Comparison of FCZ and KCZ in Ocular Penetration and Antifungal Spectrum
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Questions and Answers

What is the primary therapy for fungal keratitis according to the passage?

  • New-generation triazoles
  • Second-generation triazoles
  • Polyenes (correct)
  • Imidazoles

    • Which of the following is a broad-spectrum antifungal according to the passage?

  • Itraconazole
  • Miconazole (correct)
  • Econazole
  • Posaconazole

    • What is the mechanism of action of imidazoles according to the passage?

  • They act on cytochrome P450 enzymes
  • They inhibit catalase and cytochrome C peroxidase, leading to cell death
  • They block the synthesis of ergosterol in the plasma membrane
  • They affect the formation of ergosterol in cell membranes and disrupt lysosomes (correct)

    • What is the main advantage of triazoles over polyenes according to the passage?

    <p>Triazoles have a broader spectrum of activity and fewer side effects</p> Signup and view all the answers

    What is the primary use of econazole according to the passage?

    <p>Treatment of superficial mycosis</p> Signup and view all the answers

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