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Questions and Answers
Dantrolene's primary mechanism of action involves?
Dantrolene's primary mechanism of action involves?
- Increasing the sensitivity of muscle fibers to calcium.
- Enhancing the uptake of calcium into muscle tubules.
- Promoting the storage of calcium within muscle cells.
- Blocking the release of calcium from the muscle tubules. (correct)
Which of the following is a primary indication for Dantrolene use?
Which of the following is a primary indication for Dantrolene use?
- Relief of muscle spasticity directly affecting peripheral muscle contraction. (correct)
- Treatment of muscle weakness due to nerve damage.
- Prevention of muscle atrophy in immobilized patients.
- Enhancement of muscle strength in elderly patients.
In which scenario would Dantrolene be contraindicated?
In which scenario would Dantrolene be contraindicated?
- Muscle stiffness following intense exercise.
- Muscle spasms in the lower back.
- Muscle spasticity impairing locomotion.
- Muscle spasticity contributing to improved posture and function. (correct)
Which of the following represents a potential adverse effect associated with Dantrolene?
Which of the following represents a potential adverse effect associated with Dantrolene?
What routes of administration are recommended for Dantrolene?
What routes of administration are recommended for Dantrolene?
A patient taking Dantrolene reports experiencing heart palpitations. Which of the following actions is MOST appropriate?
A patient taking Dantrolene reports experiencing heart palpitations. Which of the following actions is MOST appropriate?
Dantrolene is being considered for a patient who also takes anticholinergics. Why is it important to evaluate this combination?
Dantrolene is being considered for a patient who also takes anticholinergics. Why is it important to evaluate this combination?
A patient prescribed Dantrolene reports new onset urinary retention. What is the MOST likely cause?
A patient prescribed Dantrolene reports new onset urinary retention. What is the MOST likely cause?
Which of the following effects of Dantrolene is most likely to cause a safety concern for an elderly patient?
Which of the following effects of Dantrolene is most likely to cause a safety concern for an elderly patient?
A patient with a history of psychosis is prescribed an antipsychotic medication. How might this interact with Dantrolene?
A patient with a history of psychosis is prescribed an antipsychotic medication. How might this interact with Dantrolene?
Flashcards
Dantrolene
Dantrolene
Interferes with the release of calcium from muscle tubules.
Indications of Dantrolene
Indications of Dantrolene
Treatment of spasticity directly affecting peripheral muscles.
Dantrolene Routes
Dantrolene Routes
Oral or IV
Contraindication of Dantrolene
Contraindication of Dantrolene
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Adverse Effects of Dantrolene
Adverse Effects of Dantrolene
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Drug-Drug Interactions
Drug-Drug Interactions
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Study Notes
- Dantrolene is a direct-acting muscle relaxant
Mechanism
- Interferes with the release of calcium from the muscle tubules
Indications
- Used for the treatment of spasticity directly affecting peripheral muscle contraction
Route
- Can be administered orally
- or intravenously (IV)
Contraindication
- Contraindicated in spasticity in a muscle that contributes to locomotion, upright position, or increased function
Adverse Effects
- Can cause CNS depression
- May result in GI disturbances
- Palpitations can occur
- Hypotension is a potential side effect
- Can lead to urinary retention
Drug-Drug Interactions
- Interacts with anticholinergics
- Also interacts with antipsychotics
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