Cystic Fibrosis Symptoms and Diagnosis

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Why is newborn screening for cystic fibrosis important?

To identify digestive issues

To detect lung infections

To diagnose respiratory symptoms

To allow for early detection and intervention (correct)

What is the primary purpose of genetic testing for cystic fibrosis?

To diagnose respiratory symptoms

To identify specific CFTR gene mutations (correct)

To detect digestive issues

To identify lung infections

Why do dentists need to be cautious when treating patients with cystic fibrosis?

Because of potential medication interactions

Because of compromised immune function

Because of respiratory complications

All of the above (correct)

What is the difference in life expectancy between male and female patients with cystic fibrosis?

Female patients have a shorter life expectancy than male patients Signup and view all the answers

What can preventive dental care help prevent in individuals with cystic fibrosis?

Cavities and gum disease Signup and view all the answers

Why may CF patients have difficulty tolerating certain dental equipment or procedures?

Due to respiratory condition or sensitivity to stimuli Signup and view all the answers

What is the primary reason for the high incidence of tooth discoloration in patients with cystic fibrosis?

The defects in the permanent teeth Signup and view all the answers

What is a common respiratory symptom in patients with cystic fibrosis?

Shortness of breath Signup and view all the answers

Why do patients with cystic fibrosis have a lower caries rate?

The effects of long-term antibiotic therapy on the oral microbiota Signup and view all the answers

What is a common dental issue in patients with cystic fibrosis due to chronic nasal and sinus obstruction?

Mouth breathing and anterior open bite Signup and view all the answers

What type of mutation is responsible for approximately 70% of affected alleles in Cystic Fibrosis?

Class 2 defect Signup and view all the answers

What is the primary function of the CFTR gene in the human body?

To provide instructions for the production of the CFTR protein Signup and view all the answers

What is a common symptom of Cystic Fibrosis that affects the digestive system?

Thick and sticky mucus in the digestive tract Signup and view all the answers

What is the name of the gene responsible for Cystic Fibrosis?

CFTR Signup and view all the answers

What is the location of the CFTR gene?

On the seventh pair of chromosomes Signup and view all the answers

What is the primary function of the CFTR protein in the body?

To maintain the balance of salt and water on many surfaces Signup and view all the answers

What happens to the mucus covering the cells when the CFTR protein is not working correctly?

It becomes thick and sticky Signup and view all the answers

What is the result of the dysfunctional CFTR protein in the respiratory epithelium?

A decrease in the water volume and compression of the cilia by mucus Signup and view all the answers

What is the effect of the impaired CFTR protein on the airway surface layer?

It becomes dehydrated and retracted Signup and view all the answers

What is the geographic distribution of cystic fibrosis?

It is most prevalent in Europe, North America, and Australia Signup and view all the answers