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Questions and Answers
Which compartments are included in the peripheral compartments of the compartment model?
Which compartments are included in the peripheral compartments of the compartment model?
- Rapidly equilibrating and slowly equilibrating peripheral volumes (correct)
- Central, rapidly equilibrating, and slowly equilibrating peripheral volumes
- Central and rapidly equilibrating peripheral volumes
- Central and slowly equilibrating peripheral volumes
What does the central compartment represent in the compartment model?
What does the central compartment represent in the compartment model?
- A proportionality constant relating the plasma drug concentration at steady state to the total amount of drug in the body
- A volume of distribution that includes all tissues and organs in the body
- A distribution volume including the rapidly mixing portion of the blood and first-pass pulmonary uptake (correct)
- A clearance rate between the central and peripheral compartments
What is the apparent volume of distribution at steady state (Vdss) in the compartment model?
What is the apparent volume of distribution at steady state (Vdss) in the compartment model?
- The proportionality constant relating the plasma drug concentration at steady state to the total amount of drug in the body
- The sum of the central and peripheral compartment volumes
- The volume of distribution that includes all tissues and organs in the body
- The sum of the central, rapidly equilibrating, and slowly equilibrating peripheral compartment volumes (correct)
What are the fundamental parameters of the compartment model?
What are the fundamental parameters of the compartment model?
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What do the clearances represent in the compartment model?
What do the clearances represent in the compartment model?
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Что представляет собой центральный отсек в модели отсеков?
Что представляет собой центральный отсек в модели отсеков?
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Какие параметры являются основными в модели отсеков?
Какие параметры являются основными в модели отсеков?
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Что представляют собой клиренсы в модели отсеков?
Что представляют собой клиренсы в модели отсеков?
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Какие отсеки входят в периферические отсеки модели отсеков?
Какие отсеки входят в периферические отсеки модели отсеков?
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