NUCLEIC ACID
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Questions and Answers

Which biomolecule is responsible for the storage and expression of genetic information?

  • Lipids
  • Proteins
  • Nucleic acids (correct)
  • Carbohydrates

What are the two types of nucleic acids mentioned in the text?

  • Thymine and Cytosine
  • RNA and DNA (correct)
  • Adenine and Guanine
  • Ribose and Deoxyribose

What is the basic structure of a nucleotide according to the text?

  • Hydrogen, carbon, and oxygen
  • Adenine, thymine, and cytosine
  • Ribose, deoxyribose, and guanine
  • Phosphate, sugar, and nitrogen base (correct)

Which component makes up the backbone of a polynucleotide chain?

<p>Phosphate (D)</p> Signup and view all the answers

How many hydrogen bonds are there between adenine and thymine in DNA according to the text?

<p>2 hydrogen bonds (C)</p> Signup and view all the answers

What is the rule mentioned in the text regarding the base pairing in DNA?

<p>A-T = C-G (D)</p> Signup and view all the answers

Which type of nucleic acid is right-handed?

<p>B DNA (A)</p> Signup and view all the answers

Given a DNA with 11% C, what is the A %?

<p>39% (A)</p> Signup and view all the answers

What are the nitrogenous bases found in RNA according to the text?

<p>Adenine, Uracil, Guanine, Cytosine (C)</p> Signup and view all the answers

Which component forms phosphodiester bonds in a nucleic acid chain according to the text?

<p>Phosphate (A)</p> Signup and view all the answers

What type of helix is formed by DNA according to the text?

<p>Double helix (C)</p> Signup and view all the answers

During DNA replication, which enzyme is responsible for unwinding the DNA helix?

<p>Topoisomerase (D)</p> Signup and view all the answers

In DNA replication, what is the role of primase?

<p>Initiating the formation of the RNA primer (C)</p> Signup and view all the answers

Which enzyme is involved in the termination of transcription in prokaryotes by recognizing specific DNA sequences?

<p>Rho-dependent termination factor (C)</p> Signup and view all the answers

What is the role of the Shine-Dalgarno sequence in prokaryotic translation?

<p>Promoting ribosomal binding to the mRNA (D)</p> Signup and view all the answers

What is the function of transfer RNA (tRNA) during translation?

<p>Bringing amino acids to the ribosome (C)</p> Signup and view all the answers

What is meant by the term 'degenerate' in relation to the genetic code?

<p>Some amino acids have multiple codons that code for them (A)</p> Signup and view all the answers

What type of mutation results in a change from a purine base to another purine base?

<p>Transition (B)</p> Signup and view all the answers

Which post-translational modification involves the folding of a newly synthesized protein into its correct three-dimensional structure?

<p>Folding (C)</p> Signup and view all the answers

What is the primary function of chaperone proteins in post-translational modifications?

<p>Assisting in protein folding (C)</p> Signup and view all the answers

Which enzyme is responsible for proofreading the newly synthesized DNA during replication and making corrections?

<p>DNA polymerase (D)</p> Signup and view all the answers

What is the role of termination factor Rho in prokaryotic transcription?

<p>Causing dissociation of RNA polymerase from DNA template at specific sequences (B)</p> Signup and view all the answers

During translation, which molecule brings amino acids to the ribosome based on the mRNA codon?

<p>Transfer RNA (tRNA) (B)</p> Signup and view all the answers

Flashcards

Nucleic acids: Genetic information

Nucleic acids are biomolecules responsible for storing and expressing genetic information.

Types of nucleic acids

RNA and DNA are the two primary types of nucleic acids.

Nucleotide structure

A nucleotide comprises a phosphate group, a sugar molecule, and a nitrogenous base.

Phosphate backbone

The phosphate group forms the backbone of a polynucleotide chain.

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Adenine-Thymine bond

Adenine and thymine form two hydrogen bonds in DNA.

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Base pairing rule

The base pairing rule in DNA is A-T and C-G.

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B DNA: Right-handed

B DNA, a form of DNA, has a right-handed helix.

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Adenine percentage

If a DNA molecule contains 11% cytosine, then adenine will be present in 39%.

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RNA bases

RNA contains the nitrogenous bases adenine, uracil, guanine, and cytosine.

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Phosphodiester bonds

The phosphate group forms phosphodiester bonds in a nucleic acid chain.

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DNA structure

DNA adopts a double helix structure.

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Topoisomerase function

Topoisomerase unwinds the DNA helix during replication.

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Primase role

Primase initiates the formation of the RNA primer in DNA replication.

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Rho-dependent termination

Rho-dependent termination factor recognizes specific DNA sequences in prokaryotes, ending transcription.

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Shine-Dalgarno sequence

The Shine-Dalgarno sequence promotes ribosomal binding to mRNA in prokaryotic translation.

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tRNA function

Transfer RNA (tRNA) brings amino acids to the ribosome during translation.

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Genetic code: Degenerate

The genetic code is degenerate, meaning some amino acids have multiple codons.

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Transition mutation

A transition mutation changes a purine base to another purine base (A to G or G to A).

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Protein folding

Folding refers to the post-translational modification where a newly synthesized protein gains its correct three-dimensional structure.

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Chaperone proteins

Chaperone proteins assist in protein folding during post-translational modifications.

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DNA polymerase: Proofreading

DNA polymerase proofreads the newly synthesized DNA during replication and makes corrections.

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Rho factor termination

Termination factor Rho causes RNA polymerase to dissociate from the DNA template at specific sequences in prokaryotic transcription.

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tRNA: Codon recognition

Transfer RNA (tRNA) brings amino acids to the ribosome based on the mRNA codon during translation.

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