Introduction to Rheumatology HUD02-3005
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Questions and Answers

What is the primary cell type responsible for osteoclast production in the joint space in rheumatoid arthritis?

  • T cells
  • B cells
  • Monocytes (correct)
  • Macrophages
  • Which of the following complications is commonly associated with rheumatoid arthritis?

  • Sickle cell anemia
  • Thalassemia
  • Normochromic, normocytic anemia (correct)
  • Hemolytic anemia
  • What is the main cause of Atlanto-axial subluxation in rheumatoid arthritis?

  • Rupture of neck muscles
  • Degeneration of cervical vertebrae
  • Erosion of the odontoid process and/or transverse ligaments (correct)
  • Erosion of the spinal cord
  • Which treatment is specifically mentioned for mild to moderate rheumatoid arthritis?

    <p>DMARDs like methotrexate and hydroxychloroquine</p> Signup and view all the answers

    What type of nodule is described as necrotizing granulomas in rheumatoid arthritis?

    <p>Subcutaneous nodules</p> Signup and view all the answers

    Which complication can lead to digital gangrene in individuals with rheumatoid arthritis?

    <p>Vasculitis</p> Signup and view all the answers

    What is a common symptom seen in Sjogren’s syndrome?

    <p>Dryness of mouth, eyes, skin, vagina</p> Signup and view all the answers

    Which autoimmune disease is commonly associated with Sjogren’s syndrome?

    <p>Rheumatoid arthritis</p> Signup and view all the answers

    In Sjogren’s syndrome, what gland may present as swollen?

    <p>Parotid gland</p> Signup and view all the answers

    What is the characteristic tongue appearance seen in Sjogren’s syndrome?

    <p>Smooth, lobulated tongue</p> Signup and view all the answers

    Which condition is associated with an increased risk of lymphoma/Maltoma?

    <p>Sjogren’s syndrome</p> Signup and view all the answers

    What diagnostic test is used to assess the level of tear production in Sjogren’s syndrome?

    <p>Schirmer test</p> Signup and view all the answers

    Which autoimmune disease is characterized by dry eyes and dry mouth?

    <p>Sjogren’s Syndrome</p> Signup and view all the answers

    What is the specific autoantibody profile that can assist in the diagnosis of connective tissue diseases?

    <p>Anti-CCP (Anti-Cyclic Citrullinated Peptide)</p> Signup and view all the answers

    Which autoimmune disease affects the skin causing hardening and tightening of the skin and connective tissues?

    <p>Scleroderma</p> Signup and view all the answers

    What is the main focus of disease management for rheumatoid arthritis?

    <p>Controlling inflammation and preventing joint damage</p> Signup and view all the answers

    Which autoimmune disease primarily affects the joints and causes symmetrical joint pain and swelling?

    <p>Rheumatoid arthritis</p> Signup and view all the answers

    How do autoantibody profiles contribute to the diagnosis of connective tissue diseases?

    <p>By reacting with specific antigens present in these diseases</p> Signup and view all the answers

    What is the relevance of Focal lymphocytic sialadenitis (FLS) to dentistry?

    <p>Causes dry mouth leading to dental caries and tooth loss</p> Signup and view all the answers

    Which investigation has largely replaced Sialography & Scintigraphy?

    <p>Ultrasound</p> Signup and view all the answers

    What pathology is associated with Lupus Erythematosus?

    <p>Widespread vasculitis of capillaries, arterioles, and venules</p> Signup and view all the answers

    Which symptom is NOT typically associated with cerebral micro-infarcts in SLE?

    <p>Skin rash</p> Signup and view all the answers

    What is the percentage of patients with SLE that will develop some degree of renal involvement?

    <p>5%</p> Signup and view all the answers

    Which condition is characterized by scarring skin lesions or oral lesions?

    <p>Discoid Lupus (DLE)</p> Signup and view all the answers

    What is a common symptom of lupus erythematosus that is relevant to dentistry?

    <p>Oral ulceration</p> Signup and view all the answers

    Which manifestation is NOT typically associated with scleroderma?

    <p>Recurrent foetal loss</p> Signup and view all the answers

    What reversible skin color change is associated with Raynaud’s phenomenon?

    <p>White to blue to red</p> Signup and view all the answers

    Which medication is commonly used in the treatment of Raynaud’s phenomenon?

    <p>Nifedipine</p> Signup and view all the answers

    Which condition involves degenerative disease of cartilage and is often affected by mechanical insults?

    <p>Osteoarthritis</p> Signup and view all the answers

    What is a common complication of systemic treatment in relation to lupus erythematosus?

    <p>+/-Dry mouth</p> Signup and view all the answers

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