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What is one of the main purposes of sentencing according to the Criminal Justice Act 2003?
What is one of the main purposes of sentencing according to the Criminal Justice Act 2003?
Which theory emphasizes that punishment should reflect the severity of the crime committed?
Which theory emphasizes that punishment should reflect the severity of the crime committed?
What does Durkheim's expressive view of punishment suggest?
What does Durkheim's expressive view of punishment suggest?
What does the theory of retribution focus on?
What does the theory of retribution focus on?
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Which of the following best describes the general deterrence concept?
Which of the following best describes the general deterrence concept?
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What outcome does the just deserts theory imply for the victim of a crime?
What outcome does the just deserts theory imply for the victim of a crime?
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In the context of punishment, what does incapacitation aim to achieve?
In the context of punishment, what does incapacitation aim to achieve?
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What does the concept of reparation in punishment focus on?
What does the concept of reparation in punishment focus on?
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What is a primary symptom associated with excessive dopamine activity in schizophrenia?
What is a primary symptom associated with excessive dopamine activity in schizophrenia?
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Which dopaminergic pathway is primarily involved in schizophrenia?
Which dopaminergic pathway is primarily involved in schizophrenia?
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How does PCP support the glutamate hypothesis in schizophrenia?
How does PCP support the glutamate hypothesis in schizophrenia?
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What is a limitation of the dopamine hypothesis regarding antipsychotic drugs?
What is a limitation of the dopamine hypothesis regarding antipsychotic drugs?
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Which gene is primarily associated with immune and inflammatory responses related to neurodegeneration?
Which gene is primarily associated with immune and inflammatory responses related to neurodegeneration?
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Which condition is characterized by disorganized symptoms rather than primarily psychotic symptoms?
Which condition is characterized by disorganized symptoms rather than primarily psychotic symptoms?
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What role does the TP53 gene play in relation to schizophrenia?
What role does the TP53 gene play in relation to schizophrenia?
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What is the relationship between dopamine and glutamate in the context of schizophrenia?
What is the relationship between dopamine and glutamate in the context of schizophrenia?
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How does the hTPH2 mutation affect individuals with major depression?
How does the hTPH2 mutation affect individuals with major depression?
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What is one of the main effects of May on individuals during stressful events?
What is one of the main effects of May on individuals during stressful events?
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Which type of antidepressant drug works by blocking reabsorption of neurotransmitters?
Which type of antidepressant drug works by blocking reabsorption of neurotransmitters?
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What characterizes orchid and dandelion children in the context of environmental sensitivity?
What characterizes orchid and dandelion children in the context of environmental sensitivity?
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Why might depressed patients with the hTPH2 mutation not respond to certain antidepressants?
Why might depressed patients with the hTPH2 mutation not respond to certain antidepressants?
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What distinguishes psychotic symptoms from disorganized symptoms in schizophrenia?
What distinguishes psychotic symptoms from disorganized symptoms in schizophrenia?
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Which of the following describes positive symptoms of schizophrenia?
Which of the following describes positive symptoms of schizophrenia?
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What role do stress hormones play in the orchid and dandelion model?
What role do stress hormones play in the orchid and dandelion model?
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What distinguishes tricyclic antidepressants from other types?
What distinguishes tricyclic antidepressants from other types?
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What is one of the factors that can influence the development of schizophrenia?
What is one of the factors that can influence the development of schizophrenia?
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What is a common feature of medications used to treat psychiatric disorders?
What is a common feature of medications used to treat psychiatric disorders?
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Which statement about the treatment of negative symptoms in schizophrenia is accurate?
Which statement about the treatment of negative symptoms in schizophrenia is accurate?
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What is a common gender-related characteristic of schizophrenia prevalence?
What is a common gender-related characteristic of schizophrenia prevalence?
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How do monozygotic twins' concordance rates for schizophrenia compare to dizygotic twins?
How do monozygotic twins' concordance rates for schizophrenia compare to dizygotic twins?
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Which of the following genes is associated with serotonin transporter functions relevant to schizophrenia?
Which of the following genes is associated with serotonin transporter functions relevant to schizophrenia?
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Which neurotransmitter system is primarily implicated in genetic influences related to schizophrenia?
Which neurotransmitter system is primarily implicated in genetic influences related to schizophrenia?
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Study Notes
Aims of Punishment
- Punishment is a key aspect of the criminal justice system, ensuring consequences for crime and upholding societal order.
- The Criminal Justice Act 2003 (s142) outlines two main aims of sentencing:
- Punishment of the offender: Holding the offender accountable for their actions.
- Reduction of crime: Deterrence, rehabilitation, and incapacitation are all aimed at reducing crime.
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Retribution, often described as "an eye for an eye", is about justice and making the offender suffer in proportion to the harm caused.
- This approach sees punishment as deserving and a consequence of the crime, reflecting society's outrage.
- Just Deserts theory by Von Hirsch emphasizes that punishment should be proportionate to the crime and express blame or censure, addressing the wrong done to the victim.
Deterrence
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General Deterrence: Aims to discourage potential offenders by demonstrating the consequences of criminal behavior.
- This is achieved by making punishment public and visible, serving as a warning to the public.
- Individual Deterrence: Aiming to prevent the specific offender from reoffending by making them experience the unpleasant consequences of their actions.
Incapacitation (Public Protection)
- This aim focuses on removing the offender from society to protect the public while they are incapacitated.
- This can involve imprisonment, restraining orders, or other measures to prevent further harm.
Reparation
- This aims to address the harm caused by the offender and restore the victim's sense of justice.
