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Questions and Answers
What is the primary role of dendritic cells within the immune system?
Where are dendritic cells predominantly found in the body?
Which of the following is characteristic of dendritic cells?
What occurs when a peptide fragment of an antigen binds to a T-cell receptor?
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In response to antigenic challenges, where do dendritic cells migrate within the pulp?
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What defines dendritic cells as antigen-presenting cells?
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Which cells are dendritic cells similar to in function and morphology? AKA what is its other name?
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Study Notes
Dendritic Cells
- Immune system accessory cells
- Found in lymphoid tissues, connective tissues, and epidermis
- Also called Langerhans cells in the epidermis and mucous membranes
- Antigen-presenting cells
- Characterized by dendritic cytoplasmic processes and class II MHC complexes on their cell surface
- Primarily found in the periphery of coronal pulp, but migrate centrally after antigenic challenge
- Play a central role in the induction of T-cell–dependent immunity
- Engulf protein antigens and present peptide fragments of the antigens and MHC class II molecules
- This assembly is recognized by T cells, binding to their T-cell receptors and activating them.
- Can interact directly with lymphocytes.
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