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Questions and Answers
Which protein is considered the 'Master' ECM protein?
Which protein is considered the 'Master' ECM protein?
- Collagen IV
- Nidogen
- Laminin (correct)
- Fibrillar Collagen
What are the two primary types of extracellular matrix?
What are the two primary types of extracellular matrix?
- Fibrillar Collagen and Fibronectin (correct)
- Basement Membranes and Tissue Specificity
- Laminin and Collagen IV
- Proteoglycans and Glycosaminoglycans
Which proteins self-assemble to form a sheet-like structure?
Which proteins self-assemble to form a sheet-like structure?
- Collagen IV (correct)
- Laminin
- Fibrillar Collagen
- Nidogen
Which type of ECM contains laminin, collagen IV, heparan sulfate proteoglycan, and nidogen?
Which type of ECM contains laminin, collagen IV, heparan sulfate proteoglycan, and nidogen?
What is the role of nidogen and heparan sulfate proteoglycans in basement membrane assembly?
What is the role of nidogen and heparan sulfate proteoglycans in basement membrane assembly?
Which type of ECM frequently contains cells within it and is characterized by fibrillar collagens, proteoglycans, and glycosaminoglycans?
Which type of ECM frequently contains cells within it and is characterized by fibrillar collagens, proteoglycans, and glycosaminoglycans?
What is the primary producer of connective tissue ECM proteins?
What is the primary producer of connective tissue ECM proteins?
Which cellular organelles assist in the modification and assembly of collagen chains?
Which cellular organelles assist in the modification and assembly of collagen chains?
What is the role of C-propeptides in collagen assembly?
What is the role of C-propeptides in collagen assembly?
What happens to procollagen in the extracellular space?
What happens to procollagen in the extracellular space?
What is the role of Proteoglycans and Glycosaminoglycans (GAGs) in connective tissues?
What is the role of Proteoglycans and Glycosaminoglycans (GAGs) in connective tissues?
Which protein components are essential in every basal lamina?
Which protein components are essential in every basal lamina?
Which type of ECM is required for multi-cellular life?
Which type of ECM is required for multi-cellular life?
What are the major protein components of connective tissue?
What are the major protein components of connective tissue?
How do laminin and collagen IV interact in the basement membrane?
How do laminin and collagen IV interact in the basement membrane?
Which type of cytoskeletal element is composed of actin filaments?
Which type of cytoskeletal element is composed of actin filaments?
Which protein is responsible for the assembly and disassembly of microfilaments?
Which protein is responsible for the assembly and disassembly of microfilaments?
Which cytoskeletal element is involved in cell motility?
Which cytoskeletal element is involved in cell motility?
Which structure is composed of microtubules in a 9+2 array and associated proteins required for structural integrity and movement?
Which structure is composed of microtubules in a 9+2 array and associated proteins required for structural integrity and movement?
What is the function of dynein in the molecular basis of movement?
What is the function of dynein in the molecular basis of movement?
Which drug binds to tubulin and inhibits microtubule assembly?
Which drug binds to tubulin and inhibits microtubule assembly?
Which cytoskeletal component is dynamic and can undergo continuous assembly and disassembly in the cell?
Which cytoskeletal component is dynamic and can undergo continuous assembly and disassembly in the cell?
What is the main type of protein subunits that form microtubules?
What is the main type of protein subunits that form microtubules?
Which cytoskeletal component is characterized by a diameter of 10 nm and stability?
Which cytoskeletal component is characterized by a diameter of 10 nm and stability?
Which proteins regulate the structure and function of F-actin in all cell types?
Which proteins regulate the structure and function of F-actin in all cell types?
Which gene mutation can cause blistering disorders in the skin?
Which gene mutation can cause blistering disorders in the skin?
What is the function of desmin in the cytoskeleton?
What is the function of desmin in the cytoskeleton?
Which antibody is used as a tumor cell marker for glial cell tumors?
Which antibody is used as a tumor cell marker for glial cell tumors?
What is the basic structural unit of microtubules?
What is the basic structural unit of microtubules?
Which protein is responsible for cross-linking microfilament bundles in surface projections such as microvilli?
Which protein is responsible for cross-linking microfilament bundles in surface projections such as microvilli?
What is the function of stress fibers in cell movement?
What is the function of stress fibers in cell movement?
Which class of myosin contains traditional or conventional myosins such as skeletal and heart muscle myosin?
Which class of myosin contains traditional or conventional myosins such as skeletal and heart muscle myosin?
What is the function of Myosin Light Chain Kinase (MLCK) in the regulation of Myosin II?
What is the function of Myosin Light Chain Kinase (MLCK) in the regulation of Myosin II?
Which protein is responsible for the movement of proteins and organelles along microfilaments?
Which protein is responsible for the movement of proteins and organelles along microfilaments?
What is the main function of intermediate filaments?
What is the main function of intermediate filaments?
Which type of ECM is characterized by fibrillar collagens, proteoglycans, and glycosaminoglycans?
Which type of ECM is characterized by fibrillar collagens, proteoglycans, and glycosaminoglycans?
What is the role of desmosomes in specialized cell contacts?
What is the role of desmosomes in specialized cell contacts?
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