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Questions and Answers
Which muscle is responsible for the primary lateral depressor of the eyebrow?
Which muscle is responsible for the primary lateral depressor of the eyebrow?
At what stage of development do the eyelids form from the folds of surface ectoderm filled with mesenchyme?
At what stage of development do the eyelids form from the folds of surface ectoderm filled with mesenchyme?
Which cranial nerve innervates the muscles responsible for eyebrow movements?
Which cranial nerve innervates the muscles responsible for eyebrow movements?
What is the main function of the eyelids?
What is the main function of the eyelids?
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What is the most common type of blinking?
What is the most common type of blinking?
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What sensory stimuli can elicit a blink reflex?
What sensory stimuli can elicit a blink reflex?
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What is the role of Bell's Phenomenon during a blink?
What is the role of Bell's Phenomenon during a blink?
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What is the role of the eyelids in tear production?
What is the role of the eyelids in tear production?
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What is the function of the muscle of Horner in tear drainage?
What is the function of the muscle of Horner in tear drainage?
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What is the function of eyelashes?
What is the function of eyelashes?
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What is the condition characterized by the inability to oppose the eyelids on attempted lid closure?
What is the condition characterized by the inability to oppose the eyelids on attempted lid closure?
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What is the common cause of yellow plaques of lipid near the inner canthus?
What is the common cause of yellow plaques of lipid near the inner canthus?
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What is the condition characterized by the loss of eyelashes?
What is the condition characterized by the loss of eyelashes?
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What is the condition characterized by the eversion of the eyelid margin?
What is the condition characterized by the eversion of the eyelid margin?
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What is the vertical fold of skin at the nasal canthus that gradually disappears as the bridge of the nose develops?
What is the vertical fold of skin at the nasal canthus that gradually disappears as the bridge of the nose develops?
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What is the condition characterized by the upper eyelid drooping or sagging?
What is the condition characterized by the upper eyelid drooping or sagging?
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What is the function of the lacrimal punctum?
What is the function of the lacrimal punctum?
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Where is the superior palpebral crease located?
Where is the superior palpebral crease located?
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What separates the tarsal and orbital portion of the upper eyelid?
What separates the tarsal and orbital portion of the upper eyelid?
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What is the function of the malar crease?
What is the function of the malar crease?
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Where is the caruncle located?
Where is the caruncle located?
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What is the function of the plica semilunaris?
What is the function of the plica semilunaris?
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Where are the lacrimal puncta located?
Where are the lacrimal puncta located?
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What is the function of the lacrimal lake?
What is the function of the lacrimal lake?
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Where are the meibomian glands located?
Where are the meibomian glands located?
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What is the function of the tarsal plate?
What is the function of the tarsal plate?
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What divides the eyelid margin into lacrimal and ciliary portions?
What divides the eyelid margin into lacrimal and ciliary portions?
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Which layer of the eyelids contains the palpebral portion of the orbicularis oculi?
Which layer of the eyelids contains the palpebral portion of the orbicularis oculi?
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What is the function of the orbital septum in the eyelids?
What is the function of the orbital septum in the eyelids?
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Which muscle is a specialized area within the palpebral portion of the eyelids used for spontaneous and reflex blinking?
Which muscle is a specialized area within the palpebral portion of the eyelids used for spontaneous and reflex blinking?
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Which glands are large sebaceous glands located posterior to the eyelashes and produce the lipid layer of the tear film?
Which glands are large sebaceous glands located posterior to the eyelashes and produce the lipid layer of the tear film?
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What provides sensory innervation to the eyelids?
What provides sensory innervation to the eyelids?
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Which muscles are part of the posterior muscular system of the eyelids?
Which muscles are part of the posterior muscular system of the eyelids?
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What are the Glands of Zeis associated with?
What are the Glands of Zeis associated with?
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Where is the palpebral conjunctiva located?
Where is the palpebral conjunctiva located?
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What are the Glands of Moll associated with?
What are the Glands of Moll associated with?
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Which nerve provides voluntary motor innervation to the eyelids?
Which nerve provides voluntary motor innervation to the eyelids?
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What is the composition of the tarsal plate in the eyelids?
What is the composition of the tarsal plate in the eyelids?
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What is the function of the Meibomian glands in the eyelids?
What is the function of the Meibomian glands in the eyelids?
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What provides involuntary motor innervation to the eyelids?
What provides involuntary motor innervation to the eyelids?
