Podcast
Questions and Answers
What is a common viral infection involved in exacerbations of COPD?
What is a common viral infection involved in exacerbations of COPD?
- Rhinovirus (correct)
- Influenza A virus
- Varicella-zoster virus
- Hepatitis B virus
Why can bacteria proliferate and persist in COPD airways?
Why can bacteria proliferate and persist in COPD airways?
- Defective innate immune responses (correct)
- Excessive oxygen levels
- Overactive alveolar macrophages
- Lack of nutrients in the airways
Which of the following is NOT an associated feature of systemic inflammation in COPD?
Which of the following is NOT an associated feature of systemic inflammation in COPD?
- Nutritional abnormalities
- Weight loss
- Improved lung function (correct)
- Skeletal muscle dysfunction
Why is persistent systemic inflammation considered a novel phenotype in COPD?
Why is persistent systemic inflammation considered a novel phenotype in COPD?
What percentage of patients with COPD show some components of systemic inflammation?
What percentage of patients with COPD show some components of systemic inflammation?
What can lead to bacterial exacerbation in COPD?
What can lead to bacterial exacerbation in COPD?
What are the common manifestations of chronic inflammation in chronic obstructive pulmonary disease (COPD)?
What are the common manifestations of chronic inflammation in chronic obstructive pulmonary disease (COPD)?
Which physiological change is associated with COPD?
Which physiological change is associated with COPD?
What effect does alveolar destruction have on gas exchange in COPD?
What effect does alveolar destruction have on gas exchange in COPD?
Which lung pathology is characterized by premature closure of airways on expiration?
Which lung pathology is characterized by premature closure of airways on expiration?
What contributes to the inefficient mixing of inspired air in COPD?
What contributes to the inefficient mixing of inspired air in COPD?
Which event is NOT a result of chronic inflammation in COPD?
Which event is NOT a result of chronic inflammation in COPD?
What is considered the hallmark of COPD?
What is considered the hallmark of COPD?
Which cell type is important in the pathogenesis of COPD due to their elevated levels in sputum and bronchoalveolar lavage fluid?
Which cell type is important in the pathogenesis of COPD due to their elevated levels in sputum and bronchoalveolar lavage fluid?
What is a characteristic feature of alveolar macrophages from COPD patients?
What is a characteristic feature of alveolar macrophages from COPD patients?
In what percentage of COPD patients is eosinophilic inflammation found?
In what percentage of COPD patients is eosinophilic inflammation found?
What is the role of eosinophils in COPD pathogenesis?
What is the role of eosinophils in COPD pathogenesis?
What percentage of patients with stable COPD experience bacterial infection?
What percentage of patients with stable COPD experience bacterial infection?
