Recent

  • Show all results for ""
quiz image

Dengue Fever Clinical Manifestations and Complications

CherishedEucalyptus avatar
CherishedEucalyptus
·
·
Download

Start Quiz

Study Flashcards

Study Flashcards Play Quiz

Questions and Answers

What percentage of cases exhibit joint pain as a clinical manifestation?

92%

What is the common name of the virus that causes dengue fever?

Flavivirus

What is a complication of dengue fever in pregnant women?

Infection of the developing fetus

What is the duration of recovery from dengue fever?

<p>1 week</p> Signup and view all the answers

What is the vector responsible for transmitting dengue fever?

<p>Aedes aegypti and Aedes albopictus mosquitoes</p> Signup and view all the answers

What is the consequence of removing stagnant water?

<p>Preventing mosquito breeding</p> Signup and view all the answers

What is the consequence of infection with dengue fever?

<p>Immunity to future infections</p> Signup and view all the answers

What is the name of the family of viruses that includes dengue fever?

<p>Flaviviridae</p> Signup and view all the answers

What is a common complication of dengue fever?

<p>All of the above</p> Signup and view all the answers

What is the type of virus that causes dengue fever?

<p>RNA virus</p> Signup and view all the answers

What is the primary site of viral multiplication in a susceptible vertebrate host?

<p>Myeloid and lymphoid cells, and vascular endothelium</p> Signup and view all the answers

What is the role of type 1 interferon (IFN) in CHKV infection?

<p>Production via activation of non-hematopoietic cells</p> Signup and view all the answers

What is the function of the E1 protein in CHKV?

<p>Viral fusion</p> Signup and view all the answers

What is the common route of transmission of CHKV?

<p>Vector-borne transmission through infected mosquitoes</p> Signup and view all the answers

What is the size of the CHKV genome?

<p>11-12 kb</p> Signup and view all the answers

What is the morphology of CHKV?

<p>Spherical, 70 nm in diameter</p> Signup and view all the answers

What is the role of monocyte-derived macrophages in CHKV infection?

<p>Viral tropism</p> Signup and view all the answers

What is the incubation period of CHKV?

<p>2-4 days</p> Signup and view all the answers

What is the outcome of CHKV infection in some cases?

<p>Severe arthritis and joint pain</p> Signup and view all the answers

What is the route of transmission in the laboratory setting?

<p>Aerosol exposure</p> Signup and view all the answers

What is the primary reservoir for the transmission of Dengue virus?

<p>Humans</p> Signup and view all the answers

What is the incubation period of Dengue virus?

<p>3-14 days</p> Signup and view all the answers

What is the purpose of collecting two serum samples for diagnosis?

<p>To identify whether the patient has developed antibodies against the virus</p> Signup and view all the answers

What is the role of infected cells in the pathogenesis of Dengue virus?

<p>They produce signaling proteins</p> Signup and view all the answers

What is the diagnostic method used to detect virus-specific IgM in serum or CSF?

<p>All of the above</p> Signup and view all the answers

What is the size of the Dengue virus genome?

<p>11 kb</p> Signup and view all the answers

What is the result of viral replication in the cells of the mononuclear phagocyte lineage?

<p>Viremia develops within 24 hours</p> Signup and view all the answers

What is the significance of cross-reactivity in making a diagnosis?

<p>It should be considered due to the presence of antibodies to other members of the flavivirus group</p> Signup and view all the answers

What is the purpose of polymerase chain reaction (PCR) assays in laboratory diagnosis?

<p>To detect the presence of viral genome</p> Signup and view all the answers

What is the result of a high viral load in severe cases of Dengue virus infection?

<p>Many vital organs are affected</p> Signup and view all the answers

Which of the following congenital anomalies may occur in a fetus when a pregnant woman is infected with dengue virus?

<p>Multiple congenital anomalies</p> Signup and view all the answers

In which trimester of pregnancy does dengue virus infection pose the greatest risk to the fetus?

<p>Later in pregnancy</p> Signup and view all the answers

What is a possible outcome of dengue fever infection in people above 65 years old?

<p>Increased severity of symptoms</p> Signup and view all the answers

What is the benefit of removing stagnant water from the environment?

<p>Prevents mosquito breeding</p> Signup and view all the answers

What is the duration of immunity to dengue fever virus after infection?

<p>Lifetime immunity</p> Signup and view all the answers

What is the family of viruses that includes dengue fever?

<p>Flaviviridae</p> Signup and view all the answers

What is a characteristic clinical manifestation of dengue fever?

<p>Joint pain</p> Signup and view all the answers

What is the consequence of dengue fever infection in people with underlying conditions?

<p>Increased risk of complications</p> Signup and view all the answers

What is the incubation period of dengue fever?

<p>Recovery: 1 week, but may persist</p> Signup and view all the answers

Which of the following is NOT a complication of dengue fever?

<p>Meningitis</p> Signup and view all the answers

What is the primary site of viral replication in the host after the initial infection?

<p>Skin</p> Signup and view all the answers

What is the role of E2 protein in CHKV?

<p>Mediates cell attachment</p> Signup and view all the answers

What is the outcome of CHKV infection in some cases?

<p>Severe joint pain</p> Signup and view all the answers

What is the mechanism by which CHKV triggers an innate immune response?

