Cocaine and Cocaethylene Quiz

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Which of the following effects does cocaethylene have compared to cocaine?

Increased euphoric effect (correct)

Shorter half-life

Less toxic

Weaker vasoconstrictor

Cocaethylene acts as a strong depressant of the nervous system.

False

What is the primary neurotransmitter whose reuptake cocaine blocks?

Dopamine

Cocaethylene has a half-life of approximately _____ minutes in the body.

150 Signup and view all the answers

Match the following effects with their corresponding categories related to cocaine and cocaethylene:

Increased heart rate = Activation of the sympathetic nervous system Euphoria = Pharmacological effects Local anesthetic = Mechanism of action Vasoconstriction = Mechanism of action Signup and view all the answers

What is a common effect of high doses of cocaine?

Agitation and anxiety Signup and view all the answers

Cocaine use can lead to persistent euphoria and increased judgment.

False Signup and view all the answers

What physiological impact can cocaine have on newborns if the mother uses it during pregnancy?

Low birth weight and congenital anomalies Signup and view all the answers

The acute toxic dose of cocaine is approximately _____ mg/kg.

2 Signup and view all the answers

Match the following effects with the respective substance:

Cocaine = Rapid crossover to placenta affecting newborns Amphetamines = Impairment of attentiveness and emotional expressivity Both = Potential for addiction and withdrawal symptoms Signup and view all the answers

What is the primary neurotransmitter that psychostimulants augment?

Dopamine Signup and view all the answers

Cocaine is synthesized from the leaves of the coca plant.

True Signup and view all the answers

What is the half-life of cocaine in plasma?

about 50 minutes Signup and view all the answers

Cocaine that is soluble in alcohol, acetone, or ether is known as __________.

crack cocaine Signup and view all the answers

Match the following forms of cocaine with their characteristics:

Crack Cocaine = Insoluble in water but soluble in alcohol Cocaine HCl = Water-soluble and used for local anesthesia Smoked Cocaine = Effects peak at 5 minutes Intravenous Cocaine = Immediate entry into bloodstream Signup and view all the answers

What percentage of a snorted dose of cocaine is absorbed through the nasal mucosa?

20 to 30% Signup and view all the answers

Cocaine is slowly removed from the brain, taking 8 or more hours after initial use.

True Signup and view all the answers

What is the major metabolite of cocaine detected in urine?

benzoylecgonine Signup and view all the answers

What is the half-life of cocaine?

30-90 minutes Signup and view all the answers

Amphetamines act as local anesthetics.

False Signup and view all the answers

What neurotransmitters does amphetamine primarily affect?

Dopamine and norepinephrine Signup and view all the answers

At high doses, amphetamine can prevent dopamine degradation by binding to _____ .

monoamine oxidase (MAO) Signup and view all the answers

Match the pharmacological effects of low to moderate doses of amphetamine with their descriptions:

Increased blood pressure = Stimulates cardiovascular activity Relaxed bronchial muscle = Facilitates easier breathing Increased alertness = Enhances cognitive function Loss of appetite = Reduces the desire to eat Signup and view all the answers

Which of the following is a characteristic of high-dose amphetamine use?

Increased euphoria Signup and view all the answers

Amphetamine metabolites can be detected in urine for up to 72 hours after consumption.

False Signup and view all the answers

What potential impact does amphetamine use have during athletic competitions?

Enhanced performance, but impaired fine motor skills Signup and view all the answers

What is a notable challenge in identifying the effects of drug use during pregnancy?

Separation from other contributing factors Signup and view all the answers

Withdrawal syndrome from opioids is usually more dramatic than from other substances.

False Signup and view all the answers

At what age do children display higher scores for anxiety, depression, and aggression due to exposure to drugs in pregnancy?

3 years old Signup and view all the answers

Symptoms of withdrawal can include increased appetite, weight gain, and a need for increased _____ .

sleep Signup and view all the answers

Match the symptoms with their corresponding effects associated with opioid withdrawal:

Increased appetite = Physical withdrawal symptom Decreased energy = Physical withdrawal symptom Paranoid symptoms = Psychological withdrawal symptom Severe depression = Psychological withdrawal symptom Signup and view all the answers

What is the primary route of administration for the crystalline form of methamphetamine known as 'ice'?

Smoking Signup and view all the answers

Methamphetamine has a relatively short half-life of about 3 hours.

False Signup and view all the answers

What are two health risks associated with high doses of methamphetamine?

Cardiac toxicity and paranoid delusions Signup and view all the answers

The metabolic process of methamphetamine results in about _____ percent being metabolized in the liver.

60 Signup and view all the answers

Match the following potential effects of methamphetamine use with their descriptions:

Acute Psychotic Behavior = Severe alterations in perception and reality Cardiac Toxicity = Increased risk of heart-related complications Parkinson's Disease predisposition = Slower motor function and memory deficits Stereotypical Behaviors = Repetitive actions often seen in stimulant use Signup and view all the answers

Cocaine and Cocaethylene Quiz

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Questions and Answers

Which of the following effects does cocaethylene have compared to cocaine?

Cocaethylene acts as a strong depressant of the nervous system.

What is the primary neurotransmitter whose reuptake cocaine blocks?

Cocaethylene has a half-life of approximately _____ minutes in the body.

Match the following effects with their corresponding categories related to cocaine and cocaethylene:

What is a common effect of high doses of cocaine?

Cocaine use can lead to persistent euphoria and increased judgment.

What physiological impact can cocaine have on newborns if the mother uses it during pregnancy?

The acute toxic dose of cocaine is approximately _____ mg/kg.

Match the following effects with the respective substance:

What is the primary neurotransmitter that psychostimulants augment?

Cocaine is synthesized from the leaves of the coca plant.

What is the half-life of cocaine in plasma?

Cocaine that is soluble in alcohol, acetone, or ether is known as __________.

Match the following forms of cocaine with their characteristics:

What percentage of a snorted dose of cocaine is absorbed through the nasal mucosa?

Cocaine is slowly removed from the brain, taking 8 or more hours after initial use.

What is the major metabolite of cocaine detected in urine?

What is the half-life of cocaine?

Amphetamines act as local anesthetics.

What neurotransmitters does amphetamine primarily affect?

At high doses, amphetamine can prevent dopamine degradation by binding to _____ .

Match the pharmacological effects of low to moderate doses of amphetamine with their descriptions:

Which of the following is a characteristic of high-dose amphetamine use?

Amphetamine metabolites can be detected in urine for up to 72 hours after consumption.

What potential impact does amphetamine use have during athletic competitions?

What is a notable challenge in identifying the effects of drug use during pregnancy?

Withdrawal syndrome from opioids is usually more dramatic than from other substances.

At what age do children display higher scores for anxiety, depression, and aggression due to exposure to drugs in pregnancy?

Symptoms of withdrawal can include increased appetite, weight gain, and a need for increased _____ .

Match the symptoms with their corresponding effects associated with opioid withdrawal:

What is the primary route of administration for the crystalline form of methamphetamine known as 'ice'?

Methamphetamine has a relatively short half-life of about 3 hours.

What are two health risks associated with high doses of methamphetamine?

The metabolic process of methamphetamine results in about _____ percent being metabolized in the liver.

Match the following potential effects of methamphetamine use with their descriptions:

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