Cranial Cavity & CSF Quiz

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Questions and Answers

What type of aphasia is associated with damage to the Left MCA Superior Division?

  • Anomic aphasia
  • Wernicke’s aphasia
  • Broca’s aphasia (correct)
  • Global aphasia

What is a common sensory deficit associated with the Left MCA Inferior Division?

  • No sensory deficits
  • Sensory loss in the left face and leg
  • Sensory loss in the right face and arm (correct)
  • Sensory gain in the right arm

Which artery is responsible for feeding the parasylvian zone?

  • Anterior cerebral artery
  • Basilar artery
  • Middle cerebral artery (correct)
  • Internal carotid artery

What is a likely consequence of occlusion of the posterior cerebral artery (PCA)?

<p>Homonymous hemianopia (B)</p> Signup and view all the answers

What type of weakness is caused by damage to the Left MCA Stem?

<p>Severe weakness or paralysis of the right face, arm, and leg (B)</p> Signup and view all the answers

What is the role of acetylcholine in the body?

<p>It facilitates muscle contraction. (A)</p> Signup and view all the answers

What is the primary function of norepinephrine in the nervous system?

<p>To enhance attention and vigilance. (A)</p> Signup and view all the answers

What is meant by the term 'hyperpolarization' in a neuron?

<p>Influx of negatively charged ions. (A)</p> Signup and view all the answers

Which neurotransmitter is considered the major inhibitory neurotransmitter?

<p>GABA (C)</p> Signup and view all the answers

What is necessary to change a neuron's resting potential?

<p>An adequate stimulus. (A)</p> Signup and view all the answers

Which process describes a single action potential triggering multiple excitatory postsynaptic potentials?

<p>Divergence (C)</p> Signup and view all the answers

What happens to a neuron at its resting potential?

<p>It is balanced and stable. (C)</p> Signup and view all the answers

Which neurotransmitter is known for its role in mood enhancement?

<p>Serotonin (C)</p> Signup and view all the answers

What is the main function of myelin in the nervous system?

<p>To insulate axons and increase the speed of impulse transmission (D)</p> Signup and view all the answers

Which term describes neurons that transmit signals from sensory receptors to the central nervous system (CNS)?

<p>Sensory neurons (C)</p> Signup and view all the answers

What is the role of neurotransmitters in the synapse?

<p>To transmit and receive signals across the synaptic gap (D)</p> Signup and view all the answers

Which structural class of neurons has multiple processes extending from the cell body?

<p>Multipolar neurons (A)</p> Signup and view all the answers

What is a neuromuscular junction?

<p>The interface where motor neurons communicate with muscle fibers (B)</p> Signup and view all the answers

Which of the following tracts is NOT recognized as part of the Indirect Activation Pathway?

<p>Corticospinal tract (C)</p> Signup and view all the answers

What type of information is essential for the cerebellum to effectively function within the motor system?

<p>Position sense and motor plan copy (B)</p> Signup and view all the answers

Which of the following is NOT a common sign of cerebellar damage?

<p>Apraxia (B)</p> Signup and view all the answers

What is the primary characteristic of dysarthria?

<p>Poor articulation of speech sounds (A)</p> Signup and view all the answers

Which disorder is characterized by difficulty in performing rapid, alternating movements?

<p>Dysdiadochokinesia (A)</p> Signup and view all the answers

Reduced spontaneous movements on the left side may indicate which condition?

<p>Hemiparesis (B)</p> Signup and view all the answers

Which disorder is caused by damage to the posterior parietal cortex?

<p>Apraxia (D)</p> Signup and view all the answers

What role does the left hemisphere serve in most individuals?

<p>Dominant language hemisphere (C)</p> Signup and view all the answers

What does diaschisis refer to in the context of brain function?

<p>A sudden change in function in a portion of the brain connected to a damaged area (A)</p> Signup and view all the answers

Which of the following statements is true regarding axonal regeneration?

<p>CNS axons do not spontaneously regenerate after injury (A)</p> Signup and view all the answers

Which condition is characterized by the degeneration of myelin on axons?

<p>Multiple Sclerosis (MS) (B)</p> Signup and view all the answers

What role does sensory information play in skilled motor acts such as speech and swallowing?

<p>It influences motor activity and is required for execution (D)</p> Signup and view all the answers

Where are the afferent projections of sensory information first processed?