<p>Activation of type 1 interferon (IFN)</p> Signup and view all the answers

What is the primary mode of transmission of CHKV in the urban cycle?

<p>Vector-borne transmission</p> Signup and view all the answers

What is the significance of the blood-brain barrier in CHKV infection?

<p>Prevents viral replication in the CNS</p> Signup and view all the answers

What is the characteristic of the nucleocapsid of CHKV?

<p>Spherical structure with 42 capsomeres</p> Signup and view all the answers

What is the primary role of fibroblasts in CHKV infection?

<p>Viral replication</p> Signup and view all the answers

What is the significance of the sylvatic cycle in CHKV transmission?

<p>Transmission from animal to human</p> Signup and view all the answers

What is the type of RNA present in the CHKV genome?

<p>Positive-sense RNA</p> Signup and view all the answers

What is the primary mechanism by which Dengue virus is transmitted?

<p>Through a bite of an infected female Aedes mosquito</p> Signup and view all the answers

What is the role of infected macrophages in Dengue virus infection?

<p>To produce signaling proteins: Interferons, Cytokines, Chemokines, TNF</p> Signup and view all the answers

What is the significance of collecting two serum samples for diagnosis?

<p>To identify whether the patient has antibodies against the causative agent</p> Signup and view all the answers

What is the characteristic of the Dengue virus genome?

<p>Positive-sense, single stranded RNA</p> Signup and view all the answers

What is the primary reservoir of Dengue virus transmission?

<p>Humans</p> Signup and view all the answers

What is the method used to detect virus-specific IgM in serum or CSF?

<p>IgM-capture ELISA</p> Signup and view all the answers

What is the consequence of a high viral load in severe cases of Dengue virus infection?

<p>A very high viral load affecting many vital organs</p> Signup and view all the answers

What is the role of type 1 interferon (IFN) in Dengue virus infection?

<p>To inhibit viral replication</p> Signup and view all the answers

What is the morphology of Dengue virus?

<p>Spherical, 40-60 nm in diameter</p> Signup and view all the answers

What is the significance of cross-reactivity in making a diagnosis?

<p>It indicates the presence of antibodies against other members of the flavivirus group</p> Signup and view all the answers

The incubation period of dengue fever is typically less than 1 week.

<p>False</p> Signup and view all the answers

Dengue fever can only be transmitted through the bite of an infected Aedes albopictus mosquito.

<p>False</p> Signup and view all the answers

Infection with dengue fever provides lifelong immunity against subsequent infections.

<p>True</p> Signup and view all the answers

The primary site of viral replication in the host after the initial infection is the liver.

<p>False</p> Signup and view all the answers

Dengue fever can cause congenital anomalies in the fetus if the mother is infected during the first trimester of pregnancy.

<p>True</p> Signup and view all the answers

Removing stagnant water from the environment can prevent the transmission of dengue fever.

<p>True</p> Signup and view all the answers

Louis encephalitis is a congenital disease that can be caused by intrauterine infection during the first trimester.

<p>True</p> Signup and view all the answers

Dengue virus has a negative-sense, single-stranded RNA genome.

<p>False</p> Signup and view all the answers

Aedes albopictus is a minor vector of Dengue virus transmission.

<p>False</p> Signup and view all the answers

Viral replication in the cells of the mononuclear phagocyte lineage leads to the production of interferons and cytokines.

<p>True</p> Signup and view all the answers

The diagnosis of Dengue virus infection is confirmed by detecting virus-specific IgG antibodies in serum or CSF.

<p>False</p> Signup and view all the answers

Dengue virus infection is treatable with a vaccine.

<p>False</p> Signup and view all the answers

The incubation period of CHKV is 1-2 weeks.

<p>False</p> Signup and view all the answers

CHKV is classified in the virus family Flaviviridae.

<p>False</p> Signup and view all the answers

The primary site of viral multiplication in a susceptible vertebrate host is the liver.

<p>False</p> Signup and view all the answers

Type 1 interferon (IFN) is produced via activation of hematopoietic cells.

<p>False</p> Signup and view all the answers

The urban cycle of CHKV transmission involves transmission from an animal to a mosquito to a human.

<p>False</p> Signup and view all the answers

The genome of CHKV is double-stranded DNA.

<p>False</p> Signup and view all the answers

CHKV is primarily transmitted through the bite of an infected tick.

<p>False</p> Signup and view all the answers

CHKV infection can be diagnosed through the detection of virus-specific IgG in serum or CSF.

<p>False</p> Signup and view all the answers

More Quizzes Like This

Dengue Fever Quiz
10 questions

Dengue Fever Quiz

JovialPrairieDog7842 avatar
JovialPrairieDog7842
Dengue Fever Quiz
5 questions

Dengue Fever Quiz for Students: Test Your Knowledge

FantasticSplendor avatar
FantasticSplendor
Dengue Fever Symptoms and Recovery
13 questions

Dengue Fever Symptoms and Recovery

InfluentialRationality avatar
InfluentialRationality
Prevention of Dengue Fever
18 questions

Prevention of Dengue Fever

RealizableLutetium avatar
RealizableLutetium
Use Quizgecko on...
Browser
Open
Browser
Browser