COVID-19 Treatment and Prophylaxis Quiz
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Questions and Answers

Which of the following is NOT a component of fungal cell walls?

  • Ergosterol (correct)
  • Mannoproteins
  • Glucan
  • Chitin
  • Which of the following is a characteristic of yeast fungi?

  • They are region-specific
  • They can be mold or yeast (correct)
  • They are multicellular
  • They contain chitin in their cell walls
  • Which of the following types of fungal infections primarily affect the skin and soft tissues?

  • Cryptococcus
  • Candida (correct)
  • Histoplasma
  • Aspergillus
  • Which azole antifungal requires a loading dose?

    <p>Posaconazole</p> Signup and view all the answers

    Which azole antifungal has the highest bioavailability?

    <p>Fluconazole</p> Signup and view all the answers

    Which azole antifungal has activity against Candida glabrata?

    <p>Fluconazole</p> Signup and view all the answers

    Which azole antifungal is available as an extended-release oral suspension?

    <p>Posaconazole</p> Signup and view all the answers

    Which of the following is the best protection against influenza?

    <p>Annual vaccination</p> Signup and view all the answers

    Which of the following is NOT a risk factor for increased complications from influenza?

    <p>Being a healthcare worker</p> Signup and view all the answers

    Which of the following drugs is NOT an influenza antiviral?

    <p>Amantadine</p> Signup and view all the answers

    Which of the following is a potential side effect of Zanamivir?

    <p>Bronchospasm</p> Signup and view all the answers

    Which of the following is a risk factor for severe respiratory syncytial virus (RSV) infection?

    <p>Having a congenital heart disease</p> Signup and view all the answers

    What is the mortality rate like for children under 2 years with RSV infection?

    <p>Higher in developing countries</p> Signup and view all the answers

    What is the mechanism of action of palivizumab?

    <p>Interacting with RSV F-protein to prevent serious LRTIs</p> Signup and view all the answers

    Which of the following antifungal agents is primarily administered intravenously and can cause nephrotoxicity?

    <p>Amphotericin B</p> Signup and view all the answers

    Which antifungal agent is associated with minimal systemic absorption and is commonly used topically?

    <p>Nystatin</p> Signup and view all the answers

    Which of the following antifungal agents is a pro-drug and is renally excreted?

    <p>Voriconazole</p> Signup and view all the answers

    Which second generation triazole antifungal agent has a broad spectrum of activity against Candida spp. and Aspergillus spp.?

    <p>Voriconazole</p> Signup and view all the answers

    Which antifungal agent is indicated for the treatment of ringworm infections of the hair, skin, and nails?

    <p>Griseofulvin</p> Signup and view all the answers

    Which antifungal agent inhibits fungal squalene epoxidase to decrease sterol formation?

    <p>Terbinafine</p> Signup and view all the answers

    Which investigational agent targets the Gwt1 fungal enzyme and blocks the glycosylphosphatidylinositol biosynthesis pathway?

    <p>APX001A-Fosmanogepix</p> Signup and view all the answers

    Which investigational agent is an oral dihydroorotate dehydrogenase enzyme inhibitor that blocks pyrimidine synthesis?

    <p>Olorofim</p> Signup and view all the answers

    Which drug is indicated for the treatment of COVID-19 by inhibiting viral replication through binding to RNA-dependent RNA polymerase?

    <p>Remdesivir</p> Signup and view all the answers

    Which drug is a corticosteroid used for the treatment of COVID-19, with multiple mechanisms of action including inhibition of viral protease and promotion of anti-inflammatory genes?

    <p>Dexamethasone</p> Signup and view all the answers

    Which drug is an investigational agent being studied for the treatment of COVID-19 by inhibiting the 3CLpro protease?

    <p>Shionogi Protease Inhibitor (S-217622)</p> Signup and view all the answers

    Which drug is an investigational agent used for the treatment of severe COVID-19 cases, administered within 48 hours of mechanical ventilation or extracorporeal membrane oxygenation?

    <p>Vilobelimab</p> Signup and view all the answers

    Study Notes

    COVID-19 Treatment and Prophylaxis Options

    • Baloxavir is an antiviral drug used for the treatment and prophylaxis of influenza, but not recommended for COVID-19.
    • Remdesivir is an adenosine analog that inhibits viral replication by binding to RNA-dependent RNA polymerase, and is indicated for the treatment of COVID-19.
    • Dexamethasone is a corticosteroid that has multiple mechanisms of action, including inhibition of viral protease and promotion of anti-inflammatory genes. It is used for the treatment of COVID-19.
    • Tocilizumab is a JAK-1 inhibitor that targets IL-6 receptors and is used to treat cytokine release syndrome in severe COVID-19 cases.
    • Baricitinib is another JAK-1 inhibitor that inhibits viral entry and modulates immune cell function. It is used for the treatment of COVID-19.
    • Paxlovid is a combination of nirmatrelvir and ritonavir, which are protease inhibitors. It is used for the treatment of COVID-19.
    • Molnupiravir interferes with viral RNA-dependent RNA polymerase and inhibits viral replication. It is used for the treatment of COVID-19.
    • Monoclonal antibodies are used to prevent the attachment, fusion, and replication of the virus. They are mainly used for mild-moderate cases of COVID-19.
    • Shionogi Protease Inhibitor (S-217622) is an investigational agent that inhibits the 3CLpro protease. It is being studied for the treatment of COVID-19.
    • Vilobelimab is an investigational agent used for the treatment of severe COVID-19 cases, administered within 48 hours of mechanical ventilation or extracorporeal membrane oxygenation.
    • Ribavirin, interferon beta-1b, zinc, vitamin C, vitamin D, and ivermectin are not recommended for the treatment of COVID-19.
    • Pfizer-BioNTech is a COVID-19 vaccine that requires a bivalent booster and is administered in a specific dosage.

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    Description

    Test your knowledge on COVID-19 treatment and prophylaxis options with this informative quiz. Learn about antiviral drugs, corticosteroids, monoclonal antibodies, investigational agents, and more. Discover which treatments are recommended and which are not for COVID-19. Stay informed and make informed decisions about your health.

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