Comparing RR, PR, OR, and POR in Epidemiology
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Questions and Answers

In which type of study is the OR preferred over the RR and PR for estimating the relative measure of association?

  • Cohort study
  • Case-control study (correct)
  • Longitudinal study
  • Cross-sectional study
  • When is the exposure E considered a potential protective factor for the disease D based on the relative measure of association?

  • $ \text{Relative measure} \geq 1 $
  • $ \text{Relative measure} = 1 $
  • $ \text{Relative measure} < 1 $ (correct)
  • $ \text{Relative measure} > 1 $
  • What does PR stand for in the context of estimating relative measures of association?

  • Proportional Risk
  • Potential Risk
  • Prevalence Ratio (correct)
  • Population Ratio
  • When is the exposure E and the disease D considered independent based on the relative measure of association?

    <p>$ \text{Relative measure} = 1 $ (D)</p> Signup and view all the answers

    In which type of study would the risk ratio (RR) compare the probability of developing the disease during the follow-up between two groups of exposure?

    <p>Cohort study (D)</p> Signup and view all the answers

    Why are POR and OR treated as numerically identical in cross-sectional and case-control studies?

    <p>They yield the same results in specific cases (A)</p> Signup and view all the answers

    What is the population attributable risk (PAR)?

    <p>PAR is a measure of impact and represents the proportion of cases in the population which are attributable to the exposure (C)</p> Signup and view all the answers

    What does the population attributable risk (PAR) measure assume?

    <p>All of the above (D)</p> Signup and view all the answers

    What does the population attributable risk (PAR) measure assume if P(D|Ē) = 0?

    <p>PAR = 1 (D)</p> Signup and view all the answers

    What is the exposure attributable risk (EAR)?

    <p>EAR measures the proportion of cases among the exposed population that are attributable to the exposure (A)</p> Signup and view all the answers

    Which package in R can be used to calculate confidence intervals for odds ratio and risk ratio?

    <p>epiR (C)</p> Signup and view all the answers

    What are the possible values for RR compared to OR?

    <p>RR &gt; 1 . OR &gt; RR RR &lt; 1 . OR &lt; RR RR = 1 . OR = 1 (D)</p> Signup and view all the answers

    In which type of study is the prevalence ratio (PR) compared between two groups of exposure?

    <p>Cross-sectional study (A)</p> Signup and view all the answers

    What does the logistic regression model interpret in terms of odds ratio?

    <p>Coefficients have a straightforward interpretation in terms of odds ratio. (A)</p> Signup and view all the answers

    What does OR stand for in statistics?

    <p>(Odds Ratio) (B)</p> Signup and view all the answers

    Which distribution is used for the exact calculation of confidence intervals for odds ratio in high sample size scenarios?

    <p>&quot;hypergeometric distribution&quot; (A)</p> Signup and view all the answers

    "The lower P(D|E) and P(D|Ē), the closer RR and OR." Which type of diseases usually exhibit this characteristic?

    <p>&quot;Rare diseases&quot; (A)</p> Signup and view all the answers

    What do PR, RR, and OR measure?

    <p>PR measures impact, while RR and OR measure association. (A)</p> Signup and view all the answers

    What is the formula for calculating Attributable Numbers (ANp) in epidemiology?

    <p>ANp = AFp * np (B)</p> Signup and view all the answers

    In epidemiology, what are attributable fractions usually reported as to describe the impact of the exposure?

    <p>% to the exposed population (A)</p> Signup and view all the answers

    What is the formula for calculating the number of cases among the whole population that would not have occurred in the absence of exposure (ANp) in epidemiology?

    <p>ANp = AFp * np (D)</p> Signup and view all the answers

    In the context of epidemiology, which measure is known as 'excess risk'?

    <p>Attributable Numbers (AN) (C)</p> Signup and view all the answers

    What does EAR stand for in the context of estimating health impacts in epidemiology?

    <p>Exposure Attributable Risk (C)</p> Signup and view all the answers

    What is known as excess risk in epidemiology?

