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Questions and Answers
What is the mechanism of action of cyclosporine?
What is the mechanism of action of cyclosporine?
- Inhibition of JAK-STAT signaling pathway
- Depletion of lymphocyte numbers
- Inhibition of calcineurin and inactivation of B-cells
- Inhibition of calcineurin and inactivation of T-cells (correct)
Which of the following is a common adverse effect of cyclosporine?
Which of the following is a common adverse effect of cyclosporine?
- Hypertension and nephrotoxicity (correct)
- Increased risk of venous thrombotic events
- Increased risk of infections
- Bone marrow suppression
How do anticancer drugs like cyclophosphamide and azathioprine work as DMARDs?
How do anticancer drugs like cyclophosphamide and azathioprine work as DMARDs?
- They inhibit calcineurin and inactivate T-cells
- They suppress the bone marrow, leading to immunosuppression
- They deplete the number of lymphocytes, decreasing autoantibody production (correct)
- They inhibit the JAK-STAT signaling pathway
Which of the following statements about baricitinib is correct?
Which of the following statements about baricitinib is correct?
Which of the following is a correct statement about the use of cyclosporine during pregnancy?
Which of the following is a correct statement about the use of cyclosporine during pregnancy?
What is the mechanism of action of mycophenolate mofetil?
What is the mechanism of action of mycophenolate mofetil?
What is the main adverse effect associated with Adalimumab?
What is the main adverse effect associated with Adalimumab?
Which inflammatory diseases has Anakinra been approved to treat?
Which inflammatory diseases has Anakinra been approved to treat?
What is the mechanism of action of Sarilumab?
What is the mechanism of action of Sarilumab?
Which of the following is NOT an adverse effect of IL-6 receptor antagonist (Sarilumab)?
Which of the following is NOT an adverse effect of IL-6 receptor antagonist (Sarilumab)?
What type of drugs are Secukinumab and Baricitinib classified as?
What type of drugs are Secukinumab and Baricitinib classified as?
Which drug inhibits T-cell activation by blocking interaction with CD28 on T cells?
Which drug inhibits T-cell activation by blocking interaction with CD28 on T cells?
What is the main adverse effect associated with Rituximab?
What is the main adverse effect associated with Rituximab?
Which drug has been reported to reactivate hepatitis B?
Which drug has been reported to reactivate hepatitis B?
What is the category of safety during pregnancy for Rituximab?
What is the category of safety during pregnancy for Rituximab?
Which of the following drugs inhibits tumor necrosis factor (TNF-a)?
Which of the following drugs inhibits tumor necrosis factor (TNF-a)?
What is the common role of tumor necrosis factor (TNF-a) inhibitors in terms of risk?
What is the common role of tumor necrosis factor (TNF-a) inhibitors in terms of risk?
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