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Questions and Answers
Which route of local anesthetic administration allows for anesthetic effect wherever no layer of intact skin is present?
Which route of local anesthetic administration allows for anesthetic effect wherever no layer of intact skin is present?
- Oral route
- Transdermal route (correct)
- Injection (SC,IM,IV)
- IV administration
What factor is related to the rate of uptake (absorption) in injection administration of local anesthetics?
What factor is related to the rate of uptake (absorption) in injection administration of local anesthetics?
- Lipid solubility
- Vascularity of the injection site (correct)
- Pharmacokinetics
- Vasoactivity of the drug
Which organ will have higher anesthetic blood levels due to being highly perfused?
Which organ will have higher anesthetic blood levels due to being highly perfused?
- Lungs
- Pancreas
- Skeletal muscle (correct)
- Muscle tissue
What process is primarily responsible for the metabolism of amide local anesthetics?
What process is primarily responsible for the metabolism of amide local anesthetics?
What does a higher percentage of protein binding in local anesthetics indicate?
What does a higher percentage of protein binding in local anesthetics indicate?
What is responsible for the hydrolysis of ester local anesthetics in the plasma?
What is responsible for the hydrolysis of ester local anesthetics in the plasma?
Which substance is found in local anesthetic solutions containing epinephrine and acts as an antioxidant and preservative?
Which substance is found in local anesthetic solutions containing epinephrine and acts as an antioxidant and preservative?
Which local anesthetics have allergic potential due to the presence of methylparaben as an antimicrobial?
Which local anesthetics have allergic potential due to the presence of methylparaben as an antimicrobial?
For accurate interpretation during allergy testing for local anesthetics, what must be used?
For accurate interpretation during allergy testing for local anesthetics, what must be used?
Which type of local anesthetics are paraben-free in dental cartridges?
Which type of local anesthetics are paraben-free in dental cartridges?
What is a prime factor involved in the termination of action of local anesthetics?
What is a prime factor involved in the termination of action of local anesthetics?
How do local anesthetics alter the functioning of cells?
How do local anesthetics alter the functioning of cells?
What is combined with lidocaine, bupivacaine, and articaine to enhance the duration and efficacy of the nerve block?
What is combined with lidocaine, bupivacaine, and articaine to enhance the duration and efficacy of the nerve block?
How do most local anesthetics affect blood vessels?
How do most local anesthetics affect blood vessels?
Where must all other drugs, regardless of their route of administration, ultimately enter before they can exert a clinical action?
Where must all other drugs, regardless of their route of administration, ultimately enter before they can exert a clinical action?
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