Cognitive Control and Brain Functions
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Questions and Answers

Which part of the brain is primarily involved in maintaining goals in working memory?

  • Frontal pole
  • Lateral prefrontal cortex (correct)
  • Medial prefrontal cortex
  • Parietal cortex

What is essential for goal-directed action in cognitive control?

  • Triggering behaviors without intention
  • Automatic responses to stimuli
  • Immediate response to context
  • Knowledge of the relationship between actions and outcomes (correct)

What function does dynamic filtering serve in cognitive control?

  • Inhibition of unwanted behaviors (correct)
  • Prioritizing irrelevant information
  • Maintaining long-term memories
  • Facilitating automatic responses

Where does conflict monitoring primarily occur in the brain?

<p>Medial prefrontal cortex (B)</p> Signup and view all the answers

What does cognitive control require for behaviors to be influenced by goals?

<p>Voluntary action and planning (D)</p> Signup and view all the answers

What is a characteristic of habits in terms of cognitive control?

<p>They are not influenced by specific goals (A)</p> Signup and view all the answers

What role does the lateral prefrontal cortex play in cognitive control?

<p>Filtering distractions unrelated to goals (B)</p> Signup and view all the answers

Which mechanism of cognitive control allows for shifts in behavior based on changing goals?

<p>Goal-dependent inhibition (A)</p> Signup and view all the answers

What is one function of the anterior cingulate cortex (ACC)?

<p>Monitoring goal achievement (D)</p> Signup and view all the answers

Which task is specifically impaired by lesions in the prefrontal cortex (PFC)?

<p>Delayed-response tasks (C)</p> Signup and view all the answers

During delay-period activity in an oculomotor delayed response task, which neurons are involved?

<p>Lateral PFC neurons (A)</p> Signup and view all the answers

What characteristic of lateral PFC neurons allows them to adapt to changing tasks?

<p>Task-specific selectivity (B)</p> Signup and view all the answers

In an integrative model of goal-directed processing, what does the lateral PFC primarily represent?

<p>Task goals (D)</p> Signup and view all the answers

Which of the following activities does not contribute to the delay-period activity in lateral PFC neurons?

<p>Processing visual sensory input (A)</p> Signup and view all the answers

What role does the posterior cortex play in relation to the lateral PFC?

<p>Representing task-relevant information (C)</p> Signup and view all the answers

How do prefrontal cortex (PFC) lesions affect associative-memory control tasks?

<p>They have no impact (A)</p> Signup and view all the answers

What is one primary function of the anterior cingulate cortex (ACC)?

<p>Monitoring goal achievement (B)</p> Signup and view all the answers

Which task demonstrates the highest level of abstraction in the prefrontal cortex hierarchy?

<p>Context task (C)</p> Signup and view all the answers

What do patients with prefrontal cortex lesions struggle with in relation to action hierarchy?

<p>Establishing subgoals for planning (C)</p> Signup and view all the answers

What aspect of action goals does the prefrontal cortex relate to?

<p>Complexity and abstraction level (B)</p> Signup and view all the answers

In an fMRI study, which task involves mapping colors to texture-response mapping?

<p>Feature task (A)</p> Signup and view all the answers

What is the primary role of the lateral prefrontal cortex?

<p>Maintenance of goals in working memory (C)</p> Signup and view all the answers

What cognitive function primarily involves the medial prefrontal cortex?

<p>Monitoring errors and conflicts (C)</p> Signup and view all the answers

In terms of cognitive control systems, what distinguishes goal-directed behavior from stimulus-response behavior?

<p>Stimulus-response outcomes rely less on working memory. (B)</p> Signup and view all the answers

What type of behavioral deficits may occur due to lesions in the prefrontal cortex?

<p>Complex cognitive control deficits (D)</p> Signup and view all the answers

Which function is primarily associated with the attentional filtering role of the lateral prefrontal cortex?

<p>Shifting between multiple tasks (B)</p> Signup and view all the answers

What is a key feature of working memory as it relates to cognitive control?

<p>It only retains information temporarily. (B)</p> Signup and view all the answers

Which of the following best describes the interaction of the lateral PFC with posterior cortex?

<p>It sustains task goals in working memory using sensory information. (A)</p> Signup and view all the answers

Which region of the brain is primarily responsible for monitoring goal achievement and response conflict?

<p>Anterior cingulate cortex (A)</p> Signup and view all the answers

What is the primary function of lateral PFC in relation to task goals?

<p>Dynamic filtering of information (D)</p> Signup and view all the answers

What happens to the activity in the posterior cortex when task goals are present?

