Exam 19 - Disorders Associated with Plts, Clotting, Plasma

An anticoagulant used to prevent blood clots.

A condition with fewer than 150,000 platelets/mm3.

Small red or purple spots on the skin indicative of bleeding disorders.

Bruising caused by bleeding underneath the skin.

Vital signs indicating low blood volume or shock.

Test to measure different components of blood, including platelets.

A test to check for immature platelets or abnormalities in bone marrow.

Gradually reducing blood-thinning medication under healthcare supervision.

Reduced levels of proteins necessary for blood clotting, leading to thrombosis and bleeding.

Formation of small clots in blood vessels, causing reduced blood flow to organs and potential damage.

Symptoms including bleeding from multiple sites, cold digits, and signs of end-organ damage.

Tests indicating DIC include prolonged PT/PTT, positive D-dimer, and decreased fibrinogen.

Management includes addressing the underlying cause, controlling bleeding, and replacing lost blood components.

Conditions affecting blood clotting mechanisms, leading to abnormal bleeding.

Trauma, vessel damage, liver disease, and disturbances in platelet function.

A series of reactions involving platelets and clotting factors to form a clot.

The initial plug formed by platelets at a site of blood vessel injury.

Sign and symptoms that indicate a coagulation disorder, like bleeding and pallor.

Small red or purple spots (petechiae) and larger bruises (ecchymosis) on the skin.

Lower than normal blood pressure, often seen in circulatory hypovolemia.

A blood test measuring red blood cells, platelets, and hemoglobin levels.

Medication used to prevent blood clots by inhibiting clotting factors.

Liver impairment that can disrupt production of clotting factors.

Observation of organs affected by disease or treatment processes.

Immunoglobulin produced by myeloma cells; marker for disease extent.

Malignant disease of bone marrow with tumor formation.

Older adults, peaks around 65, affects more men than women.

Imaging tests used to diagnose bone-related diseases.

Test to examine bone marrow for diseases like myeloma.

Drugs like Vincristine, Doxorubicin used to treat myeloma.

High calcium levels in blood, a risk in multiple myeloma.

Includes complaints of pain, temperature, and bleeding potential.

A condition characterized by the lack of blood clotting factors VIII and/or IX, leading to bleeding disorders.

A blood test that measures the time it takes for blood to clot; prolonged PTT indicates a coagulation issue.

Medical management includes transfusions or treatment with Factor VIII to address clotting deficiencies.

An inherited bleeding disorder caused by a deficiency in factor VIII leading to easy bruising and bleeding.

A blood product rich in clotting factors, including factor VIII, used for treating bleeding disorders.

A serious disorder involving clotting and bleeding due to the overstimulation of coagulation processes.

A medication used to treat mild hemophilia and von Willebrand's disease by increasing factor VIII levels.

Thrombosis refers to abnormal blood clot formation, while fibrinolysis is the process of breaking down clots.

A process to help patients and families understand genetic conditions and implications for bleeding disorders.

Methods like immobilization, applying pressure, and using ice to control bleeding in urgent situations.