Podcast
Questions and Answers
What is the mechanism of action of Anticholinergics bronchodilators?
What is the mechanism of action of Anticholinergics bronchodilators?
- Non-competitive antagonists of Ach at the nicotinic receptor
- Non-competitive agonists of Ach at the nicotinic receptor
- Competitive agonists of Ach at the muscarinic receptor
- Competitive antagonists of Ach at the muscarinic receptor (correct)
Urinary retention is a systemic side effect of Anticholinergics bronchodilators.
Urinary retention is a systemic side effect of Anticholinergics bronchodilators.
True (A)
What is the duration of action of Tiotropium Bromide?
What is the duration of action of Tiotropium Bromide?
24 hours
Ipratropium is a _____________ acting Anticholinergics bronchodilator.
Ipratropium is a _____________ acting Anticholinergics bronchodilator.
Match the following Anticholinergics bronchodilators with their duration of action:
Match the following Anticholinergics bronchodilators with their duration of action:
What is a contraindication for the use of Anticholinergics bronchodilators?
What is a contraindication for the use of Anticholinergics bronchodilators?
What are the classical antiasthma drugs?
What are the classical antiasthma drugs?
Inhaled corticosteroids are used to reduce bronchial smooth muscle constriction.
Inhaled corticosteroids are used to reduce bronchial smooth muscle constriction.
What is the primary goal of asthma management?
What is the primary goal of asthma management?
Inhalational devices are used to deliver antiasthma drugs directly to the __________.
Inhalational devices are used to deliver antiasthma drugs directly to the __________.
Match the following antiasthma drugs with their mechanism of action:
Match the following antiasthma drugs with their mechanism of action:
What is an essential supplemental measure during Glucocorticoids (GC) therapy?
What is an essential supplemental measure during Glucocorticoids (GC) therapy?
Inhaler technique mistakes are relatively rare among asthma patients.
Inhaler technique mistakes are relatively rare among asthma patients.
What is the purpose of Alendronate biphosphonate in GC therapy?
What is the purpose of Alendronate biphosphonate in GC therapy?
Patients treated with corticosteroids should be on a ______ diet.
Patients treated with corticosteroids should be on a ______ diet.
Match the following inhalational drug delivery systems with their descriptions:
Match the following inhalational drug delivery systems with their descriptions:
What is a common issue with asthma prescriptions?
What is a common issue with asthma prescriptions?
Spacer use is not recommended for children with pressurized metered-dose inhalers.
Spacer use is not recommended for children with pressurized metered-dose inhalers.
About ______% of patients may not adhere to their prescribed asthma treatment.
About ______% of patients may not adhere to their prescribed asthma treatment.
Study Notes
Corticosteroids/Glucocorticoids
- Patients treated with corticosteroids should be on a high protein diet
- Supplemental measures during GC therapy include:
- Diet rich in potassium and low in sodium
- Caloric management to prevent obesity
- High protein intake
- Appropriate antacid therapy
- Calcium and Vit D
- Alendronate biphosphonate to inhibit osteoclast activity
Inhalational Drug Delivery Systems
- Pressurized metered-dose inhalers are used for asthma treatment
- In children, pressurized metered-dose inhalers are best used with a spacer
- Nebulizers are also used for asthma treatment
Pharmaceutical Care Issues
- Inadequate prescription: about 40% of asthma patients may not have adequate prescription of asthma medications according to guidelines
- Low adherence: about 80% of patients may not adhere to their prescribed treatment
- Inhaler technique mistakes: approximately 17% of patients made critical mistakes with their inhaler technique
Classification of Asthma
- Asthma can be classified based on the severity of symptoms
Antiasthma Drugs
- Classical antiasthma drugs are:
- Bronchodilators
- Anti-inflammatory corticosteroids
Bronchodilators
- β2 receptor agonists are a type of bronchodilator
- Anticholinergics are a type of bronchodilator
- Examples: Ipratropium, Oxitropium, Tiotropium Bromide
- Mechanism: competitive antagonists of Ach at the muscarinic receptor
- Side effects: local (dry mouth, pharyngeal irritation), systemic (urinary retention, loss of accommodation, tachycardia, agitation, increased intraocular pressure)
- Contraindications: known hypersensitivity, narrow-angle glaucoma, gastrointestinal tract obstructions, urinary retention
Other Bronchodilators
- Magnesium Sulphate is a bronchodilator
Studying That Suits You
Use AI to generate personalized quizzes and flashcards to suit your learning preferences.
Description
This quiz covers the supplemental measures to be taken while on corticosteroid therapy, including dietary recommendations and medications to prevent various complications.
