Comparison of B-cell and T-cell epitopes in allergen

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What is the purpose of the Allergome platform?

Integrating data related to allergens (correct)

Predicting allergenic proteins

Collecting sequence information for tumor antigens

Identifying B cell epitopes in allergic diseases

Which publication discusses relevant B cell epitopes in allergic disease?

Blood 1980; 55:607–11

Int Arch Allergy Immunol 2010; 152:1–11 (correct)

Virus Res 2009; 141:90–5

Immunol Today 1997; 18:267–8

What does SDAP provide according to the text?

Model for collecting sequence information of tumor antigens

Tools for allergenicity prediction (correct)

Database of evolutionary relationships of genes and proteins in the human immune system

Information on conserved B-cell epitopes

In which publication is there a discussion on tumor antigens and proteomics?

Mol Cell Proteomics 2003; 2:388–98 Signup and view all the answers

What is the focus of ImmTree database?

Evolutionary relationships of genes and proteins in the human immune system Signup and view all the answers

Which publication introduces a database for allergenic proteins and tools for allergenicity prediction?

Bioinformation 2009; 3:344–5 Signup and view all the answers

What is the basis of the allergen prediction method proposed by Kong et al.?

Identification of allergen motifs in a given protein sequence Signup and view all the answers

What did Zorzet et al. introduce in their computational approach for classifying amino acid sequences?

Use of SVM and a similarity-based approach Signup and view all the answers

What is the purpose of ALGPRED created by Saha and Raghava?

Analysis using SVM and a similarity-based approach Signup and view all the answers

How did Stadler and Stadler identify relevant motifs present in allergen sequences?

Using the MEME motif discovery tool Signup and view all the answers

What criterion is used to consider a sequence as an allergenic sequence in the method by Stadler and Stadler?

Scoring better than an E-value of 10^8 in pairwise alignment Signup and view all the answers

In the allergen prediction method by Kong et al., what was the motif length and motif number used to develop the database?

Motif length of 35 amino acids and motif number of 500 Signup and view all the answers

What is the main difference between T-cell epitopes and B-cell epitopes?

T-cell epitopes are linear, while B-cell epitopes can be either linear or conformational. Signup and view all the answers

Which database provides information related to 2434 allergens across categories like rice microbes, animals, and plants?

ALLERGEN PRO database Signup and view all the answers

What type of data does ALLERGOME 4.0 provide an exhaustive repository of?

IgE-binding compound data Signup and view all the answers

Which tool in ALLERGOME 4.0 allows users to upload raw data from both in vivo and in vitro experiments?

ReTiME Signup and view all the answers

What makes predicting allergenicity based on known conformational epitopes a difficult task for B-cell epitopes?

Difficulty in identifying conformational epitopes Signup and view all the answers

In which database can one find the ALLERGEN NOMENCLATURE and ALLERGEN PRO databases?

IUIS database Signup and view all the answers

Comparison of B-cell and T-cell epitopes in allergen

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