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Deafferentation and Pain

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Questions and Answers

What is the common cause of deafferentation leading to pain?

Chronic inflammation

Infection of the tooth

Trauma or surgery (correct)

Neurodegenerative disease

What is the effect of local anesthetic block on pain in cases of CNS hyperactivity?

It reduces the pain but does not eliminate it

It increases the pain

It arrests the pain

It has no effect on the pain (correct)

What is the mechanism underlying peripheral hyperactivity leading to pain?

Inflammation of the nerve tissue

Neuronal hyperactivity at the site of nerve damage (correct)

Demyelination of the nerve fibers

Changes in the CNS lead to changes in the peripheral nerve

What is the role of the trigeminal nucleus in the development of pain due to deafferentation?

It is the site of synaptic changes leading to CNS hyperactivity Signup and view all the answers

What is the characteristic of pain experienced in deafferentation due to CNS hyperactivity?

It can occur despite minimal or no peripheral input Signup and view all the answers

What is the similarity between phantom limb pain and oral deafferentation pain?

They both involve amputation of tissue Signup and view all the answers

What is a characteristic of deafferentation pains in relation to peripheral surgical procedures?

They are frequently intensified by peripheral surgical procedures Signup and view all the answers

What percentage of persons will have had a bout of shingles by age 85 years?

25% Signup and view all the answers

What is the primary key to recognizing conditions like deafferentation pains and avoiding unnecessary dental treatment?

Obtaining an excellent description of the chief complaint Signup and view all the answers

What is the approximate percentage of patients who will develop postherpetic neuralgia (PHN) after an episode of shingles?

60% to 70% Signup and view all the answers

What is the role of the sympathetic nervous system in neuropathic pain processes?

It augments the complexity of pain processes Signup and view all the answers

What is the typical age range for the onset of shingles?

Any age, but more common in older patients Signup and view all the answers