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Questions and Answers
What are the two most common diseases classified under COPD?
What are the two most common diseases classified under COPD?
What is the first treatment approach for mild to moderate exacerbations of COPD?
What is the first treatment approach for mild to moderate exacerbations of COPD?
What phenomenon allows patients with COPD to breathe effectively despite lower oxygen levels?
What phenomenon allows patients with COPD to breathe effectively despite lower oxygen levels?
What is considered an adequate SaO2 level for monitoring COPD patients?
What is considered an adequate SaO2 level for monitoring COPD patients?
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Which treatments are typically used for managing COPD exacerbations?
Which treatments are typically used for managing COPD exacerbations?
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What is the primary focus of prehospital care for most patients with respiratory distress?
What is the primary focus of prehospital care for most patients with respiratory distress?
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Which population is affected by acute respiratory distress?
Which population is affected by acute respiratory distress?
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What should EMS providers anticipate regarding oxygen use in prehospital care?
What should EMS providers anticipate regarding oxygen use in prehospital care?
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What condition is specifically mentioned that complicates the use of oxygen?
What condition is specifically mentioned that complicates the use of oxygen?
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How is oxygen typically administered to patients with COPD at home?
How is oxygen typically administered to patients with COPD at home?
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In patients suffering from asthma, the underlying issue primarily involves:
In patients suffering from asthma, the underlying issue primarily involves:
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What is a common side effect of long-term use of nasal cannulas for oxygen therapy?
What is a common side effect of long-term use of nasal cannulas for oxygen therapy?
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What type of device may be required for patients needing long-term oxygen therapy?
What type of device may be required for patients needing long-term oxygen therapy?
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What condition do patients report when experiencing bronchospasm?
What condition do patients report when experiencing bronchospasm?
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Which of the following best describes the effect of mucosal edema on the airways?
Which of the following best describes the effect of mucosal edema on the airways?
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Which type of bronchodilator selectively acts on bronchial smooth muscle?
Which type of bronchodilator selectively acts on bronchial smooth muscle?
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What precaution should be taken when administering beta2 agonists to patients with heart disease?
What precaution should be taken when administering beta2 agonists to patients with heart disease?
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Which of the following is an effect of stimulating alpha adrenergic receptors?
Which of the following is an effect of stimulating alpha adrenergic receptors?
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What is a potential side effect of excessive doses of beta2 agonists?
What is a potential side effect of excessive doses of beta2 agonists?
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Which of the following medications is an example of a nonselective bronchodilator?
Which of the following medications is an example of a nonselective bronchodilator?
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What triggers acute asthma attacks?
What triggers acute asthma attacks?
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What are intrinsic triggers of asthma?
What are intrinsic triggers of asthma?
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What is the primary goal in managing asthma?
What is the primary goal in managing asthma?
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What is the first-line medication for treating asthma exacerbations?
What is the first-line medication for treating asthma exacerbations?
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Which medication is considered the most common inhaled drug for reversible bronchospasm?
Which medication is considered the most common inhaled drug for reversible bronchospasm?
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What is a significant advantage of second-generation beta2 agonists over first-generation?
What is a significant advantage of second-generation beta2 agonists over first-generation?
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Which benefit is associated with third-generation beta2 agonists?
Which benefit is associated with third-generation beta2 agonists?
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How do parenteral medications fit into asthma management?
How do parenteral medications fit into asthma management?
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What is a commonly believed advantage of Levalbuterol compared to Albuterol?
What is a commonly believed advantage of Levalbuterol compared to Albuterol?
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What is the primary role of ipratropium bromide in asthma management?
What is the primary role of ipratropium bromide in asthma management?
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How does the mechanism of action for albuterol differ from that of ipratropium bromide?
How does the mechanism of action for albuterol differ from that of ipratropium bromide?
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What combination product utilizes both albuterol and ipratropium bromide?
What combination product utilizes both albuterol and ipratropium bromide?
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Which treatment is considered for patients with a prolonged transport time during an acute exacerbation?
Which treatment is considered for patients with a prolonged transport time during an acute exacerbation?
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Which corticosteroids are commonly used in managing moderate or severe asthma symptoms?
Which corticosteroids are commonly used in managing moderate or severe asthma symptoms?
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What should be done when the initial Peak Expiratory Flow Rate (PEFR) is less than 50% of predicted values?
What should be done when the initial Peak Expiratory Flow Rate (PEFR) is less than 50% of predicted values?
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In what scenario is ipratropium bromide less likely to be used as a primary treatment?
In what scenario is ipratropium bromide less likely to be used as a primary treatment?
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What characteristic describes the clinical presentation of a patient with an asthma attack or COPD exacerbation?
What characteristic describes the clinical presentation of a patient with an asthma attack or COPD exacerbation?
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What is the recommended action when the PEFR does not improve by at least 10% after bronchodilator therapy?
What is the recommended action when the PEFR does not improve by at least 10% after bronchodilator therapy?
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Which statement about aminophylline and other methylxanthines is accurate?
Which statement about aminophylline and other methylxanthines is accurate?
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Which condition is magnesium sulfate particularly beneficial for in asthma patients?
Which condition is magnesium sulfate particularly beneficial for in asthma patients?
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What is a significant risk associated with the administration of epinephrine in asthma patients?
What is a significant risk associated with the administration of epinephrine in asthma patients?
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In what scenario is epinephrine still indicated for asthma management?