- Reparation can involve various measures like:
- Financial compensation: Repaying the victim for damages or losses.
- Community service: Performing work to benefit the community, demonstrating responsibility and acknowledging the impact of their actions.
- Apology: A sincere expression of remorse and regret for the harm caused.
Scenario Analysis
- In the scenario provided, the offender, an 18-year-old male, broke into a garage, causing property damage and causing emotional unease to the victim.
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Reparation would be the most appropriate aim in this case, focusing on restoring the victim's sense of justice:
- The offender could be ordered to make financial compensation for the damage to the garage and fence.
- Community service could be used to benefit the local community and demonstrate responsibility.
- A sincere apology to the victim should be encouraged, acknowledging the harm caused and expressing regret.
Schizophrenia
- Affects about 1% of the population with varying severity
- Occurs across the globe, but is significantly more prevalent in the US and Europe compared to third world countries
- Prevalence is slightly higher in men than women with an estimated 7:5 ratio
- Men experience more severe symptoms and an earlier onset (early 20s versus late 20s)
Positive and Negative Symptoms
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Positive symptoms are behaviours present that should be absent
- Psychotic (e.g., hallucinations, delusions)
- Disorganized (e.g., disorganized speech and behaviour)
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Negative symptoms are behaviours absent that should be present
- Weak social interaction
- Diminished emotional expression
- Limited speech
- Impaired working memory
- Negative symptoms are generally stable over time and difficult to treat
Heredity
- Twin studies suggest a genetic factor, but not attributed to a single gene
- Monozygotic (identical) twins have a significantly higher concordance rate (agreement) than dizygotic (fraternal) twins
- However, even monozygotic twins only have a 50% concordance rate
- This suggests other factors contribute to the development of Schizophrenia
- Observed differences between dizygotic twins compared to siblings suggest potential prenatal or postnatal environmental influences
Genes Associated with Schizophrenia
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Neurotransmission
- Dopamine receptors: DRD1, DRD2, DRD4
- Serotonin production: TPH1
- Serotonin transporter: SLC6A4
- NMDA glutamate receptor function: DAO, GRIN2B
- Glutamate release: DTNBP1
- GABAA receptor: GABRB2
- Enzyme that deactivates neurotransmitters (e.g., dopamine): COMT
Gene-Environment Interaction
- Individuals exhibit varying susceptibility to both negative (risk-provoking) and positive (development-enhancing) environmental conditions
- Some individuals may experience higher sickness leave due to poor environments than others in similar conditions
- Potential contributing factors include:
- Stress hormones
- Neuro-plasticity
Tryptophan Hydroxylase-2 (hTPH2)
- A specific mutation in the hTPH2 gene is found ten times more frequently in major depression patients compared to non-depressed individuals
- This mutation results in a dysfunctional protein, causing an approximately 80% loss of function in serotonin production
- Depressed patients with this gene mutation may not respond to antidepressants that work by blocking serotonin reuptake, as insufficient serotonin is produced
Antidepressant Drugs
- Many psychiatric medication discoveries were accidental
- Categories of antidepressants include:
- Tricyclics
- Selective serotonin reuptake inhibitors (SSRIs)
- Monoamine oxidase inhibitors (MAOIs)
- Atypical antidepressants
Tricyclic Antidepressants
- Block transporter proteins responsible for reabsorbing serotonin, dopamine, and noradrenaline back into the presynaptic neuron after release
- Example: Imipramine (Tofranil)
- Also block histamine receptors, acetylcholine receptors, and certain sodium channels
The Dopamine Hypothesis
- Schizophrenia is associated with excessive dopamine activity in the brain
- Supporting Evidence: Amphetamine overdose causes psychotic behaviour nearly indistinguishable from Schizophrenia, including hallucinations and paranoid delusions, by increasing dopaminergic activity
- Research indicates increased activity specifically at the D2 receptor
Limitations of the Dopamine Hypothesis
- Direct measurement of dopamine and its metabolites generally show normal levels in people with Schizophrenia
- Antipsychotic drugs block dopamine quickly, within minutes, but their behavioural effects take much longer, building gradually over 2 to 3 weeks
Dopaminergic Pathways in the Brain
- Mesolimbocortical System: A set of neurons that project from the midbrain tegmentum to the limbic system
The Glutamate Hypothesis
- Schizophrenia is partially attributed to deficient activity at glutamate receptors, particularly in the prefrontal cortex
- In many brain areas, dopamine inhibits glutamate release, or glutamate stimulates neurons that inhibit dopamine release
- This implies increased dopamine can have effects similar to decreased glutamate
Glutamate Hypothesis Supporting Evidence
- Lower than normal glutamate release and fewer receptors observed in the prefrontal cortex and hippocampus of individuals with Schizophrenia
- Phencyclidine (PCP), a drug that acts as an NMDA receptor antagonist (blocking its activity), supports the glutamate hypothesis
- PCP-induced behavioural effects are similar to those seen in Schizophrenia, suggesting a potential role of NMDA receptor dysfunction
Genes Associated with Schizophrenia (continued)
-
Development
- Enzymes involved in neural development: MTHFR
- Axon guidance: PLXNA2
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Neural Damage
- Neurodegeneration: APOE
- Immune and inflammatory responses: IL1B, HP
- Gene mutation prevention: TP53
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Description
Explore the Aims of Punishment outlined in the Criminal Justice Act 2003, including the concepts of punishment, deterrence, and retribution. Understand how these principles function to maintain societal order and hold offenders accountable for their actions. Dive into theories like Just Deserts and the impact of deterrence on crime reduction.