Deafferentation and Pain

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12 Questions

What is the common cause of deafferentation leading to pain?

Trauma or surgery

What is the effect of local anesthetic block on pain in cases of CNS hyperactivity?

It has no effect on the pain

What is the mechanism underlying peripheral hyperactivity leading to pain?

Neuronal hyperactivity at the site of nerve damage

What is the role of the trigeminal nucleus in the development of pain due to deafferentation?

It is the site of synaptic changes leading to CNS hyperactivity

What is the characteristic of pain experienced in deafferentation due to CNS hyperactivity?

It can occur despite minimal or no peripheral input

What is the similarity between phantom limb pain and oral deafferentation pain?

They both involve amputation of tissue

What is a characteristic of deafferentation pains in relation to peripheral surgical procedures?

They are frequently intensified by peripheral surgical procedures

What percentage of persons will have had a bout of shingles by age 85 years?

25%

What is the primary key to recognizing conditions like deafferentation pains and avoiding unnecessary dental treatment?

Obtaining an excellent description of the chief complaint

What is the approximate percentage of patients who will develop postherpetic neuralgia (PHN) after an episode of shingles?

60% to 70%

What is the role of the sympathetic nervous system in neuropathic pain processes?

It augments the complexity of pain processes

What is the typical age range for the onset of shingles?

Any age, but more common in older patients

Learn about the causes and examples of deafferentation, a condition that leads to pain due to damage to the afferent pain transmission system. Discover how trauma, surgery, extraction, and endodontic treatment can cause deafferentation, and how it relates to phantom limb pain.

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