<p>It enhances task-relevant information (A)</p> Signup and view all the answers

Which of the following best describes the effect of lateral PFC lesions on attentional selection?

<p>Reduced enhancement of attended tones (A)</p> Signup and view all the answers

In the context of the stop-signal task, which area activates in response to the stop signal?

<p>Inferior frontal gyrus (B)</p> Signup and view all the answers

What is the role of the subthalamic nucleus in action inhibition?

<p>Facilitating the aborting of responses (B)</p> Signup and view all the answers

Which attentional mechanism describes the lateral PFC's role in information selection?

<p>Dynamic filtering (D)</p> Signup and view all the answers

What primarily influences fMRI activity in category-selective higher-level visual cortex?

<p>Task goals (C)</p> Signup and view all the answers

During successful stop trials in the stop-signal task, which area is likely to exhibit high activation levels?

<p>Motor cortex (A)</p> Signup and view all the answers

Which aspect of cognitive control is primarily managed by the medial prefrontal cortex?

<p>Conflict monitoring (B)</p> Signup and view all the answers

What is the primary function of the lateral prefrontal cortex in cognitive control?

<p>Enhancement and suppression of information according to goals (A)</p> Signup and view all the answers

What role does the anterior cingulate cortex (ACC) play in conflict monitoring?

<p>It detects response conflicts and increases activity in the lateral PFC (C)</p> Signup and view all the answers

Which cognitive control process is associated with the decrease in activity in the cognitive control network before an error occurs?

<p>Error-related negativity (A)</p> Signup and view all the answers

During which task does the medial prefrontal cortex show increased activity due to response conflicts?

<p>Stroop task (D)</p> Signup and view all the answers

What happens to the activity in the default mode network before an error is made?

<p>It increases steadily (D)</p> Signup and view all the answers

What is one of the primary components linked to the medial prefrontal cortex during error detection?

<p>Error-related negativity (B)</p> Signup and view all the answers

Which statement best describes the function of dynamic filtering in cognitive control?

<p>It involves the suppression of irrelevant information based on the current task. (B)</p> Signup and view all the answers

In which area of the brain does goal-directed behavior mainly occur?

<p>Lateral prefrontal cortex (A)</p> Signup and view all the answers

What is indicated by the activity in the ACC after an incongruent trial in the Stroop task?

<p>Increased need for conflict monitoring (B)</p> Signup and view all the answers

What is a common misconception regarding the function of the ACC?

<p>It can detect conflicts even when errors are rare. (D)</p> Signup and view all the answers

Which statement best describes the posterior-to-anterior gradient in the ACC?

<p>It reflects the complexity and abstraction of responses. (D)</p> Signup and view all the answers

In cognitive control tasks, what is the significance of the steady decrease in activity before an error?

<p>It represents preparation for possible conflicts. (B)</p> Signup and view all the answers

What outcome does increased activity in the lateral PFC indicate after the ACC signals a conflict?

<p>Reactivation of the relevant goal in working memory (C)</p> Signup and view all the answers

Flashcards

Cognitive Control

The ability of the brain to manage competing thoughts and actions, allowing us to focus on relevant information and achieve our goals.

Habit

A type of behavior that is triggered automatically by a specific stimulus or context. It's not under conscious control and is influenced by repeated past experiences.

Goal-directed action

A type of behavior that is driven by a conscious goal or desired outcome. It involves planning, considering different options, and actively choosing actions to reach the goal.

Prefrontal Cortex (PFC)

The brain region responsible for higher-level cognitive functions, including planning, decision-making, and goal-directed behavior.

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Lateral prefrontal cortex (PFC)

A part of the PFC that plays a crucial role in maintaining goals in mind, filtering information, and initiating, inhibiting, or switching between actions based on goals.

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Medial Prefrontal Cortex (mPFC)

A part of the PFC that monitors for conflicts between competing thoughts or actions. It helps us stay on track and adjust our behavior when needed.

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Working Memory

The ability of the brain to temporarily store and manipulate information needed for current tasks, such as remembering instructions, planning ahead, or solving problems.

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Dynamic Filtering

The process of selecting relevant information while suppressing irrelevant information in order to achieve a goal.

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Anterior Cingulate Cortex (ACC)

A brain region involved in monitoring and adjusting goal-directed behavior, particularly when there's a conflict or error. It's like the supervisor that checks if you're on the right track and makes corrections if needed.

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Delayed-Response Tasks

Tasks that require holding information in mind over a period of time, even when the information is not currently present in the environment. Like remembering where you parked your car after going shopping.

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Delay Period

The period between a cue and a response in a task that requires holding information in mind. Like the time you spend remembering the code before opening a door.

