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Questions and Answers

Which of the following brainstem structures is primarily responsible for relaying signals related to breathing?

  • Pons (correct)
  • Cerebellum
  • Midbrain
  • Medulla

Which of the following regions regulates homeostasis, hormones, hunger and thirst?

  • Basal Ganglia
  • Limbic System
  • Thalamus
  • Hypothalamus (correct)

Damage to Broca's area typically results in what type of aphasia?

  • Sensory aphasia
  • Fluent aphasia
  • Non-fluent aphasia (correct)
  • Global aphasia

Which type of sensory receptor is responsible for detecting changes in temperature?

<p>Thermoreceptors (B)</p>
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What is the correct order of the signal transduction pathway?

<p>Stimulus → receptor → threshold → graded potential → action potential (D)</p>
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Which of the following is a characteristic of tonic receptors?

<p>Slow adaptation (D)</p>
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Which of the following best describes the pathway of olfaction?

<p>Chemoreceptors → olfactory bulb → olfactory cortex (D)</p>
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Place the components of the hearing pathway in the correct order.

<p>Sound → tympanic membrane → cochlea → vestibulocochlear nerve → brain (D)</p>
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Which of the following accurately describes the visual pathway?

<p>Light → retina → optic nerve → thalamus → visual cortex (C)</p>
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Which of the following characterizes the sympathetic nervous system?

<p>Thoracolumbar origin, short preganglionic fibers, uses NE (A)</p>
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Which neurotransmitter is used by the parasympathetic nervous system?

<p>Acetylcholine (ACh) (A)</p>
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What does the adrenal medulla secrete?

<p>Epinephrine (A)</p>
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Which division of the nervous system directly controls skeletal muscle using Acetylcholine (ACh)?

<p>Somatic Motor Division (D)</p>
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Which hormone class is exemplified by insulin?

<p>Peptide (D)</p>
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Steroid hormones typically bind to receptors located where?

<p>Intracellular/nuclear (C)</p>
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Which hormones are secreted by the posterior pituitary gland?

<p>Oxytocin, ADH (B)</p>
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What type of feedback loop involves the end hormone inhibiting the hypothalamus or pituitary gland?

<p>Long-loop (C)</p>
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Which of the following is an example of a direct physiological feedback loop?

<p>Insulin and PTH (B)</p>
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Which of the following is NOT a formed element of blood?

<p>Albumin (A)</p>
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What is the primary function of hemoglobin?

<p>Binding oxygen (D)</p>
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Which of the following represents the correct sequence of events in hemostasis?

<p>Vasoconstriction → platelet plug → coagulation → fibrinolysis (A)</p>
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Which component of the heart's electrical system directly precedes the Purkinje fibers in the sequence of depolarization?

<p>Bundle of His (A)</p>
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On an ECG, what does the QRS complex represent?

<p>Ventricular depolarization (B)</p>
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How does sympathetic autonomic control affect heart rate?

<p>Increases heart rate (B)</p>
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Which of the following represents the correct sequence of blood flow through the vascular system?

<p>Arteries → Arterioles → Capillaries → Venules → Veins (B)</p>
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How is Mean Arterial Pressure (MAP) calculated?

<p>DP + 1/3(PP) (A)</p>
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Which bodily function does the baroreceptor reflex primarily respond to?

<p>Changes in blood pressure (D)</p>
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Which of the following is a function of the respiratory system?

<p>Gas exchange (D)</p>
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According to Boyle's Law, what happens to pressure within the lungs as volume decreases?

<p>Pressure increases (D)</p>
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Which of the following lung volumes is NOT directly measured by spirometry?

<p>Residual Volume (RV) (A)</p>
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What is the primary function of surfactant in the lungs?

<p>Reduce surface tension in alveoli (A)</p>
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Which of the following is considered an obstructive lung disease?

<p>Asthma (D)</p>
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Which of the following parameters is typically measured in arterial blood gas analysis?

<p>Oxygen (A)</p>
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How does the Bohr effect influence hemoglobin's affinity for oxygen?

