Cytoplasmic Acetyl-CoA Origin
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Questions and Answers

From which two sources is the cytoplasmic acetyl-CoA primarily generated in the mitochondria?

Pyruvate dehydrogenase (PDH) reaction and fatty acid oxidation

What must be the condition for the acetyl-CoA units to be utilized for fatty acid synthesis in the cytoplasm?

Presence in the cytoplasm

When does the shift from fatty acid oxidation and glycolytic oxidation, as well as amino acid metabolism, occur?

When the need for energy diminishes

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