<p>In the unimodal cortex (A)</p> Signup and view all the answers

What type of sensory receptor is responsible for sensing external stimuli like sight and smell?

<p>Exteroceptors (C)</p> Signup and view all the answers

What is the main consequence of a cerebrovascular accident (CVA)?

<p>Interruption of blood flow leading to neuronal damage (B)</p> Signup and view all the answers

Which of the following is true about Myasthenia Gravis (MG)?

<p>It is a chronic autoimmune disorder affecting neuromuscular junctions (A)</p> Signup and view all the answers

What is the function of the optic chiasm?

<p>To decussate some visual nerve fibers (C)</p> Signup and view all the answers

What is a consequence of injury to the optic nerve?

<p>Complete blindness in one eye (B)</p> Signup and view all the answers

Where do the optic tracts in the CNS terminate?

<p>Thalamus (C)</p> Signup and view all the answers

What is homonymous hemianopia?

<p>Loss of half of the visual field on the same side of both eyes (A)</p> Signup and view all the answers

Which cranial nerve is associated with hearing?

<p>Cranial Nerve VIII (D)</p> Signup and view all the answers

What role does the cerebellum play in voluntary movement?

<p>It is involved in balance and coordination (D)</p> Signup and view all the answers

Which part of the motor system is responsible for organizing motor movements such as reflexes?

<p>Brainstem (B)</p> Signup and view all the answers

What happens to visual information from the left ear after it is processed?

<p>It crosses over to the right hemisphere (A)</p> Signup and view all the answers

Flashcards

Left MCA Superior Division Motor Deficit

Weakness or paralysis of the right face and arm due to upper motor neuron damage.

Left MCA Superior Division Sensory Deficit

Sensory loss in the right face and arm.

Left MCA Superior Division Language/Cognition

Broca's aphasia.

Left MCA Inferior Division Motor Deficit

Minimal or no motor deficits.

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Left MCA Inferior Division Sensory Deficit

Sensory loss in the right face and arm.

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Left MCA Inferior Division Language/Cognition

Wernicke's aphasia.

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Left MCA Inferior Division Visual Deficit

Right visual field deficit (homonymous hemianopia).

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Left MCA Stem Motor Deficit

Severe weakness or paralysis of the right face, arm, and leg (hemiplegia).

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Left MCA Stem Sensory Deficit

Sensory loss right face, arm, and leg.

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Left MCA Stem Language/Cognition

Global aphasia

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Left MCA Stem Visual Deficit

Right homonymous hemianopia.

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Posterior Blood Supply Source

Vertebral arteries.

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Anterior Blood Supply Source

Internal carotid arteries.

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Middle Cerebral Artery Function

Feeds the parasylvian zone.

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Basilar Artery Occlusion Effect

Decreases blood supply to cerebellar arteries.

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PCA Occlusion Impact

Damage to occipital pole & inferolateral surface of brain hemispheres.

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Circle of Willis Location

Located at the base of the brain.

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Unipolar Neuron

A neuron with only one process extending from the cell body.

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Bipolar Neuron

A neuron with two processes extending from the cell body – one axon and one dendrite.

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Multipolar Neuron

A neuron with multiple processes extending from the cell body – one axon and multiple dendrites.

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Pseudounipolar Neuron

A neuron with one process that splits into two branches, functioning as a single axon.

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Sensory Neuron

A neuron that transmits sensory information from receptors to the central nervous system (CNS).

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Motor Neuron

A neuron that transmits motor commands from the CNS to muscles and glands.

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Interneuron

A neuron that connects sensory and motor neurons within the CNS.

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Neuron Cell Body

Part of a neuron containing the nucleus and organelles.

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Axon

The part of a neuron that transmits electrical impulses.

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Dendrite

The part of a neuron that receives signals.

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Myelin

Fatty substance insulating axons for rapid signal transmission.

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Synapse

Junction between two neurons for neurotransmitter communication.

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Neuromuscular Junction

Synapse between a motor neuron and a muscle fiber, triggering muscle contraction.

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Neurotransmitter

Chemical messenger transmitting signals between neurons or to a target cell.

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Inhibitory Neurotransmitter

Reduces the likelihood of an action potential in the receiving neuron.

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Excitatory Neurotransmitter

Increases the likelihood of an action potential in the receiving neuron.

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Acetylcholine (Ach)

A neurotransmitter involved in muscle contraction.

