
- Formation of an acquired enamel pellicle (acellular).
- Colonization of cell-free pellicle by pioneer bacteria.
- Rapid growth phase of bacteria spreading across the tooth surface.
- Formation of an intermediate/mature community.
- Selective replacement of microbes in the mature community.
Microbial Succession
- Aciduric organisms (e.g., Streptococcus mutans (positive interaction)) proliferate, while less aciduric organisms such as S. sanguis (negative interaction) disappear.
- Aerobic species are replaced by anaerobic species.
Biochemical Reactions in Bacterial Plaque
- Acid production.
- Formation of extracellular and intracellular polysaccharides.
- Demineralization and remineralization phases.
Stephan's Experiment
- Aim: to study pH changes in plaque after glucose intake.
- pH rapidly decrease within 2-5 minutes of glucose ingestion.
- Return to resting pH is slow and depends on caries activity.
Demineralization and Remineralization
- Caries is an alternating process of demineralization and remineralization.
- Remineralization occurs when the consumption of fermentable sugars stops and oral hygiene improves.
Host Factors: Susceptible Tooth
- Position (upper/lower, anterior/posterior, aligned/malaligned teeth).
- Morphology (pits and fissures are more susceptible to caries).
- Structure (enamel hypoplasia, hypocalcification).
- Fluoride (higher fluoride content increases resistance to caries).
Host Factors: Saliva
- Salivary glycoproteins initially protect enamel.
- Saliva helps cleanse the mouth.
- Salivary buffers neutralize acidic pH.
- Lower saliva flow rates increase caries incidence.
Pathology of Dental Caries
- Macroscopic appearance: opaque chalky white areas (white spots).
- Microscopic changes: demineralization and remineralization phases.
- Phases of enamel caries: initiation, bacterial invasion, destruction, and secondary enamel caries.
- Dentin caries: initial non-bacterial lesions, acid attack on dentinal tubules leading to acid-induced demineralization.
Methods to Identify Initial Enamel Caries
- Ordinary light microscope, polarizing light microscope, microradiography, and microhardness testing.
Zones in Longitudinal Ground Sections of Enamel
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- Translucent zone: initial demineralization, appears translucent.
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- Dark zone: further demineralization.
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- Body of the lesion: most demineralization.
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- Surface zone: remineralization zone.
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Description
Test your knowledge about the relationship between carbohydrates and dental caries. This quiz covers the cariogenicity of different types of carbohydrates, the role of bacteria, and the impact of carbohydrate intake on dental health. Explore the factors influencing dental plaque formation and caries susceptibility.