Cytokine Network Interaction Quiz
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Questions and Answers

What determines the susceptibility of a target cell to a particular cytokine?

  • Alteration of gene expression
  • Specific membrane receptors (correct)
  • Secretion by immune cells
  • Low-molecular-weight proteins
  • Which type of action do cytokines exert when binding to receptors on target cells in close proximity to the producer cell?

  • Endocrine action
  • Paracrine action (correct)
  • Pleiotropic action
  • Synergistic action
  • In what way do cytokines regulate the intensity and duration of the immune response?

  • By reducing the secretion of antibodies
  • By stimulating activation and proliferation (correct)
  • By inhibiting gene expression
  • By altering stem cell function
  • What is the mode of action called when a cytokine binds to receptors on target cells in distant parts of the body?

    <p>Endocrine action</p> Signup and view all the answers

    Which cell type is NOT mentioned as a source of cytokines in the provided text?

    <p>Erythrocytes</p> Signup and view all the answers

    What pathway do cytokines trigger upon binding to specific receptors on target cells?

    <p>Signal-transduction pathway</p> Signup and view all the answers

    Which of the following is a therapeutic use of cytokines?

    <p>Treatment of arthritis</p> Signup and view all the answers

    In what condition is GM-CSF helpful according to the text?

    <p>Neutropenia</p> Signup and view all the answers

    Which of the following diseases involves the modification of the immune response using cytokines during organ transplantation?

    <p>Organ rejection</p> Signup and view all the answers

    In which condition might cytokines be used to increase the number of neutrophils to overcome infectious hazards?

    <p>Neutropenia</p> Signup and view all the answers

    What is a common therapeutic use of cytokines according to the text?

    <p>Cancer therapy</p> Signup and view all the answers

    Which family of cytokine receptors includes ligands such as IL-2, IL-4, and IL-6?

    <p>Class I cytokine receptor family</p> Signup and view all the answers

    Which cytokine receptor family is also known as the interferon receptor family?

    <p>Class II cytokine receptor family</p> Signup and view all the answers

    Which family of cytokine receptors has ligands that include TNF-α, TNF-β, and CD40?

    <p>TNF receptor family</p> Signup and view all the answers

    Which type of cytokine receptor belongs to the Immunoglobulin superfamily?

    <p>Class I cytokine receptor family</p> Signup and view all the answers

    The Chemokine receptor family has ligands such as:

    <p>IL-8, MCAF</p> Signup and view all the answers

    'Granulocyte-monocyte colony stimulating factor' is associated with which cytokine receptor?

    <p>Class I cytokine receptor family</p> Signup and view all the answers

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