immunotherapy
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immunotherapy

Identify two commonly used cytokines in cancer treatment. Cytokines are signaling molecules that help regulate the immune response. In this quiz, you will learn about two essential cytokines used in cancer therapy.

Created by
@MindBlowingCognition

Questions and Answers

name 2 of the most common cytokines used in cancer therapy

interleukin 2 (IL-2)and interferon alpha

what is the function of interleukin-2

IL-2 is a cytokine that plays a critical role in the activation and proliferation of T cells which recognise and destroy cancer cells

what is the function of Interferon- alpha

IFN-a is used to stimulate the immune system antitumour response by enhancing the activity of immune cells like natural killer cells and cytotoxic T lymphocytes.

what is the function of interferons?

<p>activating the immune system and exerting anti-tumour effects</p> Signup and view all the answers

what is the main function of immune system modulators

<p>to activate the immune system and promote anti-tumour activity</p> Signup and view all the answers

describe the action of monoclonal antibodies in cancer therapy

<p>binding to a cell surface molecule (eg.CD20 on b ell tumours) on tumour cells, inducing apoptosis</p> Signup and view all the answers

how does adoptive t-cell therapy work?

<p>taking T-cells and making them more able to kill tumours by stimulating them in vitro then administering them back into the patient</p> Signup and view all the answers

how does CART therapy work?

<p>take blood from a patient, isolate the T cells, introduce a chimeric antigen receptor and grow these cells then administer them back into the patient</p> Signup and view all the answers

what two ways can T cells be switched off?

<p>in the tumour environment (PDL-1 and PD1) and in the environment where T cells are being stimulated by antigen-presenting cells</p> Signup and view all the answers

how do tumours switch off T cells? (2 ways)

<p>PDL-1 binds to PD-1 which switches off T cells. in lymph nodes CTLA-4 can bind proteins that switches off T cells.</p> Signup and view all the answers

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