Corneal Physiology and Clinical Applications Quiz
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Corneal Physiology and Clinical Applications Quiz

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@mxrieen

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Questions and Answers

Which layer of the cornea is highly hydrophilic?

  • Endothelium
  • Epithelium
  • Basal lamina
  • Stroma (correct)

    • What is the primary contributor of glucose to all corneal layers?

  • Tears
  • Aqueous humor (correct)
  • Limbal capillaries
  • Vitamins

    • Which process is the principal provider of energy to epithelial cells?

  • Glycolysis (correct)
  • Glycogen synthesis
  • Krebs cycle
  • Lactic acid pathway

    • Where does lactic acid pass through in corneal stress?

    <p>Endothelium</p> Signup and view all the answers

    What can lactic acid accumulation in corneal stress lead to?

    <p>Acidosis and edema</p> Signup and view all the answers

    What happens to oxygen levels during sleep?

    <p>Decrease</p> Signup and view all the answers

    Which junctions restrict the amount of fluid entering from the tear film into the cornea?

    <p>Tight junctions</p> Signup and view all the answers

    How are the basal cells of the cornea connected to each other?

    <p>By gap junctions</p> Signup and view all the answers

    Which layer of the cornea obtains glucose from the aqueous humor by diffusion?

    <p>Endothelium</p> Signup and view all the answers

    What is essential for corneal transparency?

    <p>Corneal hydration</p> Signup and view all the answers

    What is the first response of epithelium after injury?

    <p>Stop basal cell mitosis</p> Signup and view all the answers

    Which layer of the cornea can regenerate if damaged?

    <p>Stroma</p> Signup and view all the answers

    What can contribute to astigmatism besides the cornea?

    <p>Lens</p> Signup and view all the answers

    What is the cause of recurrent corneal erosion?

    <p>Incomplete healing of an abrasion</p> Signup and view all the answers

    What is the characteristic feature of keratoconus?

    <p>Thinning and degeneration of the stroma</p> Signup and view all the answers

    What are Hassall-Henle bodies?

    <p>Small excrescences of the posterior surface of Descemet’s membrane</p> Signup and view all the answers

    What is indicative of endothelial dysfunction in the cornea?

    <p>Corneal guttata</p> Signup and view all the answers

    What can cause corneal edema resulting in impaired visual acuity?

    <p>Endothelial damage</p> Signup and view all the answers

    What can lead to corneal neovascularization?

    <p>Corneal infections</p> Signup and view all the answers

    What are characteristic symptoms of Herpes Simplex Virus (HSV) infection in the eye?

    <p>Red eye, photophobia, tearing</p> Signup and view all the answers

    What is the primary function of the Na/K pump in the corneal epithelium?

    <p>Moving K+ into the epithelium and Na+ into the stroma</p> Signup and view all the answers

    What drives the movement of water between the endothelium and anterior chamber?

    <p>Concentration gradient of ions</p> Signup and view all the answers

    How does the K+ channel respond to corneal changes in pH?

    <p>By moving more K+ into the aqueous, moving Cl- and water out to restore normal thickness</p> Signup and view all the answers

    What is the function of the Na+/2HCO3- cotransporter in the endothelium?

    <p>Moving water between endothelium and anterior chamber</p> Signup and view all the answers

    What is the primary source of oxygen for the cornea when the eye is open?

    <p>Atmosphere</p> Signup and view all the answers

    What happens to the partial pressure of O2 in the tears when the eye is closed?

    <p>Decreases to 55 mmHg</p> Signup and view all the answers

    Where do the posterior stroma and endothelium receive oxygen from when the eye is closed?

    <p>Aqueous humor</p> Signup and view all the answers

    What is the primary source of oxygen for the epithelium when the eye is closed?

    <p>Superior palpebral conjunctiva and limbal vasculature</p> Signup and view all the answers

    What drives the regeneration of corneal epithelium when the basement membrane (BM) remains intact?

    <p>Mitosis of basal cells</p> Signup and view all the answers

    What is the function of the Na+/K+/Cl- cotransporter in the corneal epithelium?

    <p>Moving K+ and Cl- into the epithelium</p> Signup and view all the answers

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