Podcast
Questions and Answers
What is the potential outcome of venous thrombosis known as?
What is the potential outcome of venous thrombosis known as?
- Pulmonary Embolism (correct)
- Hemorrhage
- Arteriosclerosis
- Aneurysm
Which gene mutation is commonly associated with an increased risk of venous thrombosis in Caucasians?
Which gene mutation is commonly associated with an increased risk of venous thrombosis in Caucasians?
- Antithrombin III mutation
- Factor XIII gene mutation
- Protein C mutation
- Factor V gene mutation (correct)
What diagnostic method is used for detecting pulmonary embolism and other vascular abnormalities?
What diagnostic method is used for detecting pulmonary embolism and other vascular abnormalities?
- Endoscopy
- Doppler ultrasound (correct)
- Echocardiography
- Electrocardiogram
Which laboratory test is recommended for monitoring unfractionated heparin (UFH) and low molecular weight heparins (LMWHs)?
Which laboratory test is recommended for monitoring unfractionated heparin (UFH) and low molecular weight heparins (LMWHs)?
What is the Leiden mutation associated with in terms of clotting risk?
What is the Leiden mutation associated with in terms of clotting risk?
Which factor is not typically tested in laboratory evaluation for thrombotic disorders?
Which factor is not typically tested in laboratory evaluation for thrombotic disorders?
Which of the following drugs has efficacy for non Q wave, Non STEMI, and unstable angina?
Which of the following drugs has efficacy for non Q wave, Non STEMI, and unstable angina?
Which enzyme is needed to activate clopidogrel, and is estimated to be low in 2-14% of the US population?
Which enzyme is needed to activate clopidogrel, and is estimated to be low in 2-14% of the US population?
What is the timeframe within which platelet aggregation is restored after cessation of eptifibatide infusion?
What is the timeframe within which platelet aggregation is restored after cessation of eptifibatide infusion?
Which drug is a nonpeptide IIbIIIa inhibitor given before and after angioplasty or atherectomy?
Which drug is a nonpeptide IIbIIIa inhibitor given before and after angioplasty or atherectomy?
What is the mechanism of action of eptifibatide and tirofiban in inhibiting platelet aggregation?
What is the mechanism of action of eptifibatide and tirofiban in inhibiting platelet aggregation?
What is the main concern regarding the adverse effects of Aspirin?
What is the main concern regarding the adverse effects of Aspirin?
Which drug interaction with Aspirin can lead to increased bleeding?
Which drug interaction with Aspirin can lead to increased bleeding?
What is the major metabolic pathway for Aspirin?
What is the major metabolic pathway for Aspirin?
Which group of individuals is NOT recommended to receive Aspirin according to the text?
Which group of individuals is NOT recommended to receive Aspirin according to the text?
What is a common adverse effect associated with Aspirin use in asthmatics?
What is a common adverse effect associated with Aspirin use in asthmatics?
What is one of the therapeutic uses of Aspirin as mentioned in the text?
What is one of the therapeutic uses of Aspirin as mentioned in the text?
What is the main function of Abciximab (ReoPro) in preventing platelet aggregation?
What is the main function of Abciximab (ReoPro) in preventing platelet aggregation?
Why must GP IIB/IIIA receptor antagonists like Tirofiban be given by continuous infusion?
Why must GP IIB/IIIA receptor antagonists like Tirofiban be given by continuous infusion?
Which of the following statements about Dipyridamole is TRUE?
Which of the following statements about Dipyridamole is TRUE?
How does aspirin-dipyridamole (Aggrenox®) help in preventing CVA after stroke/TIA?
How does aspirin-dipyridamole (Aggrenox®) help in preventing CVA after stroke/TIA?
Which factor may reverse the effects of an overdose of Abciximab (ReoPro)?
Which factor may reverse the effects of an overdose of Abciximab (ReoPro)?
Why should Abciximab (ReoPro) not be used if CrCl is less than 10mL/min?
Why should Abciximab (ReoPro) not be used if CrCl is less than 10mL/min?
What is the function of PRAXBIND (IDARUCIZUMAB)?
What is the function of PRAXBIND (IDARUCIZUMAB)?
Which adverse reaction is associated with the administration of PRAXBIND?
Which adverse reaction is associated with the administration of PRAXBIND?
What is the primary target of Vorapaxar (Zontivity)?
What is the primary target of Vorapaxar (Zontivity)?
Why is Vorapaxar contraindicated in patients with a history of intracranial bleeds or stroke?
Why is Vorapaxar contraindicated in patients with a history of intracranial bleeds or stroke?
How does the half-life of Vorapaxar compare to that of PRAXBIND (IDARUCIZUMAB)?
How does the half-life of Vorapaxar compare to that of PRAXBIND (IDARUCIZUMAB)?
Which type of drug interaction affects the exposure of Vorapaxar?
Which type of drug interaction affects the exposure of Vorapaxar?