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Dopamine

Neurotransmitter linked to pleasure, reward, and certain mental illnesses like schizophrenia and Parkinson's disease.

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Norepinephrine

A neurotransmitter involved in attention, arousal, and concentration, mainly in the peripheral nervous system.

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Serotonin

A neurotransmitter important for sleep, arousal, and mood.

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GABA

A major inhibitory neurotransmitter, used in treating anxiety and epilepsy.

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Glutamate

A major excitatory neurotransmitter.

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Most prevalent neurotransmitters

GABA and glutamate.

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Neuron function

To transmit information throughout the body.

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Neuron function dependence

On water content and electrical properties for normal function.

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Resting potential

A neuron is not firing impulses but is balanced and steady.

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Change in resting potential

Requires adequate stimulus altering the balance across the membrane.

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Depolarization

Positive ion influx, triggering action potential.

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Action Potential

Electrical impulse traveling along the axon.

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Hyperpolarization

Negative ion influx, making the inside more negative, reducing action potential likelihood.

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Divergence

One action potential triggers multiple excitatory signals.

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Convergence

Many neurons contribute to a single neuron’s signal.

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Indirect Activation Pathway

Pathways connecting subcortical, cerebellar, and brainstem nuclei to lower motor neurons (LMNS) and some cranial nerves.

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Cerebellar Function

The cerebellum uses position sense and motor plan information to coordinate and refine movements.

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Cerebellar Damage Signs

Damage can cause ataxia (incoordination), dysmetria (movement errors), intention tremor, dysdiadochokinesia (trouble with rapid movements), hypotonia (low muscle tone), nystagmus (eye movement), gait abnormalities, and dysarthria (speech impairment).

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Apraxia

A motor disorder characterized by difficulty planning movements in response to a command.

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Dysarthria

A motor speech disorder caused by problems in the motor-speech system, leading to poor articulation of sounds.

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Left Hemisphere Dominance

In most people, the left hemisphere is the dominant center for language processing.

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Hemiparesis

Reduced spontaneous movements on one side of the body.

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Right Hemisphere Damage

Injury to the right hemisphere can lead to visuospatial impairments, affecting the understanding of a picture, or ignoring one side of space.

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Aphasia

Language disorder resulting from left-hemisphere damage.

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Diaschisis

Sudden change in function in a brain area connected to a damaged, distant area.

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Axonal Regeneration (CNS)

CNS axons do not regenerate after injury.

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Axonal Regeneration (PNS)

PNS axons readily regenerate after injury.

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Primary Neuronal Loss

Direct cell death at the site of injury.

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Secondary Neuronal Loss

Neuron death after initial injury and is caused by multiple things.

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Multiple Sclerosis (MS)

Widespread disease, myelin degeneration on axons.

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Parkinson’s Disease (PD)

Basal ganglia disorder, dopamine deficiency.

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Myasthenia Gravis (MG)

Autoimmune disorder, neuromuscular junction degeneration.

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Amyotrophic Lateral Sclerosis (ALS)

Progressive neurodegenerative disease, motor neuron loss.

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Cerebrovascular Accident (CVA)

Stroke, interrupted blood flow causing neuronal damage.

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Sensory Information (Speech)

Crucial for speech production and perception, execution of actions.

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Sensory Receptor

Nerve ending, sends signals to the brain when stimulated.

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Exteroceptors

Sensory receptors in skin responding to external stimuli.

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Proprioceptors

Sensory receptors in muscles and joints sensing body position/movement.

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Interoceptors

Sensory receptors in internal organs, sensing internal stimuli.

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Unimodal Cortex

First processing area for afferent sensory information.

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Optic Nerve Function

Converts light into neural signals at the back of the eye.

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Optic Chiasm

Point where some optic nerve fibers cross over to the opposite side of the brain.

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Optic Chiasm Injury

Causes loss of peripheral vision in both eyes.

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Optic Nerve Cranial Nerve

Cranial nerve II.

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Optic Tract

Visual fibers in the central nervous system ending at the thalamus.

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Optic Radiations

Visual fibers projecting from thalamus to visual cortices.

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Optic Radiations Damage Location

Possible damage locations include the temporal lobe, parietal lobe, optic chiasm, or optic tracts.

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Homonymous Hemianopia

Loss of half of the visual field on the same side of both eyes.

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Homonymous Hemianopia Damage

Damage to the optic tract, optic radiation, or occipital lobe.