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Which structure ensures the smooth movement of the eyelids over the globe?
Which structure ensures the smooth movement of the eyelids over the globe?
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What is the main function of the caruncle?
What is the main function of the caruncle?
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Which condition is characterized by an opaque, slightly elevated mass of modified conjunctival tissue in the interpalpebral area?
Which condition is characterized by an opaque, slightly elevated mass of modified conjunctival tissue in the interpalpebral area?
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What is the composition of follicles in the conjunctiva?
What is the composition of follicles in the conjunctiva?
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Where are papillae generally located?
Where are papillae generally located?
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What is the function of the plica semilunaris?
What is the function of the plica semilunaris?
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What is the main cause of yellow plaques of lipid near the inner canthus?
What is the main cause of yellow plaques of lipid near the inner canthus?
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What is the condition characterized by fibrovascular overgrowth of bulbar conjunctiva into the cornea?
What is the condition characterized by fibrovascular overgrowth of bulbar conjunctiva into the cornea?
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What supplies blood to the palpebral and fornix portions of the conjunctiva?
What supplies blood to the palpebral and fornix portions of the conjunctiva?
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Which structure contains smooth muscle, goblet cells, and adipose tissue?
Which structure contains smooth muscle, goblet cells, and adipose tissue?
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What is the main cause of follicles and papillae in the conjunctiva?
What is the main cause of follicles and papillae in the conjunctiva?
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What is the main function of the bulbar conjunctiva?
What is the main function of the bulbar conjunctiva?
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What is the main function of the lipid layer in the tear film?
What is the main function of the lipid layer in the tear film?
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Which layer of the tear film contains antibacterial substances such as lysozyme and lactoferrin?
Which layer of the tear film contains antibacterial substances such as lysozyme and lactoferrin?
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What is the primary source of atmospheric oxygen for the cornea?
What is the primary source of atmospheric oxygen for the cornea?
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Which component of the tear film contains peptide growth factors and cytokines that can regulate ocular surface wound and repair?
Which component of the tear film contains peptide growth factors and cytokines that can regulate ocular surface wound and repair?
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What is the normal Tear Break Up Time (TBUT)?
What is the normal Tear Break Up Time (TBUT)?
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What is the main cause of Congenital Dacryostenosis?
What is the main cause of Congenital Dacryostenosis?
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What is the most common congenital lacrimal abnormality?
What is the most common congenital lacrimal abnormality?
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What is the characteristic symptom of Canaliculitis?
What is the characteristic symptom of Canaliculitis?
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What is Dacryocystitis usually caused by?
What is Dacryocystitis usually caused by?
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What is the recommended treatment for Acute Canaliculitis with a pouting puncta?
What is the recommended treatment for Acute Canaliculitis with a pouting puncta?
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What is the main cause of Dacryoadenitis?
What is the main cause of Dacryoadenitis?
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What is the characteristic symptom of Dacryocystorhinostomy (DCR)?
What is the characteristic symptom of Dacryocystorhinostomy (DCR)?
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What is the total volume of tears on the ocular surface?
What is the total volume of tears on the ocular surface?
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What is the normal tear production rate per minute?
What is the normal tear production rate per minute?
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What is the average tear film pH?
What is the average tear film pH?
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What is the function of the lacrimal gland's orbital portion?
What is the function of the lacrimal gland's orbital portion?
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What is the composition of the lacrimal gland's reflex secretion?
What is the composition of the lacrimal gland's reflex secretion?
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Which nerve pathway is involved in reflex tearing?
Which nerve pathway is involved in reflex tearing?
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What is the role of the lacrimal gland fluid?
What is the role of the lacrimal gland fluid?
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What artery supplies the lacrimal gland?
What artery supplies the lacrimal gland?
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What is the primary innervation of the lacrimal gland?
What is the primary innervation of the lacrimal gland?
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What is the role of the mucous layer in the tear film?
What is the role of the mucous layer in the tear film?
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What is the composition of the normal tear film?
What is the composition of the normal tear film?
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What is the role of the eyelids in tear distribution?
What is the role of the eyelids in tear distribution?
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Where are the lacrimal puncta located?
Where are the lacrimal puncta located?
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What is the function of the valve of Hasner in the nasolacrimal duct?
What is the function of the valve of Hasner in the nasolacrimal duct?
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What is the main function of the common canaliculus (ampulla of Maier) in the nasolacrimal drainage system?