In what scenario is epinephrine still indicated for asthma management?
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Which of the following best describes the role of rebound bronchospasm in asthma management?
Which of the following best describes the role of rebound bronchospasm in asthma management?
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What should be taken into consideration when using epinephrine for adults with asthma?
What should be taken into consideration when using epinephrine for adults with asthma?
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Which statement about corticosteroids in asthma treatment is true?
Which statement about corticosteroids in asthma treatment is true?
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Study Notes
Drugs Used to Treat Respiratory Emergencies
- Respiratory distress is a common presentation in prehospital settings, affecting people of all ages and demographics.
- While underlying causes of respiratory distress vary, reversible bronchial constriction (bronchospasm) is a frequent target of prehospital treatment.
- Advanced life support (ALS) interventions, including respiratory medications, considerably reduce mortality in respiratory distress cases.
Oxygen
- Oxygen is the most frequently used medication in prehospital settings.
- Oxygen use has associated risks and benefits.
- Daily oxygen use by prehospital providers often lacks consideration of its pharmacological properties.
- Current guidelines suggest titrating oxygen to prescribed saturation levels rather than applying it indiscriminately, particularly in neonatal resuscitation, COPD exacerbations, and acute coronary syndromes.
- Continuous oxygen needs may require a transtracheal catheter for some patients with COPD.
- Transtracheal catheters, like nasal cannulas, are used for long-term oxygen therapy in chronic lung diseases.
- Nasal cannulas might cause discomfort at night, so a transtracheal catheter would be used in those cases
Bronchodilators
- Asthma and COPD can lead to respiratory distress due to functional narrowing of the conducting airways.
- Symptoms can feel like breathing through a straw.
- Bronchospasm, narrowing of the bronchial smooth muscle, decreases airway diameter.
- Airway inflammation and edema also cause airway narrowing.
- Increased secretions within the airways compound respiratory distress in these conditions.
- Bronchodilators can be selective or nonselective, targeting different receptors.
- Selective agents generally focus on bronchial smooth muscle, effectively improving condition with minimal side effects.
- Selective beta2 agonists (like albuterol) relax bronchial smooth muscle without increasing heart rate or blood pressure.
- Beta2 agonists should be used cautiously for those with heart conditions and the electrocardiogram should be monitored during and after treatment.
- Nonselective agents act on alpha, beta1, and beta2 adrenergic receptors. Alpha receptor stimulation increases blood pressure, beta1 acts on the heart increasing rate and contractility, and beta2 relaxes bronchial smooth muscle, allowing for bronchodilation.
- Racemic epinephrine is an example of a nonselective bronchodilator.
Management of Asthma
- Avoiding triggers, whenever possible, is a key management strategy for asthma.
- In prehospital settings, initial interventions focus on reversing acute bronchospasm.
- Inhaled beta2-specific drugs are the first-line treatment for asthma.
- Intravenous medications are used if inhaled bronchodilators are ineffective.
- Albuterol (Proventil, Ventolin) is a common inhaled bronchodilator targeting beta2 receptors.
- Levalbuterol (Xopenex) is a newer form of albuterol with supposedly fewer adverse effects.
- Ipratropium bromide (Atrovent) is an anticholinergic that targets bronchospasm in severe cases or if beta2 agonists are ineffective.
- Combination products like Albuterol/ipratropium (Combivent) deliver both medications in a single preparation.
Second-Line Therapy for Acute Asthma Exacerbation
- Lung conditions causing obstruction, like COPD, present a clinical picture of gasping for breath and use of accessory muscles of respiration.
- While bronchodilators treat symptoms, they don't address the underlying cause.
- Prolonged transport times suggest including corticosteroids (methylprednisolone, dexamethasone) to manage the inflammatory processes related to exacerbation.
- PEFR (peak expiratory flow rate) can guide therapeutic interventions and determine exacerbation severity/response to therapy.
- If PEFR is less than 50% of predicted, corticosteroids are administered after ipratropium.
- Corticosteroids should be considered when PEFR doesn't improve at least 10% post-bronchodilator therapy or is less than 70% after 1 hour.
- Aminophylline and other methylxanthines, once frequently used, are less commonly recommended for acute respiratory distress scenarios.
- Magnesium sulfate can help decrease bronchospasm in some patients who don't respond well to beta2 agonists.
- For young patients, epinephrine was once the preferred treatment, but its short-term and undesirable effects make it a less popular choice.
- Rebound bronchospasm can occur with epinephrine administration, so it should be used with caution
- Epinephrine is still considered if an anaphylactic reaction is suspected.
COPD Management
- In COPD exacerbations, treatment initially focuses on oxygenation and ventilation.
- Careful oxygen administration is key, as an overdose removes the hypoxic respiratory drive that helps patients breath.
- Consider a pulse oximetry level in the low 90s as adequate.
- Similar to asthma management, bronchodilators and corticosteroids can be used to manage COPD exacerbations.
Overview of Asthma
- Acute asthma attacks affect all ages, resulting from reactions in the body (intrinsic) or from outside factors (extrinsic).
- Asthma triggers range from exertion or stress (intrinsic) to animal dander, dust, pollen, and cleaning products (extrinsic).
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Description
Test your knowledge on Chronic Obstructive Pulmonary Disease (COPD) management strategies and treatments. This quiz covers common diseases under COPD, treatment approaches for exacerbations, and important monitoring levels for patients. See how well you understand the complexities of managing COPD!