COPD Quiz

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Questions and Answers

Which of the following is the main cause of Chronic Obstructive Pulmonary Disease (COPD)?

  • Lung infections
  • Smoking cigarettes (correct)
  • Exposure to air pollution
  • Genetic factors

What is the effect of oxidative stress on α1-antitrypsin in COPD?

  • It increases its ability to inhibit neutrophil elastase
  • It reduces its ability to inhibit neutrophil elastase (correct)
  • It causes oxidation of neutrophil elastase
  • It has no effect on its ability to inhibit neutrophil elastase

What are the sources of oxidants in COPD?

  • Smoking cigarettes and air pollution (correct)
  • Smoking cigarettes only
  • Exposure to air pollution only
  • Genetic factors only

What is the relationship between oxidative stress and lung function in COPD patients?

<p>Oxidative stress is inversely correlated with lung function (D)</p> Signup and view all the answers

What is the effect of chronic exposure to oxidants in cigarette smoke on COPD pathogenesis?

<p>It promotes cell death and fibrosis (B)</p> Signup and view all the answers

What is consistently detected in the exhaled breath condensate of patients with COPD?

<p>Increased levels of oxidants (B)</p> Signup and view all the answers

Which of the following is significantly elevated in patients with COPD compared to controls?

<p>Levels of (8-OHdG) (C)</p> Signup and view all the answers

Where does oxidative stress occur in patients with COPD?

<p>Both in the lung and systemically (D)</p> Signup and view all the answers

What is the effect of oxidative stress on HNE levels in patients with COPD?

<p>It increases HNE levels (B)</p> Signup and view all the answers

What is the effect of oxidative stress on (8-OHdG) levels in patients with COPD?

<p>It increases (8-OHdG) levels (D)</p> Signup and view all the answers

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