What is the main function of the common canaliculus (ampulla of Maier) in the nasolacrimal drainage system?
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What is the role of the lacrimal sac in tear drainage?
What is the role of the lacrimal sac in tear drainage?
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What is the function of the orbital septum in relation to the lacrimal sac?
What is the function of the orbital septum in relation to the lacrimal sac?
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What is the function of the valve of Rosenmuller in the nasolacrimal drainage system?
What is the function of the valve of Rosenmuller in the nasolacrimal drainage system?
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What is the role of the Horner’s muscle fibers in the nasolacrimal drainage system?
What is the role of the Horner’s muscle fibers in the nasolacrimal drainage system?
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What is the main function of the membranous folds within the sac and nasolacrimal duct?
What is the main function of the membranous folds within the sac and nasolacrimal duct?
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What is the function of the lacrimal punctum in the nasolacrimal drainage system?
What is the function of the lacrimal punctum in the nasolacrimal drainage system?
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What is the role of the lateral displacement of the lateral wall during tear drainage?
What is the role of the lateral displacement of the lateral wall during tear drainage?
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What is the primary function of the corneal endothelium?
What is the primary function of the corneal endothelium?
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Which layer of the cornea contains cells that do not replicate and wear out with age?
Which layer of the cornea contains cells that do not replicate and wear out with age?
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What is the normal range of corneal endothelial cell density in adults?
What is the normal range of corneal endothelial cell density in adults?
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What is the total refractive power of the eye, and how much of it is attributable to the cornea?
What is the total refractive power of the eye, and how much of it is attributable to the cornea?
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What is the primary source of atmospheric oxygen for the cornea?
What is the primary source of atmospheric oxygen for the cornea?
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Which nerve provides voluntary motor innervation to the eyelids?
Which nerve provides voluntary motor innervation to the eyelids?
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Where are the corneal nerves located?
Where are the corneal nerves located?
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What is the function of the lacrimal gland's orbital portion?
What is the function of the lacrimal gland's orbital portion?
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What is the composition of the normal tear film?
What is the composition of the normal tear film?
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What provides sensory innervation to the eyelids?
What provides sensory innervation to the eyelids?
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What is the main cause of Dacryocystitis?
What is the main cause of Dacryocystitis?
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What is the main function of the membranous folds within the sac and nasolacrimal duct?
What is the main function of the membranous folds within the sac and nasolacrimal duct?
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What is the approximate thickness of the corneal epithelium?
What is the approximate thickness of the corneal epithelium?
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Which layer of the cornea is composed of collagen fibrils and is prenatally produced?
Which layer of the cornea is composed of collagen fibrils and is prenatally produced?
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What is the primary function of the corneal Bowman’s layer?
What is the primary function of the corneal Bowman’s layer?
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What is the approximate thickness of the corneal stroma?
What is the approximate thickness of the corneal stroma?
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What contributes to the transparency of the corneal stroma?
What contributes to the transparency of the corneal stroma?
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Which part of the cornea thickens throughout life and consists of two laminae?
Which part of the cornea thickens throughout life and consists of two laminae?
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Where are the stem cells for corneal basal cell layer renewal located?
Where are the stem cells for corneal basal cell layer renewal located?
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What is the primary composition of the corneal stroma?
What is the primary composition of the corneal stroma?
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What is the primary function of the corneal endothelium?
What is the primary function of the corneal endothelium?
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Through which layer do the corneal nerves pass?
Through which layer do the corneal nerves pass?
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Where are the corneal stem cells located?
Where are the corneal stem cells located?
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What is the primary role of the corneal Descemet’s membrane?
What is the primary role of the corneal Descemet’s membrane?
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What is the radius of curvature of the central cornea?
What is the radius of curvature of the central cornea?
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Which layer of the cornea is produced by the corneal endothelium?
Which layer of the cornea is produced by the corneal endothelium?
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What is the refractive power of the cornea?
What is the refractive power of the cornea?
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What is the central cornea thickness?
What is the central cornea thickness?
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What is the radius of curvature of the central cornea?
What is the radius of curvature of the central cornea?
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Which layer of the cornea contributes to the formation of Bowman’s layer?
Which layer of the cornea contributes to the formation of Bowman’s layer?
