Introduction to Rheumatology HUD02-3005

Play an AI-generated podcast conversation about this lesson

What is the primary cell type responsible for osteoclast production in the joint space in rheumatoid arthritis?

T cells

B cells

Monocytes (correct)

Macrophages

Which of the following complications is commonly associated with rheumatoid arthritis?

Sickle cell anemia

Thalassemia

Normochromic, normocytic anemia (correct)

Hemolytic anemia

What is the main cause of Atlanto-axial subluxation in rheumatoid arthritis?

Rupture of neck muscles

Degeneration of cervical vertebrae

Erosion of the odontoid process and/or transverse ligaments (correct)

Erosion of the spinal cord

Which treatment is specifically mentioned for mild to moderate rheumatoid arthritis?

DMARDs like methotrexate and hydroxychloroquine Signup and view all the answers

What type of nodule is described as necrotizing granulomas in rheumatoid arthritis?

Subcutaneous nodules Signup and view all the answers

Which complication can lead to digital gangrene in individuals with rheumatoid arthritis?

Vasculitis Signup and view all the answers

What is a common symptom seen in Sjogren’s syndrome?

Dryness of mouth, eyes, skin, vagina Signup and view all the answers

Which autoimmune disease is commonly associated with Sjogren’s syndrome?

Rheumatoid arthritis Signup and view all the answers

In Sjogren’s syndrome, what gland may present as swollen?

Parotid gland Signup and view all the answers

What is the characteristic tongue appearance seen in Sjogren’s syndrome?

Smooth, lobulated tongue Signup and view all the answers

Which condition is associated with an increased risk of lymphoma/Maltoma?

Sjogren’s syndrome Signup and view all the answers

What diagnostic test is used to assess the level of tear production in Sjogren’s syndrome?

Schirmer test Signup and view all the answers

Which autoimmune disease is characterized by dry eyes and dry mouth?

Sjogren’s Syndrome Signup and view all the answers

What is the specific autoantibody profile that can assist in the diagnosis of connective tissue diseases?

Anti-CCP (Anti-Cyclic Citrullinated Peptide) Signup and view all the answers

Which autoimmune disease affects the skin causing hardening and tightening of the skin and connective tissues?

Scleroderma Signup and view all the answers

What is the main focus of disease management for rheumatoid arthritis?

Controlling inflammation and preventing joint damage Signup and view all the answers

Which autoimmune disease primarily affects the joints and causes symmetrical joint pain and swelling?

Rheumatoid arthritis Signup and view all the answers

How do autoantibody profiles contribute to the diagnosis of connective tissue diseases?

By reacting with specific antigens present in these diseases Signup and view all the answers

What is the relevance of Focal lymphocytic sialadenitis (FLS) to dentistry?

Causes dry mouth leading to dental caries and tooth loss Signup and view all the answers

Which investigation has largely replaced Sialography & Scintigraphy?

Ultrasound Signup and view all the answers

What pathology is associated with Lupus Erythematosus?

Widespread vasculitis of capillaries, arterioles, and venules Signup and view all the answers

Which symptom is NOT typically associated with cerebral micro-infarcts in SLE?

Skin rash Signup and view all the answers

What is the percentage of patients with SLE that will develop some degree of renal involvement?

5% Signup and view all the answers

Which condition is characterized by scarring skin lesions or oral lesions?

Discoid Lupus (DLE) Signup and view all the answers

What is a common symptom of lupus erythematosus that is relevant to dentistry?

Oral ulceration Signup and view all the answers

Which manifestation is NOT typically associated with scleroderma?

Recurrent foetal loss Signup and view all the answers

What reversible skin color change is associated with Raynaud’s phenomenon?

White to blue to red Signup and view all the answers

Which medication is commonly used in the treatment of Raynaud’s phenomenon?

Nifedipine Signup and view all the answers

Which condition involves degenerative disease of cartilage and is often affected by mechanical insults?

Osteoarthritis Signup and view all the answers

What is a common complication of systemic treatment in relation to lupus erythematosus?

+/-Dry mouth Signup and view all the answers