Physiology of Creatinine and Creatine Phosphate
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Questions and Answers

What high-energy compound is created through phosphorylation in various organs, muscles, and the brain?

  • Creatinine
  • Guanosine diphosphate (GDP)
  • Creatine phosphate (correct)
  • Adenosine triphosphate (ATP)
  • What can cause an increase in daily creatinine excretion?

  • Vegetarian diet
  • Low muscle mass
  • Increased dietary intake of creatinine (correct)
  • Reduced protein intake
  • Which organ primarily removes creatinine from the blood?

  • Kidneys (correct)
  • Heart
  • Lungs
  • Liver
  • Why do men tend to have higher concentrations of creatinine than women?

    <p>Lower muscle mass in men</p> Signup and view all the answers

    What is the main role of creatine kinase (CK-MB) in blood plasma?

    <p>Indicating tissue damage</p> Signup and view all the answers

    Which compound acts as a high-energy reserve in a coupled reaction involving the regeneration of ATP?

    <p>Phosphocreatine</p> Signup and view all the answers

    What is the primary biological source for the production of creatinine?

    <p>Glycocyamine</p> Signup and view all the answers

    In tissues with high, fluctuating energy demands like muscle and brain, which molecule plays an important role due to its ability to quickly regenerate ATP?

    <p>Phosphocreatine</p> Signup and view all the answers

    What is the function of creatine phosphate in the body?

    <p>Acting as a reserve of high-energy phosphates in muscles and the brain</p> Signup and view all the answers

    Which enzyme catalyzes the conversion of arginine and glycine into guanidinoacetate in the kidneys?

    <p>AGAT</p> Signup and view all the answers

    Where is nonphosphorylated creatine released into after it is formed?

    <p>Blood by the liver</p> Signup and view all the answers

    What is the role of creatine phosphate in recycling ATP?

    <p>Serving as a reserve of high-energy phosphates for ATP production</p> Signup and view all the answers

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