Cryptosporidium

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Questions and Answers

What is the primary mode of transmission of Cryptosporidium?

  • Through airborne contact
  • Through infected blood transfusion
  • Through direct skin contact
  • Through contaminated water and fecal-oral route (correct)

What is the typical appearance of Cryptosporidium oocysts under staining?

  • Purple-blue under acid fast staining
  • Greenish-blue under Giemsa staining
  • Amethyst-like under acid fast staining (correct)
  • Bright pink under fluorescent staining

Which of the following is NOT a treatment option for Cryptosporidiosis?

  • Spiromycin
  • Metronidazole (correct)
  • Ciprofloxacin
  • Nitazoxanide

What is the primary location where Cryptosporidium parasites attach and cause damage?

<p>Small intestine (A)</p> Signup and view all the answers

What is the primary method of prevention for Cryptosporidiosis?

<p>Filtration of water (B)</p> Signup and view all the answers

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Study Notes

Cryptosporidium Characteristics

  • Causes profound diarrhea in AIDS patients, particularly in immunocompromised individuals, such as those with HIV
  • Unicellular, partially acid-fast, and releases oocytes through feces, which can be absorbed orally

Infection and Transmission

  • Infectious cysts are excreted in watery stool, containing four motile sporozoites that attach to the small intestinal wall, causing damage
  • Oocysts can be transmitted through contaminated water, appearing like amethyst under staining

Diagnosis and Treatment

  • Nitazoxanide is a treatment option for immunocompetent individuals
  • Spiromycin is another treatment option, although not FDA-approved in the US
  • Filtration can be used to remove oocysts from water

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