Dental Anesthesia and Pharmacokinetics Quiz
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Questions and Answers

Which route of local anesthetic administration allows for anesthetic effect wherever no layer of intact skin is present?

  • Oral route
  • Transdermal route (correct)
  • Injection (SC,IM,IV)
  • IV administration
  • What factor is related to the rate of uptake (absorption) in injection administration of local anesthetics?

  • Lipid solubility
  • Vascularity of the injection site (correct)
  • Pharmacokinetics
  • Vasoactivity of the drug
  • Which organ will have higher anesthetic blood levels due to being highly perfused?

  • Lungs
  • Pancreas
  • Skeletal muscle (correct)
  • Muscle tissue
  • What process is primarily responsible for the metabolism of amide local anesthetics?

    <p>Detoxification in the liver</p> Signup and view all the answers

    What does a higher percentage of protein binding in local anesthetics indicate?

    <p>Increased duration of action</p> Signup and view all the answers

    What is responsible for the hydrolysis of ester local anesthetics in the plasma?

    <p>Pseudocholinesterase</p> Signup and view all the answers

    Which substance is found in local anesthetic solutions containing epinephrine and acts as an antioxidant and preservative?

    <p>Bisulfite</p> Signup and view all the answers

    Which local anesthetics have allergic potential due to the presence of methylparaben as an antimicrobial?

    <p>-caine solutions</p> Signup and view all the answers

    For accurate interpretation during allergy testing for local anesthetics, what must be used?

    <p>-caine free solutions</p> Signup and view all the answers

    Which type of local anesthetics are paraben-free in dental cartridges?

    <p>-caine solutions</p> Signup and view all the answers

    What is a prime factor involved in the termination of action of local anesthetics?

    <p>Redistribution from the nerve fiber into the cardiovascular system</p> Signup and view all the answers

    How do local anesthetics alter the functioning of cells?

    <p>By affecting the functioning of some cells</p> Signup and view all the answers

    What is combined with lidocaine, bupivacaine, and articaine to enhance the duration and efficacy of the nerve block?

    <p>Vasoconstrictors</p> Signup and view all the answers

    How do most local anesthetics affect blood vessels?

    <p>They cause vasodilation</p> Signup and view all the answers

    Where must all other drugs, regardless of their route of administration, ultimately enter before they can exert a clinical action?

    <p>Cardiovascular system (CVS)</p> Signup and view all the answers

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