Pathway 13-2-6 Cells of the Pulp Dendritic Cell
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Questions and Answers

What is the primary role of dendritic cells within the immune system?

  • To directly kill infected cells
  • To transport antigens to lymph nodes
  • To produce antibodies against pathogens
  • To assist in the activation of T cells (correct)
  • Where are dendritic cells predominantly found in the body?

  • In the bone marrow
  • In the bloodstream
  • In lymphoid tissues and connective tissues (correct)
  • In muscle tissues
  • Which of the following is characteristic of dendritic cells?

  • Ability to produce cytokines in large quantities
  • Dendritic cytoplasmic processes (correct)
  • Presence of class I MHC complexes on their surface
  • They do not migrate in response to antigens
  • What occurs when a peptide fragment of an antigen binds to a T-cell receptor?

    <p>T-cell activation occurs</p> Signup and view all the answers

    In response to antigenic challenges, where do dendritic cells migrate within the pulp?

    <p>Centrally within the pulp</p> Signup and view all the answers

    What defines dendritic cells as antigen-presenting cells?

    <p>The presence of class II MHC molecules and engulfment of protein antigens</p> Signup and view all the answers

    Which cells are dendritic cells similar to in function and morphology? AKA what is its other name?

    <p>Langerhans cells</p> Signup and view all the answers

    Study Notes

    Dendritic Cells

    • Immune system accessory cells
    • Found in lymphoid tissues, connective tissues, and epidermis
    • Also called Langerhans cells in the epidermis and mucous membranes
    • Antigen-presenting cells
    • Characterized by dendritic cytoplasmic processes and class II MHC complexes on their cell surface
    • Primarily found in the periphery of coronal pulp, but migrate centrally after antigenic challenge
    • Play a central role in the induction of T-cell–dependent immunity
    • Engulf protein antigens and present peptide fragments of the antigens and MHC class II molecules
    • This assembly is recognized by T cells, binding to their T-cell receptors and activating them.
    • Can interact directly with lymphocytes.

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