Cystic Fibrosis: Causes, Symptoms, and Treatment
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Questions and Answers

What is the primary defect in Cystic Fibrosis?

  • Abnormal transport of sodium ions
  • Inefficient transport of oxygen in the lungs
  • Defect in chloride channel protein (correct)
  • Impaired pancreatic enzyme secretion

Which type of lung cancer has the lowest association with smoking?

  • Squamous cell carcinoma
  • Adenocarcinoma (correct)
  • Large cell carcinoma
  • Bronchoalveolar cell carcinoma

What is the primary goal of inhaled recombinant human deoxyribonuclease (DNase) in Cystic Fibrosis treatment?

  • To break down the thick mucus in the respiratory tract (correct)
  • To reduce the production of sweat glands
  • To stimulate pancreatic enzyme secretion
  • To enhance the immune system's response to infections

What is the current median age of death for individuals with Cystic Fibrosis?

<p>Over 30 years of age (C)</p> Signup and view all the answers

What is the percentage of lung cancers attributed to cigarette smoking?

<p>Over 85% of cases (C)</p> Signup and view all the answers

What is the percentage of lung cancers classified as Small Cell Lung Cancer (SCLC)?

<p>25% of lung cancers (A)</p> Signup and view all the answers

What is a common symptom of an abdominal aortic aneurysm?

<p>Sense of fullness (C)</p> Signup and view all the answers

Which of the following factors is associated with thoracic aneurysms?

<p>Syphilis (C)</p> Signup and view all the answers

What is the significance of Grey Turner sign and Cullen sign in the context of abdominal aortic aneurysm?

<p>They are signs of retroperitoneal bleeding, but not very sensitive for ruptured AAA (C)</p> Signup and view all the answers

What is the triad of symptoms indicating a ruptured abdominal aortic aneurysm?

<p>Abdominal pain, hypotension, and a palpable pulsatile abdominal mass (D)</p> Signup and view all the answers

What is the most appropriate management for a patient presenting with the triad of ruptured abdominal aortic aneurysm?

<p>Emergent laparotomy (B)</p> Signup and view all the answers

What is the most common location of pain in patients with abdominal aortic aneurysm?

<p>Hypogastrium and lower back (A)</p> Signup and view all the answers

What is the primary cause of transudative effusions in pleural spaces?

<p>Elevated capillary pressure in visceral or parietal pleura (A)</p> Signup and view all the answers

Which of the following symptoms is most likely due to compression of the esophagus?

<p>Dysphagia (D)</p> Signup and view all the answers

Which nerve is most commonly involved in diaphragm paralysis?

<p>Phrenic nerve (C)</p> Signup and view all the answers

What is the most appropriate next step in the management of an asymptomatic patient with a benign-appearing mass on CT scan?

<p>Close observation (A)</p> Signup and view all the answers

Which of the following is a common complication of a mediastinal mass?

<p>All of the above (D)</p> Signup and view all the answers

What is the diagnostic test of choice for evaluating a mediastinal mass?

<p>Chest CT with IV contrast (B)</p> Signup and view all the answers

What is a possible cause of a 10-fold increase in ALK-P levels?

<p>Intrahepatic cholestasis (B)</p> Signup and view all the answers

What is the most common cause of aperistalsis of esophagus in the United States?

<p>Idiopathic (D)</p> Signup and view all the answers

What is the characteristic of dysphagia in patients with achalasia?

<p>Equal difficulty swallowing solids and liquids (B)</p> Signup and view all the answers

What is the significance of a normal GGT level in a patient with elevated ALK-P levels?

<p>It confirms a bone or intestinal origin of the ALK-P elevation (B)</p> Signup and view all the answers

What is the reason for weight loss in patients with achalasia?

<p>Inability to consume adequate calories due to dysphagia (C)</p> Signup and view all the answers

What is the typical AST-ALT ratio in a patient with abnormal LFTs due to alcohol consumption?

<p>The AST level is always higher than the ALT level (B)</p> Signup and view all the answers

What is the significance of markedly elevated alkaline phosphatase and GGT levels in a patient's LFTs?

<p>It suggests cholestatic LFTs (C)</p> Signup and view all the answers

What is the recommended surveillance measure for patients with achalasia?

<p>Surveillance esophagoscopy (C)</p> Signup and view all the answers

What is the function of the liver reflected by the Prothrombin Time (PT)?

<p>Synthesis of clotting factors (A)</p> Signup and view all the answers

What is the increased risk of esophageal cancer in patients with achalasia?

<p>Sevenfold (C)</p> Signup and view all the answers

What is the common type of esophageal cancer associated with achalasia?

<p>Squamous cell carcinoma (D)</p> Signup and view all the answers

What is a possible cause of a decreased albumin level in a patient?

<p>Chronic liver disease (D)</p> Signup and view all the answers

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