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What is the active form of cycloserine and what is its mechanism of action?
What is the active form of cycloserine and what is its mechanism of action?
- The (R)-enantiomer does not inhibit the activity of D-alanine racemase, but has psychoactive effects.
- The (S)-enantiomer inhibits the activity of D-alanine racemase, which is essential for the synthesis of bacterial cell walls.
- The (R)-enantiomer inhibits the activity of D-alanine racemase, which is essential for the synthesis of bacterial cell walls. (correct)
- The (S)-enantiomer does not inhibit the activity of D-alanine racemase, but has psychoactive effects.
What are the bond angles between the carbon and nitrogen atoms in the cyclopropane ring of cycloserine?
What are the bond angles between the carbon and nitrogen atoms in the cyclopropane ring of cycloserine?
- Approximately 90 degrees
- Approximately 120 degrees
- Approximately 109.5 degrees (correct)
- Approximately 180 degrees
What is the difference between the two possible stereoisomers of cycloserine?
What is the difference between the two possible stereoisomers of cycloserine?
- They have different configurations of the amino and hydroxyl groups on the cyclopropane ring. (correct)
- They have the same configuration of the amino and hydroxyl groups on the cyclopropane ring.
- They have different chemical formulas.
- They have different mechanisms of action.
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