10 Questions
Which enzyme catalyzes the synthesis of creatine?
GAMT
What is the primary function of l-arginine:glycine amidinotransferase (AGAT)?
To form guanidinoacetate for energy production in muscle contraction
Which molecule accounts for the methyl group provided by S-adenosylmethionine (SAM)?
Methionine
How is creatine transported to other tissues such as muscle?
Mediated by the creatine transporter through secondary active transport by sodium/chloride-ATPase generated gradient
What is formed when creatine phosphate loses a phosphoric acid and then loses water?
Creatinine
What is the primary source of creatinine in the body?
Breakdown of creatine phosphate in muscle
What is the relationship between plasma creatinine and glomerular filtration rate (GFR)?
Inversely related
Why is plasma creatinine considered a more reliable screening test for renal function than Blood Urea Nitrogen (BUN)?
Less influenced by diet and hydration
What does creatinine clearance measure?
The amount of creatinine eliminated from the blood by the kidneys
What is Glomerular Filtration Rate (GFR) used to gauge?
Renal function
Test your knowledge of clinical chemistry with this quiz on creatinine determination. Learn about specimen collection, biochemistry, methods, pathophysiology, materials, and reagents. Dive into the experiment procedure and reference interval computation.
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