Common Rheumatologic and Autoimmune Diseases and Related Medications Quiz
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Questions and Answers

At what age range does the peak number of hip fractures occur for both sexes?

  • 70-74 years
  • 50-54 years
  • 60-64 years
  • 75-79 years (correct)

What percentage of men over the age of 50 globally are affected by osteoporosis?

  • 12.8%
  • 18.7%
  • 1.5%
  • 6.3% (correct)

How often do vertebral fractures caused by osteoporosis occur worldwide in men and women over 50?

  • Every 15 seconds
  • Every 20 seconds
  • Every 25 seconds
  • Every 22 seconds (correct)

What is the projected increase in worldwide incidence of hip fracture in men by 2050 compared to rates in 1990?

<p>310% (D)</p> Signup and view all the answers

What role do healthy bones play in the body?

<p>Storing and supplying calcium, protecting vital organs, and providing space for bone marrow (A)</p> Signup and view all the answers

At what age does bone mass reach its peak?

<p>40 (B)</p> Signup and view all the answers

What factor accelerates the process of bone mass decline?

<p>A combination of genetics, hormonal status, physical activity, medication, and medical conditions (C)</p> Signup and view all the answers

What percentage of women over the age of 50 globally are affected by osteoporosis?

<p>&gt;20% (D)</p> Signup and view all the answers

What is the main function of bone marrow?

<p>Producing red and white blood cells (A)</p> Signup and view all the answers

What is the impact of osteoporosis on bone fractures for women over the age of 50 compared to men?

<p>+15% (B)</p> Signup and view all the answers

Which of the following is NOT a common form of primary osteoporosis?

<p>Juvenile osteoporosis (C)</p> Signup and view all the answers

What is the main cause of postmenopausal osteoporosis?

<p>Deficiency of estrogen (D)</p> Signup and view all the answers

What is the primary function of osteoclasts in the bone remodeling cycle?

<p>Resorption of old or damaged bone tissue (C)</p> Signup and view all the answers

What type of fracture is associated with osteoporosis?

<p>Fragility fracture (A)</p> Signup and view all the answers

How often is the adult skeleton replaced through the bone remodeling cycle?

<p>Every 10 years (A)</p> Signup and view all the answers

What is the main characteristic of secondary osteoporosis?

<p>Caused by medical conditions, medications, and lifestyle changes (B)</p> Signup and view all the answers

Which medical condition is NOT associated with secondary osteoporosis?

<p>Hypertension (D)</p> Signup and view all the answers

What factor almost doubles the risk of a future fracture in older people?

<p>Previous fracture (A)</p> Signup and view all the answers

What is the main impact of fragility fractures on older people?

<p>Significantly impacted quality of life due to pain and disability (B)</p> Signup and view all the answers

What approach can help prevent fragility fractures in older people?

<p>Developing a falls prevention care plan for individuals at risk of falls and fractures (D)</p> Signup and view all the answers

Which phase of the bone remodeling cycle involves resorption?

<p>Resorption phase (B)</p> Signup and view all the answers

What triggers the activation of the resorption process in the bone remodeling cycle?

<p>RankL pathway activation by osteoblasts (C)</p> Signup and view all the answers

In osteoporosis, fragility fractures are most likely to result from which of the following?

<p>A fall from standing height or less (B)</p> Signup and view all the answers

What is the main characteristic of primary osteoporosis?

<p>Low bone density and microarchitectural deterioration (B)</p> Signup and view all the answers

Which is the most common form of osteoporosis?

<p>Postmenopausal osteoporosis (A)</p> Signup and view all the answers

What is the main goal of bone health assessment in older people?

<p>To identify individuals at risk of developing fractures (C)</p> Signup and view all the answers

Which medical conditions can cause secondary osteoporosis?

<p>Ankylosing spondylitis and rheumatoid arthritis (A)</p> Signup and view all the answers

What promotes bone loss during the resorption phase of the bone remodeling cycle?

<p>&quot;Destruction of bone tissue&quot; (D)</p> Signup and view all the answers

"Fragility fractures" in older people are associated with increased morbidity and mortality, primarily due to:

<p>&quot;Pain and disability&quot; (B)</p> Signup and view all the answers

"Screening for osteoporosis" is an important measure for preventing fragility fractures because it helps in:

<p>&quot;Identifying individuals at risk of fractures&quot; (A)</p> Signup and view all the answers

What is the purpose of the fracture risk assessment tool (FRAX)?

<p>To assess the probability of incurring a hip or other major osteoporotic fracture over a 10 year period. (A)</p> Signup and view all the answers

What does the fracture risk assessment tool (FRAX) require clinicians to enter to estimate fracture probability?

<p>Height and weight, medication history, smoking history, family history, and bone mass density (optional) (A)</p> Signup and view all the answers

Which laboratory investigation is associated with increased bone turnover and elevated levels in primary hyperparathyroidism?

<p>Parathyroid Hormone (PTH) (B)</p> Signup and view all the answers

What is the main purpose of the DXA radiology investigation?

<p>To diagnose osteoporosis based on T score and bone mineral density (BMD). (A)</p> Signup and view all the answers

Why is it important to ask about the patient's diet, alcohol, and smoking history in the assessment of bone health?

<p>To identify potential risk factors for osteoporosis (D)</p> Signup and view all the answers

What should be examined during the physical examination to assess bone health?

<p>Posture, rheumatoid arthritis, and muscle strength (B)</p> Signup and view all the answers

Which risk factor is used by the fracture risk assessment tool (FRAX) to estimate the probability of fracture?

<p>Previous fracture (B)</p> Signup and view all the answers

What do clinicians need to examine for in terms of posture during a bone health examination?

<p>Any curvature (scoliosis) of the spine (C)</p> Signup and view all the answers

What should be entered into the fracture risk assessment tool (FRAX) as part of clinical risk factors?

<p>Age, sex, weight, previous fracture, parent fractured hip, current smoking, glucocorticoids, rheumatoid arthritis (A)</p> Signup and view all the answers

What should laboratory investigations include as part of the bone profile examination?

<p>Calcium, phosphate, magnesium, albumin and alkaline phosphatase (B)</p> Signup and view all the answers

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