23 Questions
What is the function of centrosomes during cell division?
Nucleating microtubules to help form the mitotic spindle
Which organelle is the centrosome a form of?
Centrioles
What is the primary function of microtubules in neurons?
Transporting organelles and materials within the cell
Which disease has been associated with reduced microtubule stability?
Alzheimer's disease
What is the size comparison between microfilaments and microtubules?
Microfilaments are smaller than microtubules
What is a characteristic feature of microfilaments in terms of assembly and disassembly?
Exhibit dynamic assembly and disassembly known as treadmilling
Which biological process involves microfilaments primarily?
Cell transport
Which function is NOT attributed to the cytoskeleton in the text?
Generating energy for cellular processes
What is a characteristic of microtubules based on the text?
They help prevent cell collapse as support beams
How are microtubules described in terms of dynamics?
They switch between shrinking and growing states
What is the composition of microtubules according to the text?
Dimers of α- and β-Tubulin forming polymer sheets
What initiates the formation of Microtubule Organizing Centres (MTOCs) in cells?
Centrioles
Which statement accurately describes the structure of microtubules?
Hollow tubes made up of polymerized α- and β-Tubulin dimers
What feature enables microtubules to withstand some compression according to the text?
The lumen running through them
Which proteins form dimers to create microtubules?
'α'-Tubulin and 'β'-Tubulin
What is the function of Microtubule Organizing Centres (MTOCs) in cells?
Mitosis regulation
What is a key aspect of the dynamics of microtubules?
Rapid addition or removal of dimers at their dynamic ends
How do microtubules bypass the need for a 'seed' during their formation?
Utilizing γ-tubulin and accessory protein
Which type of microtubules is responsible for forming a contractile ring around the 'waist' of the cell during cell division?
Interpolar microtubules
Which disease has shown a decrease in microtubule stability as observed in the text?
Motor neurone disease
What type of filaments are keratin intermediate fibers that resist shear stress in epithelial cells of the airway?
Intermediate filaments
In response to signals downstream of cell surface receptors, which cytoskeletal network protrudes to facilitate endocytosis?
Actin filaments
Which group of intermediate filaments is the largest based on sequence similarity?
Type I and Type II keratins
Learn about the functions and composition of the cytoskeleton, a support framework within cells that enables movement, organization, and connection to the external environment. Explore the dynamic and adaptive nature of the cytoskeleton and its similarities to LEGO structures.
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