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Coagulation System Functions Quiz

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Questions and Answers

Which of the following plasma components is not part of the coagulation system?

Fibrinogen substrate

Anticoagulants

Erythrocytes (correct)

Procoagulants

What is the primary purpose of the coagulation cascade?

To generate thrombin and produce fibrin for a localized thrombus (correct)

To activate platelets and initiate primary hemostasis

To regulate anticoagulant pathways and prevent excessive clotting

To increase the levels of acute phase reactants like fibrinogen and prothrombin

Which of the following is not considered a procoagulant in the coagulation system?

Antithrombin (correct)

Factor VIII

Fibrinogen

Prothrombin

What is the role of tissue factor (TF) in the coagulation cascade?

TF activates factor VII, which then activates factors IX and X Signup and view all the answers

What is the function of the factor IXa:VIIIa complex in the coagulation cascade?

It activates factor X Signup and view all the answers

Which coagulation factor is responsible for stabilizing the fibrin clot?

Factor XIII Signup and view all the answers

What is the role of the factor Xa:Va complex in the coagulation cascade?

It activates prothrombin to thrombin Signup and view all the answers

What is the role of the anticoagulant protein, tissue factor pathway inhibitor (TFPI)?

TFPI inhibits the activation of factor X by the tissue factor/factor VIIa complex Signup and view all the answers

Which of the following is not a positive feedback mechanism in the coagulation cascade?

Antithrombin inhibiting the activity of thrombin Signup and view all the answers

Why are fibrinogen, prothrombin, and factor VIII considered acute phase reactants?

Their levels increase during inflammation, trauma, pregnancy, and stress Signup and view all the answers