    <p>P(D|E) P(D|Ē) (D)</p> Signup and view all the answers

    What is used to describe the impact of exposure in epidemiology?

    <p>Attributable Fractions (AF) (B)</p> Signup and view all the answers

    Flashcards

    When is OR preferred?

    The Odds Ratio (OR) is preferred over the Risk Ratio (RR) and Prevalence Ratio (PR) for estimating the relative measure of association in Case-Control studies.

    Protective factor

    The exposure E is considered a potential protective factor for the disease D if the relative measure of association is less than 1.

    What is PR?

    PR stands for Prevalence Ratio, which is a measure of the association between exposure and disease in cross-sectional studies.

    Independence

    The exposure E and disease D are considered independent if the relative measure of association equals 1.

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    RR in Cohort Study

    In a Cohort study, the Risk Ratio (RR) compares the probability of developing the disease during the follow-up period between two groups with different exposure status.

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    When are POR and OR equal?

    In cross-sectional and case-control studies, the Prevalence Odds Ratio (POR) and Odds Ratio (OR) yield the same results because of specific conditions.

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    What is PAR?

    PAR, or Population Attributable Risk, measures the proportion of cases in a population that can be attributed to exposure to a risk factor.

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    Assumptions of PAR

    The PAR assumes that there is a causal relationship between exposure and disease, and that the presence of the exposure is a modifiable risk factor.

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    PAR = 1

    If the probability of disease in the unexposed group is 0, then the PAR would be 1, meaning all cases in the population can be attributed to exposure.

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    What is EAR?

    EAR, or Exposure Attributable Risk, measures the proportion of cases among the exposed population that can be attributed to the exposure.

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    epiR for Confidence Intervals

    The epiR package in R can be used to calculate confidence intervals for odds ratio and risk ratio, providing statistical accuracy for estimations.

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    Comparing RR and OR

    The values of RR and OR can be compared based on the direction and magnitude of the association. If RR > 1, then OR > RR. If RR < 1, then OR < RR. And if RR = 1, then OR = 1.

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    PR in Cross-Sectional Study

    In a Cross-sectional study, the Prevalence Ratio (PR) is compared between two groups with different exposure status.

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    Logistic Regression and OR

    In logistic regression models, the coefficients directly interpret the odds ratio.

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    What is OR?

    OR stands for Odds Ratio, a measure of association between an exposure and an outcome.

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    Distribution for OR Confidence Intervals

    The hypergeometric distribution is used to calculate exact confidence intervals for odds ratio in scenarios with large sample sizes.

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    OR and RR for Rare Diseases

    Rare diseases typically exhibit the characteristic that the lower the probabilities of disease in exposed and unexposed groups, the closer the RR and OR.

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    What do PR, RR and OR measure?

    PR measures the impact of exposure on the population, while RR and OR measure the association between exposure and disease, reflecting the relative risk.

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    Attributable Numbers Formula

    The formula for calculating Attributable Numbers (ANp) in epidemiology is ANp = AFp * np where AFp is the attributable fraction and np is the number of people in the population.

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    Attributable Fractions Reporting

    Attributable fractions are usually reported as a percentage to the exposed population, providing information about the impact of the exposure.

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    ANp Formula

    The formula for calculating Attributable Numbers (ANp) is ANp = AFp * np, where AFp is the attributable fraction and np is the population size.

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    What is 'Excess Risk'?

    Attributable Numbers (AN) is a measure of 'excess risk' representing the difference in disease incidence between exposed and unexposed groups, highlighting the impact of exposure.

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    What is EAR?

    EAR stands for Exposure Attributable Risk, a measure of the proportion of cases among the exposed population that are attributable to the exposure.

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    What is 'Excess Risk'?

    The excess risk in epidemiology is defined as the difference between the probability of disease in the exposed group and the probability of disease in the unexposed group, represented by P(D|E) - P(D|Ē).

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    What are Attributable Fractions?

    Attributable Fractions (AF) are used to describe the impact of exposure, quantifying the proportion of cases that can be attributed to the exposure.

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