Podcast
Questions and Answers
Which of the following characteristics is unique to microfilaments compared to other components of the cytoskeleton?
Which of the following characteristics is unique to microfilaments compared to other components of the cytoskeleton?
- Utilization of ATP hydrolysis for movement
- Involvement in cell crawling and migration (correct)
- Association with motor proteins like dynein and kinesin
- Ability to facilitate intracellular transport of vesicles
What would be the most likely outcome if a cell's ability to polymerise G-actin into F-actin was completely inhibited?
What would be the most likely outcome if a cell's ability to polymerise G-actin into F-actin was completely inhibited?
- Improved structural support, preventing cell shape changes.
- Disruption of muscle contraction and cell migration. (correct)
- Increased efficiency in vesicle transport within the cell.
- Enhanced movement of organelles towards the positive pole of microtubules.
In the context of intracellular transport, how do dynein and kinesin differ in their functions?
In the context of intracellular transport, how do dynein and kinesin differ in their functions?
- Dynein facilitates retrograde transport, while kinesin is responsible for anterograde transport. (correct)
- Dynein is involved in muscle contraction, while kinesin facilitates cell crawling.
- Dynein moves towards the positive pole while kinesin moves towards the negative pole.
- Dynein uses microfilaments for movement, while kinesin uses microtubules.
If a drug were developed to selectively inhibit the activity of myosin, which cellular process would be most directly affected?
If a drug were developed to selectively inhibit the activity of myosin, which cellular process would be most directly affected?
Considering the role of the cytoskeleton in cell movement, which of the following scenarios could potentially have negative consequences?
Considering the role of the cytoskeleton in cell movement, which of the following scenarios could potentially have negative consequences?
How does the polarity of actin filaments (microfilaments) contribute to cell movement and function?
How does the polarity of actin filaments (microfilaments) contribute to cell movement and function?
How does ATP hydrolysis contribute to the function of the actin-myosin system in muscle cells?
How does ATP hydrolysis contribute to the function of the actin-myosin system in muscle cells?
What role do microtubules play in maintaining the structure and function of cilia and flagella?
What role do microtubules play in maintaining the structure and function of cilia and flagella?
A researcher is studying a cell line with a mutation that disrupts the function of kinesin. What cellular process would be most directly affected by this mutation?
A researcher is studying a cell line with a mutation that disrupts the function of kinesin. What cellular process would be most directly affected by this mutation?
Which of the following aspects differentiates the movement facilitated by actin-myosin interactions from movement due to microtubule-associated motor proteins?
Which of the following aspects differentiates the movement facilitated by actin-myosin interactions from movement due to microtubule-associated motor proteins?
Flashcards
Cytoskeleton
Cytoskeleton
Active, dynamic system crucial for cell movement and functions.
Microfilaments
Microfilaments
Made of G-actin monomers that polymerize into F-actin with a barbed (+) and pointed (-) end.
Myosin
Myosin
Interacts with actin, using ATP to enable cellular movements.
Dynein
Dynein
Signup and view all the flashcards
Kinesin
Kinesin
Signup and view all the flashcards
Muscle Contraction
Muscle Contraction
Signup and view all the flashcards
Study Notes
Cytoskeleton: The Cell's Dynamic Infrastructure
- The cytoskeleton serves as an active and dynamic system vital for cellular functions.
Microfilaments (Actin-Based System)
- Composed of G-actin monomers that polymerize into F-actin.
- Exhibits polarity, featuring a "barbed" (+) end and a "pointed" (-) end.
- Facilitates cell crawling, muscle contraction, and immune cell migration.
Motor Protein Interactions
- Myosin interacts with actin to enable movement.
- Movement is powered by ATP hydrolysis.
- Critical for muscle cells, immune cell migration, and wound healing
- Can cause cancer metastasis and pathological cell migrations.
Intracellular Transport
- Relies on motor proteins dynein and kinesin to move cargo along microtubules
Microtubule-Based Transport
- Dynein moves towards the negative pole (retrograde).
- Kinesin moves towards the positive pole (anterograde).
- Facilitates vesicle transport, organelle positioning, and cilia and flagella movement.
Skeletal Muscle Function
- Depends on actin-myosin interactions.
- Movement powered by ATP along microfilaments.
- Enables muscle fiber contraction and relaxation.
Studying That Suits You
Use AI to generate personalized quizzes and flashcards to suit your learning preferences.
