44 Questions
Which family does the coronavirus belong to?
Coronaviridae
What is the genome type of coronavirus?
+SSRNA
What is the function of NSP14 in coronavirus?
RNA proofreading
What are the main clinical manifestations in severe COVID-19?
Congestion or runny nose, new loss of taste or smell
What are the types of vaccines approved against COVID-19?
mRNA, adenoviral vector, and nanoparticles
What is the incubation period of COVID-19?
2-5 days
How is SARS-CoV-2 transmitted?
By inhalation of infected respiratory droplets
What is the primary target cell for SARS-CoV-2?
Ciliated bronchial epithelial cells
What is the morphology of SARS-CoV-2?
Enveloped, 80-160nm in size, containing E1 and E2 glycoproteins
What is the pathogenesis of SARS-CoV-2?
Can cause multi-organ dysfunction syndrome
What is the mechanism of action of molnupiravir?
Causes mutations of RdRp
Which coronavirus has the largest genome of all RNA viruses?
SARS-CoV-2
What is the name of the protein that is involved in RNA synthesis in coronaviruses?
RdRp
How many human coronaviruses are known to date?
Seven
Which cells are primarily targeted by SARS-CoV-2?
Ciliated bronchial epithelial cells and type II pneumocytes
What is the function of the E2 glycoprotein in SARS-CoV-2?
Mediates viral attachment and membrane fusion
What is the main clinical manifestation in severe COVID-19?
Multi-organ dysfunction syndrome (MODS)
What is the effect of increased cytokine levels in severe COVID-19?
Induces a cytokine storm
What are the main types of COVID-19 vaccines approved?
mRNA, vector, inactivated, and nanoparticles
What is the most common extrapulmonary manifestation of COVID-19?
Dermatologic
What is the impact of COVID-19 at the pulmonary level?
Fluid collection within the bronchioles, alveolar instability, and the sloughing of endothelial cells
What is the incubation period of COVID-19?
2-5 days
Which of the following is NOT a common human coronavirus?
MERS-CoV
What is the function of NSP14 in coronaviruses?
RNA proofreading
What is the replication cycle of coronaviruses?
+SSRNA
What is the primary mode of transmission of SARS-CoV-2?
Inhalation of infected respiratory droplets
Which type of vaccine against COVID-19 is based on nanoparticles coated with spike protein?
Nanoparticles
What is the most common extrapulmonary manifestation of COVID-19?
Gastrointestinal
What is the impact of SARS-CoV-2 at the pulmonary level?
Alveolar instability and sloughing of endothelial cells
What is the primary target cell for SARS-CoV-2?
Ciliated bronchial epithelial cells and type II pneumocytes
What is the main pathophysiological mechanism of severe COVID-19?
All of the above
Which antiviral causes mutations of RdRp?
Molnupiravir
What is the morphology of SARS-CoV-2?
Envelope, 80-160nm in size, spike glycoproteins
Which coronavirus family does SARS-CoV-2 belong to?
Coronaviridae
What is the function of NSP14 in coronaviruses?
RNA proofreading
How many human coronaviruses are there with high pathogenic potential?
5
What are the main clinical manifestations of severe COVID-19?
Chest pain and shortness of breath
What are the types of vaccines approved against COVID-19?
mRNA and vector
What is the primary mode of transmission of SARS-CoV-2?
Airborne transmission
What is the impact of COVID-19 at the pulmonary level?
Fluid collection within the bronchioles
What is the primary receptor that SARS-CoV-2 targets?
ACE-2
What is the role of the E2 glycoprotein in SARS-CoV-2?
Mediates viral attachment and membrane fusion
What is the pathogenesis of SARS-CoV-2?
Can infect liver, kidneys, heart, and eyes
What is the effect of increased cytokine levels in severe COVID-19?
Increased cytokine storm
Test your knowledge on coronavirus classification with this quiz! Learn about the different orders, families, sub-families, and genus of coronaviruses, including the seven human coronaviruses known to date. Identify the common human coronaviruses and their respective classifications.
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