Deafferentation and Pain

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Questions and Answers

What is the common cause of deafferentation leading to pain?

  • Chronic inflammation
  • Infection of the tooth
  • Trauma or surgery (correct)
  • Neurodegenerative disease

What is the effect of local anesthetic block on pain in cases of CNS hyperactivity?

  • It reduces the pain but does not eliminate it
  • It increases the pain
  • It arrests the pain
  • It has no effect on the pain (correct)

What is the mechanism underlying peripheral hyperactivity leading to pain?

  • Inflammation of the nerve tissue
  • Neuronal hyperactivity at the site of nerve damage (correct)
  • Demyelination of the nerve fibers
  • Changes in the CNS lead to changes in the peripheral nerve

What is the role of the trigeminal nucleus in the development of pain due to deafferentation?

<p>It is the site of synaptic changes leading to CNS hyperactivity (D)</p> Signup and view all the answers

What is the characteristic of pain experienced in deafferentation due to CNS hyperactivity?

<p>It can occur despite minimal or no peripheral input (B)</p> Signup and view all the answers

What is the similarity between phantom limb pain and oral deafferentation pain?

<p>They both involve amputation of tissue (D)</p> Signup and view all the answers

What is a characteristic of deafferentation pains in relation to peripheral surgical procedures?

<p>They are frequently intensified by peripheral surgical procedures (C)</p> Signup and view all the answers

What percentage of persons will have had a bout of shingles by age 85 years?

<p>25% (C)</p> Signup and view all the answers

What is the primary key to recognizing conditions like deafferentation pains and avoiding unnecessary dental treatment?

<p>Obtaining an excellent description of the chief complaint (D)</p> Signup and view all the answers

What is the approximate percentage of patients who will develop postherpetic neuralgia (PHN) after an episode of shingles?

<p>60% to 70% (C)</p> Signup and view all the answers

What is the role of the sympathetic nervous system in neuropathic pain processes?

<p>It augments the complexity of pain processes (D)</p> Signup and view all the answers

What is the typical age range for the onset of shingles?

<p>Any age, but more common in older patients (D)</p> Signup and view all the answers

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