5 Questions
What is the primary mode of transmission of Cryptosporidium?
Through contaminated water and fecal-oral route
What is the typical appearance of Cryptosporidium oocysts under staining?
Amethyst-like under acid fast staining
Which of the following is NOT a treatment option for Cryptosporidiosis?
Metronidazole
What is the primary location where Cryptosporidium parasites attach and cause damage?
Small intestine
What is the primary method of prevention for Cryptosporidiosis?
Filtration of water
Study Notes
Cryptosporidium Characteristics
- Causes profound diarrhea in AIDS patients, particularly in immunocompromised individuals, such as those with HIV
- Unicellular, partially acid-fast, and releases oocytes through feces, which can be absorbed orally
Infection and Transmission
- Infectious cysts are excreted in watery stool, containing four motile sporozoites that attach to the small intestinal wall, causing damage
- Oocysts can be transmitted through contaminated water, appearing like amethyst under staining
Diagnosis and Treatment
- Nitazoxanide is a treatment option for immunocompetent individuals
- Spiromycin is another treatment option, although not FDA-approved in the US
- Filtration can be used to remove oocysts from water
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