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Questions and Answers

What is the function of fibrin in the blood clotting process?

To form a solid plug in the blood vessels

To circulate in the blood in high concentration

To act as a mesh to hold the platelet plug together (correct)

To activate platelets at the site of injury

Which factor is responsible for converting fibrinogen to fibrin?

Prothrombin

Fibrin

Thrombin (correct)

Platelets

What is the role of platelets in the blood clotting process?

To convert fibrinogen to fibrin

To form a plug at the site of vessel injury (correct)

To activate thrombin

To circulate in the blood in high concentration

What initiates the complex cascade involving 13 factors in the blood clotting process?

Activation of 1 factor catalyzing the activation of the next Signup and view all the answers

Which factor is formed from Factor V by previously activated thrombin?

Factor Va Signup and view all the answers

What does thrombin activate to crosslink the fibrin strands together to form the clot at the end?

Factor XIII Signup and view all the answers

In which pathway does the tissue factor serve as the 'spark' activated by initial injury?

Extrinsic pathway Signup and view all the answers

What is the importance of thrombin in the blood clotting process?

Activates Factor XI and Factor XIII Signup and view all the answers

Which deficiency is associated with the formation of Thrombophilia?

Factor V Signup and view all the answers

What is the result of mutations near F8 that may lead to Haemophilia A?

A null allele (no working product) Signup and view all the answers

Which factor deficiency is associated with Haemophilia B?

Factor IX Signup and view all the answers

What does Factor XIII activate in the blood clotting process?

Crosslinks Signup and view all the answers