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Oculomotor Delayed Response (ODR) Task

A task used to study working memory where a participant has to remember a location (e.g., where a light flashed) and then make an eye movement to that location. It's like a mental map for your eyes.

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Lateral PFC Neurons

Neurons in the prefrontal cortex that fire during the delay period in a working memory task, keeping a specific piece of information active in the mind. Imagine them as tiny mental spotlights.

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Flexibility of PFC Neurons

The ability of the prefrontal cortex to adapt and represent different types of information, allowing it to flexibly handle various tasks. It's like having mental toolboxes for different jobs.

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Integrative Model of Goal-Directed Processing

A model suggesting that the prefrontal cortex represents the goal of a task while posterior brain regions (like sensory areas) provide the relevant information needed to reach the goal. It's like having a brain with both a commander (PFC) and soldiers (posterior areas).

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What is the role of the anterior cingulate cortex (ACC) in goal achievement?

The anterior cingulate cortex (ACC) plays a crucial role in monitoring goal achievement by detecting errors, responding to negative feedback, managing response conflicts, and registering surprise. It helps us stay on track and adapt to changing situations.

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How does the prefrontal cortex (PFC) organize action goals?

The PFC has a hierarchical structure, with regions further back (posterior) handling simpler tasks and regions further forward (anterior) engaging in more complex processes. This gradient reflects the increasing complexity of action goals.

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How does the PFC contribute to action planning?

During goal-directed behavior, the PFC helps organize actions into a hierarchical structure, creating a plan of subgoals that lead to the ultimate goal. This process involves anticipating consequences and identifying the requirements for achieving each subgoal.

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What happens to action planning when the prefrontal cortex (PFC) is damaged?

Patients with PFC lesions often struggle with planning tasks. This suggests the PFC's crucial role in creating and executing action plans.

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How does fMRI evidence support the hierarchical structure of the PFC?

A fMRI study showed that different areas of the PFC are activated depending on the complexity of a task. As tasks became more abstract or involved higher-level reasoning, anterior regions of the PFC showed greater activity.

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What does the ACC monitor?

The anterior cingulate cortex (ACC) monitors goal achievement by detecting errors, negative feedback, response conflict, and surprising events.

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How does the ACC influence cognitive control?

The ACC modulates how much cognitive control is needed and how it should be used.

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What does the lateral PFC hold onto?

The lateral PFC maintains a sustained representation of the current task goal.

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What does the posterior cortex represent?

The posterior cortex (higher-level sensory areas) represent information relevant to the task, including stimuli and long-term memory knowledge.

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How does the lateral PFC filter information?

The lateral PFC dynamically filters information based on current goals, acting like an attentional mechanism in the posterior cortex.

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How does the posterior cortex handle information?

The posterior cortex inhibits irrelevant information and enhances relevant information, based on goals set by the lateral PFC.

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How do task goals affect the posterior cortex?

Task goals influence the fMRI activity in the posterior cortex, specifically in category-selective higher-level visual areas.

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What happens with lateral PFC lesions?

Lateral PFC lesions lead to deficits in filtering, resulting in reduced suppression of irrelevant tones and reduced enhancement of attended tones in ERPs (P100).

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How does rTMS to the lateral PFC affect attention?

Repetitive TMS (rTMS) to the lateral PFC reduces attentional modulation of the P100 in feature-based attention tasks.

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What happens in the brain when you need to stop an action?

The inferior frontal gyrus is activated when a stop signal is presented, regardless of whether the response is successfully stopped or not.

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Prefrontal Cortex

The region of the brain responsible for executive functions like planning, working memory, and goal-directed behavior, influencing behavior based on goals rather than immediate stimuli or context.

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Complex Cognitive Control Deficits

Inability to effectively plan and execute actions toward a goal, often characterized by repetitive behaviors and difficulty adapting to changes in the environment; a consequence of prefrontal cortex damage.

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Environmental Dependency Syndrome

A condition where individuals are highly influenced by the environment, often engaging in imitative or environmentally driven actions, demonstrating a lack of internal goal direction.

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Medial Prefrontal Cortex (incl. ACC)

A part of the prefrontal cortex responsible for monitoring cognitive processes, detecting errors and conflicts, and evaluating feedback, contributing to adaptive control by adjusting the level of cognitive effort as needed.

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Error-Related Negativity (ERN)

Brainwaves detected using an electroencephalogram (EEG) that follow incorrect responses. It's a signal associated with error detection.

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Feedback-Related Negativity (FRN)

Brainwaves detected using EEG that follow feedback about errors. It reflects the processing of error information and potential adjustments.