What is the main function of Tissue Factor Pathway Inhibitor?
What is the main function of Tissue Factor Pathway Inhibitor?
Which platelet receptor is involved in platelet adhesion to exposed collagen?
Which platelet receptor is involved in platelet adhesion to exposed collagen?
What stimulates the formation of a primary hemostatic plug on the platelet surface?
What stimulates the formation of a primary hemostatic plug on the platelet surface?
Which molecule is important for platelet aggregation along with ADP and thrombin?
Which molecule is important for platelet aggregation along with ADP and thrombin?
Which enzyme is synthesized by endothelial cells and activates the extrinsic clotting cascade?
Which enzyme is synthesized by endothelial cells and activates the extrinsic clotting cascade?
What is the role of GpIIb-IIIa receptors in platelet aggregation?
What is the role of GpIIb-IIIa receptors in platelet aggregation?
What is the main metabolic pathway for Clopidogrel (Plavix)?
What is the main metabolic pathway for Clopidogrel (Plavix)?
Which CYP2C19 inhibitor can decrease the action of Clopidogrel on platelets?
Which CYP2C19 inhibitor can decrease the action of Clopidogrel on platelets?
What is the main therapeutic use of Prasugrel (Effient)?
What is the main therapeutic use of Prasugrel (Effient)?
Which adverse effect is a black box warning associated with the use of Prasugrel?
Which adverse effect is a black box warning associated with the use of Prasugrel?
Why should Prasugrel be avoided in patients with cerebrovascular disease or aged over 75?
Why should Prasugrel be avoided in patients with cerebrovascular disease or aged over 75?
What class of drugs should be monitored when initiating treatment with Prasugrel to avoid adverse effects?
What class of drugs should be monitored when initiating treatment with Prasugrel to avoid adverse effects?
Which drug is used for prevention of CVA after stroke/TIA and may be used for myocardial stress testing?
Which drug is used for prevention of CVA after stroke/TIA and may be used for myocardial stress testing?
Why must GP IIB/IIIA receptor antagonists be given by continuous infusion?
Why must GP IIB/IIIA receptor antagonists be given by continuous infusion?
Which drug is a Fab fragment of a human monoclonal antibody with a duration of action lasting 18-24 hours?
Which drug is a Fab fragment of a human monoclonal antibody with a duration of action lasting 18-24 hours?
What happens if major bleeding occurs while using Abciximab (ReoPro)?
What happens if major bleeding occurs while using Abciximab (ReoPro)?
What is the primary mechanism of action of GP IIB/IIIA receptor antagonists like Eptifibatide and Tirofiban?
What is the primary mechanism of action of GP IIB/IIIA receptor antagonists like Eptifibatide and Tirofiban?
Why should Aspirin-Dipyridamole (Aggrenox®) not be used if CrCl is less than 10mL/min?
Why should Aspirin-Dipyridamole (Aggrenox®) not be used if CrCl is less than 10mL/min?
Why should Betrixaban not be used in patients with non-valvular atrial fibrillation?
Why should Betrixaban not be used in patients with non-valvular atrial fibrillation?
Which medication is used as an antidote for Betrixaban (Bevyxxa) in case of overdose?
Which medication is used as an antidote for Betrixaban (Bevyxxa) in case of overdose?
What is the recommended duration of Betrixaban (Bevyxxa) therapy for deep vein thrombosis (DVT) prophylaxis?
What is the recommended duration of Betrixaban (Bevyxxa) therapy for deep vein thrombosis (DVT) prophylaxis?
Which medication should have its dose reduced when co-administered with P-glycoprotein inhibitors like quinidine and ketoconazole?
Which medication should have its dose reduced when co-administered with P-glycoprotein inhibitors like quinidine and ketoconazole?
What is the effective half-life of Betrixaban (Bevyxxa)?
What is the effective half-life of Betrixaban (Bevyxxa)?
How long does it take for PRAXBIND (IDARUCIZUMAB) to achieve complete anticoagulation reversal?
How long does it take for PRAXBIND (IDARUCIZUMAB) to achieve complete anticoagulation reversal?
Which adverse reaction is NOT associated with the administration of PRAXBIND (IDARUCIZUMAB)?
Which adverse reaction is NOT associated with the administration of PRAXBIND (IDARUCIZUMAB)?
What is the primary target of Vorapaxar (Zontivity)?
What is the primary target of Vorapaxar (Zontivity)?
Which enzyme is estimated to be low in 2-14% of the US population and is needed to activate clopidogrel?
Which enzyme is estimated to be low in 2-14% of the US population and is needed to activate clopidogrel?
What is a potential side effect of Vorapaxar (Zontivity) administration?
What is a potential side effect of Vorapaxar (Zontivity) administration?
What is the circulating half-life of Vorapaxar (Zontivity)?
What is the circulating half-life of Vorapaxar (Zontivity)?
Flashcards are hidden until you start studying
