CRISPR
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Questions and Answers

Which type of genetic elements can be disrupted using CRISPR?

  • Non-coding elements only
  • Protein-coding genes only
  • Neither protein-coding genes nor non-coding elements
  • Both protein-coding genes and non-coding elements (correct)

    • What type of genetic variations can be created using CRISPR?

  • Single nucleotide polymorphisms (SNPs) only
  • Both single nucleotide polymorphisms (SNPs) and structural variations (correct)
  • Neither single nucleotide polymorphisms (SNPs) nor structural variations
  • Structural variations only

    • What can CRISPR be used for in the study of gene function?

  • To create gene knock-out or knock-in animals
  • To target and activate/silence specific genes (correct)
  • To generate disease models in animals and human pluripotent stem cells
  • To study the physiological role of genetic variations

    • Which genetic elements can be disrupted using CRISPR?

    <p>Both protein-coding genes and non-coding elements</p> Signup and view all the answers

    What types of genetic variations can be created using CRISPR?

    <p>Both SNPs and structural variations</p> Signup and view all the answers

    What can CRISPR be modified to do in order to study gene function?

    <p>Create gene knock-in animals and bypass the use of embryonic stem cells</p> Signup and view all the answers

    What is the advantage of injecting CRISPR directly into one-cell stage embryos?

    <p>It bypasses the use of embryonic stem cells</p> Signup and view all the answers

    What can CRISPR be used for in the study of gene function?

    <p>Both drug target validation and preclinical drug tests</p> Signup and view all the answers

    What is the purpose of using CRISPR to create gene knock-out or knock-in animals?

    <p>To study the physiological role of genetic variations</p> Signup and view all the answers

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