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Default Mode Network

The brain's automatic shift to a state of internal reflection before an error occurs, potentially related to surprise or conflict.

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Stroop Task

A classic test of cognitive control that involves naming the ink color of written words, where the word itself is a conflicting color name.

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ACC-to-Lateral PFC Signal

Increased activity in the ACC due to conflicting information (like the Stroop task) triggers increased activity in the lateral PFC, helping reactivate the goal and overcome the conflict.

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Posterior-to-Anterior Hierarchy in Lateral PFC

A hierarchical structure within the lateral PFC, with more posterior regions handling simpler actions and more anterior regions managing complex, abstract goals.

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Posterior-to-Anterior Hierarchy in ACC

A similar hierarchical structure exists in the ACC, where more posterior regions monitor basic actions and more anterior regions manage complex goals.

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ACC Conflict Control

The ACC's ability to control conflict between potential responses.

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Action Inhibition

The brain's ability to control actions, involving inhibition of unwanted behaviors.

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Functional Magnetic Resonance Imaging (fMRI)

A method for studying brain activity where a subject performs a cognitive task while their brain responses are measured using magnetic fields.

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Study Notes

Cognitive Control Overview

  • Cognitive control involves the prefrontal cortex (PFC) and is essential for directing behavior based on goals rather than solely reacting to stimuli.
  • Working memory within cognitive control involves holding information active in mind for processing.
  • Dynamic filtering and inhibition mechanisms in the PFC allow selective focus on relevant information while suppressing distractions.
  • A hierarchy of goals exists within the PFC, with different levels of complexity demanding varying degrees of cognitive control.
  • Monitoring in the medial PFC, especially the anterior cingulate cortex (ACC), detects errors, processes feedback, and adjusts cognitive control accordingly.

Prefrontal Control Systems

  • Goal-directed behavior relies on the lateral PFC (frontal pole) for maintaining goals, filtering information, and planning complex actions.
  • Conflict monitoring in the medial PFC (ACC) detects errors, processes feedback, and adjusts cognitive control accordingly.

Delayed-Response Tasks

  • Tasks require retaining stimulus attributes over a delay period, which is critical for working memory and is impaired by PFC lesions.
  • Associative memory tasks involving a cue-reward association aren't affected by PFC lesions.

Delay-Period Activity

  • Lateral PFC neurons persistently fire during the delay period of a task, holding relevant information actively in mind.
  • Delay-period activity is seen for various attributes and response modalities.

PFC Interactions with Posterior Cortex

  • A model of goal-directed processing integrates PFC-mediated goal representation with posterior cortical sensory processing.

Dynamic Filtering & Suppression

  • Task goals in the lateral PFC influence posterior cortex activity, enhancing relevant and suppressing irrelevant information.
  • Category-specific enhancement and suppression of task-relevant information is observed compared to passive viewing, indicating selectivity.
  • Lateral PFC plays a crucial role in attentional selection, affecting filtering processes.

Inhibition of Action

  • Stop-signal tasks involve responding to a stimulus and inhibiting the response when a stop signal occurs shortly afterward.
  • The right inferior frontal gyrus is typically activated during stop-signal tasks, involved in response inhibition.

Conflict Monitoring

  • The Stroop task, a study of conflict monitoring, highlights the process of inhibiting irrelevant stimuli's activation when generating a response.
  • The ACC, particularly during incongruent trials, shows increased activity in conflict situations.
  • Activation in the ACC triggers increased activity in the lateral PFC, reactivating the current goal in working memory..

Error Detection & Negative Feedback

  • Activity in the cognitive control network (including the medial and lateral PFC) decreases steadily before an error.
  • Activity in the default mode network (like the precuneus) increases before an error.
  • Predicting errors demonstrates a shift between cognitive control and default mode networks.

Action Hierarchy

  • Making plans, anticipation of consequences and planning for multiple goals are essential for successfully achieving subgoals, which is impaired by PFC lesions.
  • A hierarchy of subgoals and planning abilities are crucial to achieve complex goals, which is impaired in patients with PFC lesions.

Prefrontal Cortex Hierarchy

  • A study using nested tasks that increase in complexity and abstractness indicated that the PFC has a hierarchical organization according to goal complexity.
  • The posterior PFC handles stimulus response and simple mappings while the anterior PFC handles increasingly complex mappings over time.

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Description

This quiz explores the intricate relationships between cognitive control and various functions of the brain. It covers topics such as working memory, goal-directed action, and the roles of specific brain regions like the lateral prefrontal cortex and the anterior cingulate cortex. Test your knowledge of cognitive control mechanisms and their implications for behavior.

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