Introduction to Rheumatology HUD02-3005

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Questions and Answers

What is the primary cell type responsible for osteoclast production in the joint space in rheumatoid arthritis?

  • T cells
  • B cells
  • Monocytes (correct)
  • Macrophages

Which of the following complications is commonly associated with rheumatoid arthritis?

  • Sickle cell anemia
  • Thalassemia
  • Normochromic, normocytic anemia (correct)
  • Hemolytic anemia

What is the main cause of Atlanto-axial subluxation in rheumatoid arthritis?

  • Rupture of neck muscles
  • Degeneration of cervical vertebrae
  • Erosion of the odontoid process and/or transverse ligaments (correct)
  • Erosion of the spinal cord

Which treatment is specifically mentioned for mild to moderate rheumatoid arthritis?

<p>DMARDs like methotrexate and hydroxychloroquine (C)</p> Signup and view all the answers

What type of nodule is described as necrotizing granulomas in rheumatoid arthritis?

<p>Subcutaneous nodules (B)</p> Signup and view all the answers

Which complication can lead to digital gangrene in individuals with rheumatoid arthritis?

<p>Vasculitis (D)</p> Signup and view all the answers

What is a common symptom seen in Sjogren’s syndrome?

<p>Dryness of mouth, eyes, skin, vagina (C)</p> Signup and view all the answers

Which autoimmune disease is commonly associated with Sjogren’s syndrome?

<p>Rheumatoid arthritis (C)</p> Signup and view all the answers

In Sjogren’s syndrome, what gland may present as swollen?

<p>Parotid gland (A)</p> Signup and view all the answers

What is the characteristic tongue appearance seen in Sjogren’s syndrome?

<p>Smooth, lobulated tongue (C)</p> Signup and view all the answers

Which condition is associated with an increased risk of lymphoma/Maltoma?

<p>Sjogren’s syndrome (B)</p> Signup and view all the answers

What diagnostic test is used to assess the level of tear production in Sjogren’s syndrome?

<p>Schirmer test (B)</p> Signup and view all the answers

Which autoimmune disease is characterized by dry eyes and dry mouth?

<p>Sjogren’s Syndrome (B)</p> Signup and view all the answers

What is the specific autoantibody profile that can assist in the diagnosis of connective tissue diseases?

<p>Anti-CCP (Anti-Cyclic Citrullinated Peptide) (A)</p> Signup and view all the answers

Which autoimmune disease affects the skin causing hardening and tightening of the skin and connective tissues?

<p>Scleroderma (D)</p> Signup and view all the answers

What is the main focus of disease management for rheumatoid arthritis?

<p>Controlling inflammation and preventing joint damage (D)</p> Signup and view all the answers

Which autoimmune disease primarily affects the joints and causes symmetrical joint pain and swelling?

<p>Rheumatoid arthritis (C)</p> Signup and view all the answers

How do autoantibody profiles contribute to the diagnosis of connective tissue diseases?

<p>By reacting with specific antigens present in these diseases (D)</p> Signup and view all the answers

What is the relevance of Focal lymphocytic sialadenitis (FLS) to dentistry?

<p>Causes dry mouth leading to dental caries and tooth loss (A)</p> Signup and view all the answers

Which investigation has largely replaced Sialography & Scintigraphy?

<p>Ultrasound (D)</p> Signup and view all the answers

What pathology is associated with Lupus Erythematosus?

<p>Widespread vasculitis of capillaries, arterioles, and venules (B)</p> Signup and view all the answers

Which symptom is NOT typically associated with cerebral micro-infarcts in SLE?

<p>Skin rash (A)</p> Signup and view all the answers

What is the percentage of patients with SLE that will develop some degree of renal involvement?

<p>5% (A)</p> Signup and view all the answers

Which condition is characterized by scarring skin lesions or oral lesions?

<p>Discoid Lupus (DLE) (C)</p> Signup and view all the answers

What is a common symptom of lupus erythematosus that is relevant to dentistry?

<p>Oral ulceration (B)</p> Signup and view all the answers

Which manifestation is NOT typically associated with scleroderma?

<p>Recurrent foetal loss (C)</p> Signup and view all the answers

What reversible skin color change is associated with Raynaud’s phenomenon?

<p>White to blue to red (D)</p> Signup and view all the answers

Which medication is commonly used in the treatment of Raynaud’s phenomenon?

<p>Nifedipine (B)</p> Signup and view all the answers

Which condition involves degenerative disease of cartilage and is often affected by mechanical insults?

<p>Osteoarthritis (C)</p> Signup and view all the answers

What is a common complication of systemic treatment in relation to lupus erythematosus?

<p>+/-Dry mouth (C)</p> Signup and view all the answers

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