Podcast
Questions and Answers
What is one of the pathophysiologic explanations for allergic-like hypersensitivity reactions?
What is one of the pathophysiologic explanations for allergic-like hypersensitivity reactions?
- Conversion of nitric oxide into L-arginine
- Activation of the contact and complement systems (correct)
- Activation of the IV clotting system
- Conversion of L-arginine into oxygen
What is a benefit of premedication according to the text?
What is a benefit of premedication according to the text?
- Increased release of histamine from basophils
- Increase in the likelihood of contrast reactions
- Reduction in the size and complexity of contrast molecules
- Reduction of immediate adverse events from high-osmolality contrast media (correct)
Which type of contrast media is generally associated with less adverse events according to the text?
Which type of contrast media is generally associated with less adverse events according to the text?
- High-osmolality nonionic dimers
- Low-osmolality nonionic monomers (correct)
- Iso-osmolality nonionic dimers
- High-osmolality ionic monomers
Which type of patient population was NOT studied in the randomized trials of premedication?
Which type of patient population was NOT studied in the randomized trials of premedication?
What influence does hyperosmolality of the contrast medium have on the likelihood of contrast reactions?
What influence does hyperosmolality of the contrast medium have on the likelihood of contrast reactions?
What is the estimated number needed to premedicate to prevent one severe reaction in high-risk patients?
What is the estimated number needed to premedicate to prevent one severe reaction in high-risk patients?
Which type of contrast media is generally associated with a reduced likelihood of physiologic reactions following intravenous administration?
Which type of contrast media is generally associated with a reduced likelihood of physiologic reactions following intravenous administration?
What is the potential benefit of premedication for average-risk patients prior to high-osmolality iodinated contrast medium administration?
What is the potential benefit of premedication for average-risk patients prior to high-osmolality iodinated contrast medium administration?
What do many experts believe about the efficacy of premedication in high-risk patients receiving low-osmolality iodinated contrast medium?
What do many experts believe about the efficacy of premedication in high-risk patients receiving low-osmolality iodinated contrast medium?
What was one limitation of the randomized trials of premedication discussed in the text?
What was one limitation of the randomized trials of premedication discussed in the text?
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