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Complete Blindness in One Eye

Signifies damage to the optic nerve.

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Auditory Nerve Cranial Nerve

Cranial nerve VIII.

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Auditory Pathway

Cochlea (sensory hair cells) → NTs stimulate CN VIII → cochlear nucleus → auditory cortex

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Primary Auditory Cortex

Heschl's gyrus.

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Voluntary Movement Control Systems

Pyramidal system, extrapyramidal system, and cerebellum.

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Spinal Cord (Motor)

Executes low-level demands generating muscle forces.

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Brainstem (Motor)

Organizes motor movements, like reflexes and fine motor movements.

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Study Notes

Blood Supply & Protection

  • The inner surface of the cranial vault is divided into fossae
  • Anterior: frontal lobes
  • Middle: temporal lobes
  • Posterior: cerebellum and brainstem
  • Three layers of tissue cover the brain and spinal cord
    • Pia mater (deepest)
    • Arachnoid mater
    • Dura mater (superficial)
  • Dura mater divides the cranial cavity into cerebral subdivisions, limiting infection/hemorrhage spread
  • Ventricles are interconnected cavities that produce and contain cerebrospinal fluid (CSF)
  • There are four ventricles
    • Two lateral ventricles, one in each cerebral hemisphere
    • Third ventricle, midline between the two cerebral hemispheres
    • Fourth ventricle, between the brainstem and cerebellum
  • Lateral ventricles connect to the third ventricle via interventricular foramina (Monro)
  • The third ventricle connects to the fourth ventricle via the cerebral aqueduct (Sylvius).
  • Choroid plexus within the ventricles produce CSF, which protects and nourishes the brain and spinal cord

Neuronal Function

  • Structural Classes of Nerve Cells
    • Unipolar: one process
    • Bipolar: two processes (one axon, one dendrite)
    • Multipolar: multiple processes (one axon, multiple dendrites)
    • Pseudounipolar: one process that splits
  • Functional Classes of Nerve Cells
    • Sensory (Afferent): transmit sensory signals
    • Motor (Efferent): transmit motor commands
    • Interneurons: connect sensory and motor within CNS
  • Basic Parts of a Neuron
    • Cell body: contains nucleus and organelles
    • Axon: transmits electrical impulses
    • Dendrites: receive signals
  • Myelin: white, fatty substance that insulates axons, enabling rapid transmission
  • Synapse: junction between neurons, where communication occurs via neurotransmitters
  • Neuromuscular Junction: synapse between a motor neuron and a muscle fiber
  • Neurotransmitters: chemical messengers that transmit signals across synapses

Neurosensory Organization

  • Sensory receptors are nerve endings that signal the central nervous system (CNS) upon stimulation
  • Three broad classes of sensory receptors:
    • Exteroceptors: detect external stimuli
    • Proprioceptors: detect body position and movement
    • Interoceptors: sense internal stimuli
  • Sensory information is processed first in the unimodal cortex (primary sensory cortex)
  • Sensory input modalities: visual, auditory, tactile (somatosensory)
  • Anterolateral system carries pain, temperature, light touch, pressure, and tactile location
  • Dorsal Column-Medial Lemniscus (DCML) system conveys proprioceptive sensation
  • Somatosensory information: ability to determine joint position without visual feedback

Motor System Organization & Disorders

  • Three main neural systems control voluntary movement:
    • Pyramidal system
    • Extrapyramidal system
    • Cerebellum
  • Spinal cord, brainstem, cerebellum, basal ganglia, limbic system, internal capsule/corona radiations, and cortex contribute to motor actions.
  • Pyramidal system: corticospinal, corticonuclear, corticopontine tracts
  • Extrapyramidal system: indirect activation pathway, regulating reflexes and maintaining posture/tone
  • Cerebellum: coordination, error detection/correction, ongoing monitoring of proprioception

Other

  • Left Hemisphere: typically dominant for language
  • Hemiparesis: reduced spontaneous movements on one side of the body
  • Homonymous hemianopia: loss of half of the visual field in both eyes
  • Aphasia: language disorder due to left-hemisphere damage
  • Cerebellar Damage: ataxia, dysmetria, intention tremor, dysdiadochokinesia, hypotonia, nystagmus, gait abnormalities, speech disturbances
  • Apraxia: motor planning difficulties from posterior parietal cortex damage
  • Dysarthria: motor speech disorder due from injury to the motor component of the speech system

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