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Study Notes
Anatomy and Physiology of the Eyelids
- Palpebral portion of the eyelids is used for spontaneous and reflex blinking
- Muscle of Riolan and Muscle of Horner are two specialized areas within the palpebral portion
- The orbital septum is a dense irregular connective tissue layer that serves as a barrier and restricts fat from falling onto the lid margins
- The posterior muscular system includes the superior levator palpebrae muscle and the superior and inferior tarsal muscle of Muller
- The tarsal plate is made of dense irregular connective tissue and contains palpebral ligaments that hold the tarsal plates in position
- The palpebral conjunctiva is the inner lining of the eyelids, consisting of a stratified squamous epithelial layer and a submucosa
- Meibomian glands are large sebaceous glands located posterior to the eyelashes and produce the lipid layer of the tear film
- Glands of Zeis are modified sebaceous glands associated with eyelash follicles
- Glands of Moll are modified sweat glands associated with eyelash follicles
- The trigeminal nerve provides sensory innervation to the eyelids
- Voluntary motor innervation is provided by the temporal and zygomatic branches of the facial nerve
- Involuntary motor innervation is provided by the sympathetic nervous system
Tear Film and Lacrimal Gland Anatomy
- Mucous layer, composed of glycocalyx and mucin, makes up 30-40% of the total tear film and aids in adhesion and microbe entrapment.
- Eyelids spread the mucous layer evenly over the corneal epithelium, accepting the mucous and creating a hydrophilic surface to accept tears.
- Total volume of tears on the ocular surface is 7 to 10 μl, with normal tear production at about 1 μl/min and the eye's capacity at 20-30 μl.
- Normal tear film is isotonic and its osmolarity varies with factors such as blink rate, humidity, ocular pathology, and contact lens use.
- Average tear film pH is 7.45, with good buffering ability, allowing tolerance of ophthalmic solutions with different pH levels.
- The lacrimal system has a dual function: secretory component contributing to tear formation and excretory component providing drainage from the eye into the nose.
- The lacrimal gland includes the main and accessory glands, meibomian glands, and conjunctival goblet cells.
- The lacrimal gland has orbital and palpebral lobes, with the orbital portion being larger and almond-shaped.
- The gland consists of lobules made of acini, which secrete water, electrolytes, and antibacterial agents, with reflex secretion increasing in response to stimuli.
- The lacrimal gland is supplied by the lacrimal artery and innervated by sensory, vasomotor sympathetic, and secretomotor parasympathetic nerves.
- Reflex tearing occurs in response to external stimuli, with the afferent pathway through the trigeminal nerve and the parasympathetic pathway through the facial nerve.
- Lacrimal gland fluid is secreted into the lateral part of the upper fornix, descends across the anterior surface of the globe, and is spread across the ocular surface by blinking.
Corneal Histological Features
- The cornea is approximately 71mm in size and serves as the principal refracting component of the eye.
- It is transparent and avascular, providing optimal light transmittance, with the anterior surface covered by a tear film.
- The corneal layers, from anterior to posterior, consist of the epithelium, Bowman’s layer, stroma, Descemet’s membrane, and endothelium.
- The corneal epithelium is stratified squamous nonkeratinized epithelium, measuring approximately 50 μm and thickening at the periphery.
- It has three different layers: surface layer, wing cells, and basal layer, each with specific characteristics and functions.
- Cell proliferation occurs in the basal layer, with stem cells located in a band around the corneal periphery, serving as the source for renewal of the corneal basal cell layer.
- The corneal Bowman’s layer is an acellular dense layer composed of random collagen fibrils, approximately 8-14 μm thick, and is prenatally produced, so it cannot regenerate.
- The corneal stroma, also known as Substantia Propria, is approximately 500 μm thick and composed of collagen fibers, keratocytes, and extracellular ground substance.
- Collagen fibers in the stroma are 25-35 μm in diameter, form 200-300 parallel layers called lamellae, and contribute to stromal transparency.
- Corneal Descemet’s membrane is the true basement membrane of the endothelium, thickening throughout life, and consists of two laminae.
- The very regular arrangement of the stromal component and the small diameter of the fibrils contribute to stromal transparency.
- The corneal nerves pass through Bowman’s layer, losing their Schwann cell covering.
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Test your knowledge of the anatomy and physiology of the eyelids with this quiz. Explore topics such as the structure of the eyelids, specialized muscles, connective tissues, glandular structures, and innervation. Perfect for students, medical professionals, or anyone interested in understanding the intricacies of the eyelids.