Congenital Defects and Scientific Basis

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Questions and Answers

What is the meaning of the term 'congenital'?

  • Present at birth (correct)
  • Acquired after birth
  • Caused by environmental factors
  • Caused by genetic factors

What is an 'anomaly' in the context of congenital defects?

  • A developmental delay
  • A behavioral deviation from the norm
  • A structural deviation from the norm (correct)
  • A functional deviation from the norm

What is the difference between genotype and phenotype?

  • Genotype refers to observable features, while phenotype refers to genetic constitution
  • Genotype refers to genetic constitution, while phenotype refers to observable features (correct)
  • Genotype and phenotype are synonymous terms
  • Genotype and phenotype are not related to each other

Which of the following is NOT a category of congenital anomalies based on their developmental origin?

<p>Dysfunction (A)</p> Signup and view all the answers

What is a 'sequence' in the context of congenital anomalies?

<p>A single defect leads to a series of consequential defects (D)</p> Signup and view all the answers

Which of the following is NOT a main cause of congenital anomalies?

<p>Maternal age (D)</p> Signup and view all the answers

What percentage of congenital anomalies are estimated to be caused by teratogens?

<p>1-3% (B)</p> Signup and view all the answers

Which of the following is NOT an example of a teratogen that can cause congenital defects?

<p>Maternal exercise (C)</p> Signup and view all the answers

Exposure to teratogens during the embryonic period (2-8 weeks) is most likely to cause:

<p>Structural defects (C)</p> Signup and view all the answers

Talipes, or clubfoot, is an example of a congenital:

<p>Malformation (B)</p> Signup and view all the answers

Amniotic bands are most likely to cause which type of congenital anomaly?

<p>Disruption (C)</p> Signup and view all the answers

DiGeorge Syndrome is caused by a deletion on which chromosome?

<p>Chromosome 22 (D)</p> Signup and view all the answers

What does CHARGE in CHARGE Syndrome stand for?

<p>Coloboma, Heart defects, Atresia choanae, Retarded growth, Genital abnormalities, Ear abnormalities (B)</p> Signup and view all the answers

In which region of the spinal cord is Spina bifida most commonly found?

<p>Lumbar (B)</p> Signup and view all the answers

What is particularly affected by alcohol during fetal development?

<p>Neural crest cell migration and brain development (D)</p> Signup and view all the answers

What is the approximate incidence of Fetal Alcohol Syndrome and Alcohol-Related Neurodevelopmental Disorders?

<p>1 in 100 births (B)</p> Signup and view all the answers

What does Congenital Rubella Syndrome primarily affect?

<p>Organs of special senses and heart (A)</p> Signup and view all the answers

What is the primary target of Congenital Rubella Syndrome?

<p>Organs of special senses and heart (C)</p> Signup and view all the answers

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