Control of Activating Effect in Aromatic Amine Substitution
Learn how to control the activating effect of -NH2 group in aromatic amine substitution reactions by protecting it through acetylation with acetic anhydride. This method helps in directing the substitution to the desired position.
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Control of Activating Effect in Aromatic Amine Substitution
Quiz • 30 Questions
Study Notes
3 min • Summary
Control of Activating Effect in Aromatic Amine Substitution - Podcast
Podcast
Materials
List of Questions30 questions
- Question 1
- Formation of multiple isomers
- Their very high reactivity
- Substitution tends to occur at meta-positions
- Their low reactivity
- Question 2
- By protecting it with a bromine atom
- By reducing its reactivity
- By acetylating it with acetic anhydride
- By oxidizing it to nitro group
- Question 3
- Because aniline is a poor nucleophile
- Due to the activation of benzene ring
- Nitration at ortho and para positions only
- Presence of acidic medium
- Question 4
- Controls the nitration reaction to obtain p-nitro derivative
- Leads to formation of more ortho and para derivatives
- Increases the yield of meta derivatives
- Decreases the yield of all derivatives
- Question 5
- It deactivates the benzene ring
- It is meta directing and leads to meta derivative formation
- It forms tarry oxidation products
- It becomes ortho directing
- Question 6
- It increases the activating effect
- It decreases the activating effect
- Changes the position of substitution
- No effect on activating effect
- Question 7
- Hoffmann bromamide degradation reaction
- Ascent of amine series
- Reduction of amides with lithium aluminium hydride
- Gabriel phthalimide synthesis
- Question 8
- Potassium salt of phthalimide is not formed in the reaction
- Aromatic compounds do not react with ethanolic potassium hydroxide
- Aromatic amines are highly unstable compounds
- Aryl halides do not undergo nucleophilic substitution with the anion formed by phthalimide
- Question 9
- Hoffmann bromamide degradation reaction
- Gabriel phthalimide synthesis
- Reduction of amides with lithium aluminium hydride
- Ascent of amine series
- Question 10
- Aldehydes
- Amines
- Carboxylic acids
- Ketones
- Question 11
- To form more stable products
- To increase the carbon content of the amine
- To enhance the color of the product
- To decrease the carbon content of the amine
- Question 12
- Potassium hydroxide
- Lithium aluminium hydride
- Bromine
- Ethanol
- Question 13
- The number of hydrogen atoms attached to nitrogen atom
- The type of solvent used in the reaction
- The number of carbon atoms attached to nitrogen atom
- The presence of unshared electron pair on carbon atom
- Question 14
- Primary amines
- Quaternary amines
- Tertiary amines
- Secondary amines
- Question 15
- As nucleophiles
- As oxidizing agents
- As catalysts
- As acids
- Question 16
- Acid-base neutralization reaction
- Combustion reaction
- Reduction reaction
- Oxidation reaction
- Question 17
- Formation of salts with acids
- Solubility in water
- Solubility in organic solvents like ether
- Insolubility in water
- Question 18
- [H2O] = K/[R−NH2]
- [R−NH2]/[R−NH3] = K[H2O]
- [R−NH2] = K[H2O]
- [H2O] = Kb/[R−NH3]
- Question 19
- Aniline
- Aryl fluoride
- Nitrobenzene
- Phenol
- Question 20
- Phosphinic acid
- Ethylene glycol
- Hypochlorous acid
- Sulfuric acid
- Question 21
- 283 K
- 293 K
- 273 K
- 303 K
- Question 22
- Benzoic acid
- p-Hydroxyazobenzene
- Acetophenone
- Toluene
- Question 23
- Ortho position
- Para position
- Aliphatic position
- Meta position
- Question 24
- Extended conjugate system
- No aromatic rings involved
- No -N=N- bond present
- Reduced conjugate system
- Question 25
- Electron releasing groups
- Hydrogen bonding
- Electron withdrawing groups
- Steric hindrance
- Question 26
- Aromatic amines
- Primary amines
- Tertiary amines
- Secondary amines
- Question 27
- Ammonia
- p-Toluenesulphonyl chloride
- Aniline
- Acetyl chloride
- Question 28
- Carboxyl group
- Amino group
- Hydroxyl group
- Acetyl group
- Question 29
- By treating with ammonia
- By treating with hydrogen peroxide
- By treating with carboxylic acid
- By treating with acetyl chloride
- Question 30
- Aromatic amines
- Secondary amines
- Primary amines
- Tertiary amines