Comparison of Septic Arthritis, Viral Arthritis, and Reactive Arthritis

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What is the characteristic feature of septic arthritis?

Presence of neutrophils and organism

Which virus can lead to viral arthritis?

Herpes simplex virus

How does septic arthritis primarily differ from viral arthritis?

Neutrophils are found in septic arthritis

What distinguishes reactive arthritis from septic and viral arthritis?

<p>Triggered by a previous infection in another part of the body</p> Signup and view all the answers

Which type of arthritis involves an immune-mediated response?

<p>Viral arthritis</p> Signup and view all the answers

Which organism is commonly associated with septic arthritis?

<p>Staphylococcus aureus</p> Signup and view all the answers

Which aspect differentiates rheumatoid arthritis from viral arthritis?

<p>Rheumatoid arthritis is immune-mediated while viral arthritis is not</p> Signup and view all the answers

What distinguishes osteoarthritis from viral arthritis?

<p>Degenerative nature of osteoarthritis</p> Signup and view all the answers

What is reactive arthritis characterized by?

<p>Immune-mediated response</p> Signup and view all the answers

What distinguishes reactive arthritis from septic arthritis?

<p>Presence of neutrophils and organisms</p> Signup and view all the answers

Which inflammatory condition is a result of an immune-mediated response?

<p>Rheumatoid arthritis</p> Signup and view all the answers

Which organism is commonly associated with reactive arthritis?

<p>Neisseria gonorrhoeae</p> Signup and view all the answers

What characterizes the inflammation in reactive arthritis?

<p>Immune-mediated response without specific organisms</p> Signup and view all the answers

How does reactive arthritis primarily differ from viral arthritis?

<p>Immune-mediated vs. viral etiology</p> Signup and view all the answers

Which type of arthritis involves an immune-mediated response?

<p>(RA) Rheumatoid arthritis</p> Signup and view all the answers

(RA) Rheumatoid arthritis is primarily characterized by:

<p>(RA) Is immune-mediated and involves inflammation.</p> Signup and view all the answers

What distinguishes reactive arthritis from septic and osteoarthritis?

<p>Autoimmune response vs. bacterial infection</p> Signup and view all the answers

What is the characteristic feature of reactive arthritis?

<p>Inflammation in multiple joints</p> Signup and view all the answers

How does reactive arthritis primarily differ from septic arthritis?

<p>Reactive arthritis typically follows an infection in another part of the body, while septic arthritis is a result of bacteria entering the joint space directly.</p> Signup and view all the answers

What feature distinguishes reactive arthritis from both septic and viral arthritis?

<p>Genetic predisposition (HLA-B27)</p> Signup and view all the answers

Which histocompatibility antigen is associated with reactive arthritis?

<p>HLA-B27</p> Signup and view all the answers

What is the second most common cause of reactive arthritis?

<p>Chlamydia trachomatis infection</p> Signup and view all the answers

In reactive arthritis, what differentiates the joint pain and inflammation presentation?

<p>Symptoms of the initial infection are present</p> Signup and view all the answers

What is a common misconception about reactive arthritis compared to septic arthritis?

<p>Reactive arthritis presents with acute onset of joint pain and fever, similar to septic arthritis.</p> Signup and view all the answers

Which of the following gastrointestinal pathogens is NOT associated with reactive arthritis?

<p>Cryptosporidium</p> Signup and view all the answers

Which aspect of reactive arthritis is not shared with septic arthritis?

<p>Symptoms of initial infection present like diarrhea or urinary symptoms</p> Signup and view all the answers

What distinguishes reactive arthritis from septic arthritis?

<p>Symptoms in multiple joints</p> Signup and view all the answers

What distinguishes reactive arthritis from viral arthritis in terms of joint pain presentation?

<p>Asymmetric joint pain involving lower extremities</p> Signup and view all the answers

What is the characteristic feature of reactive arthritis?

<p>Presence of neutrophils and viral organism</p> Signup and view all the answers

How does reactive arthritis primarily differ from osteoarthritis?

<p>Immune-mediated response</p> Signup and view all the answers

Which organism is commonly associated with reactive arthritis?

<p>Salmonella</p> Signup and view all the answers

What distinguishes reactive arthritis from septic arthritis?

<p>Presence of neutrophils and viral organism</p> Signup and view all the answers

How does reactive arthritis primarily differ from rheumatoid arthritis?

<p>Immune-mediated response vs. viral organism</p> Signup and view all the answers

What characterizes the inflammation in reactive arthritis?

<p>Presence of neutrophils and organism</p> Signup and view all the answers

Study Notes

Arthritis

  • Arthritis is an inflammation of the joints, affecting one or multiple joints
  • Over 100 types of arthritis exist, with different causes and treatment methods
  • Two common types: osteoarthritis (OA) and rheumatoid arthritis (RA)
    • Osteoarthritis: degenerative
    • Rheumatoid arthritis: immune-mediated

Types of Arthritis

  • Septic arthritis: inflammation of a joint due to bacterial infection
  • Viral arthritis: inflammation of a joint due to viral infection
  • Reactive arthritis: inflammation of a joint due to infection, usually in the gastrointestinal or genitourinary tract

Comparative Features of Arthritis

  • Septic arthritis
    • Bacterial infection, usually Staphylococcus aureus or Streptococcus species
    • Symptoms: acute onset of joint pain, swelling, warmth, and decreased range of motion; fever and chills common
    • Risk factors: previous joint damage, prosthetic joints, immunosuppression, intravenous drug use, or skin infections
  • Viral arthritis
    • Viral infection, such as hepatitis, parvovirus, or rubella
    • Symptoms: joint pain, swelling, and stiffness, often accompanied by symptoms of the underlying viral illness
    • Risk factors: exposure to viruses through travel or contact with infected individuals
  • Reactive arthritis
    • Inflammation of a joint due to infection, usually in the gastrointestinal or genitourinary tract
    • Symptoms: joint pain and inflammation, often asymmetric and involving lower extremities
    • Risk factors: genetic predisposition (HLA-B27), contact with infected individuals, or family history

Osteomyelitis

  • Inflammatory process in the bone and bone marrow accompanied by bone destruction
  • Usually due to bacterial infection
  • Most common in the metaphysis of long bones, less frequent in upper extremities
  • Causes: hematogenous spread from distant focus, such as Staphylococcus aureus, Streptococcus pyogenes, and Haemophilus influenzae
  • Salmonella infection often associated with sickle cell anemia

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