<p>Increases affinity with increased pH (B)</p>
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Where are the central chemoreceptors primarily located, and what substance do they detect?

<p>Medulla; CO2 (C)</p>
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Which of the following is a primary function of the digestive system?

<p>Breakdown and absorption of nutrients (D)</p>
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Which of the following is NOT a layer of the GI tract?

<p>Epidermis (B)</p>
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What digestive process involves mechanical and chemical breakdown of food?

<p>Digestion (C)</p>
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What is the migrating motor complex's (MMC) role in the digestive system?

<p>Cleans empty intestine (B)</p>
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What is the function of the Enteric Nervous System (ENS)?

<p>Local reflexes (C)</p>
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Which division of the nervous system modulates the Enteric Nervous System (ENS)?

<p>Central Nervous System (via ANS) (A)</p>
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Which brain structure is most associated with fine-tuning motor movements and maintaining balance?

<p>Cerebellum (D)</p>
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Damage to which brain area results in fluent aphasia, characterized by difficulty in language comprehension?

<p>Wernicke's Area (B)</p>
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Which type of sensory receptor is activated by physical deformation, such as pressure or vibration?

<p>Mechanoreceptors (A)</p>
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Which sensory receptor type is primarily involved in detecting tissue damage and pain?

<p>Nociceptors (D)</p>
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What is the correct sequence of events in signal transduction?

<p>Stimulus → Receptor → Threshold → Graded Potential → Action Potential (A)</p>
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What type of sensory adaptation is characterized by a slow or delayed response to stimulus?

<p>Tonic Adaptation (B)</p>
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Which of the following accurately represents the pathway of olfaction?

<p>Chemoreceptors → Olfactory Bulb → Olfactory Cortex (B)</p>
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Which of the following accurately represents the initial steps of the hearing pathway?

<p>Sound → Tympanic Membrane → Cochlea → Vestibulocochlear Nerve (C)</p>
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What is the correct sequence of structures involved in the visual pathway after light enters the eye?

<p>Retina → Optic Nerve → Thalamus → Visual Cortex (B)</p>
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Which of the following is a characteristic describing the sympathetic nervous system?

<p>Thoracolumbar Origin (A)</p>
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What class of hormones does cortisol belong to?

<p>Steroid Hormones (B)</p>
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Which of the following hormones is secreted by the posterior pituitary gland?

<p>Oxytocin (A)</p>
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What is the process called when an end hormone inhibits the hypothalamus or pituitary gland?

<p>Long-loop Feedback (B)</p>
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Which of the following exemplifies a direct physiological feedback loop?

<p>Both A and B (B)</p>
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What is the correct sequence of events in hemostasis?

<p>Vasoconstriction → Platelet Plug → Coagulation → Fibrinolysis (D)</p>
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Which component of the heart's electrical conduction system directly precedes the Purkinje fibers?

<p>Bundle of His (B)</p>
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Which component of the heart’s electrical system has the slowest velocity?

<p>AV node (D)</p>
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An ECG measures the electrical activity of the heart: which phase represents ventricular repolarization?

<p>T wave (D)</p>
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What is the influence of parasympathetic autonomic control on heart rate?

<p>Decreases Heart Rate (C)</p>
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Which sequence accurately depicts the flow of blood through vessels leaving the heart?

<p>Arteries → Arterioles → Capillaries → Venules (B)</p>
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How is Mean Arterial Pressure (MAP) calculated, given Diastolic Pressure (DP) and Pulse Pressure (PP)?

<p>$MAP = DP + (PP \times 1/3)$ (A)</p>
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Which physiological parameter is primarily regulated by the baroreceptor reflex?

<p>Blood Pressure (D)</p>
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Which of the following is a crucial function of the respiratory system?

<p>Gas Exchange (D)</p>
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Boyle's Law describes the relationship between pressure and volume; if the volume of the lungs decreases, what happens to the pressure within the lungs?

<p>Pressure Increases (D)</p>
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Which of the following properties of hemoglobin is affected by the Bohr effect?

<p>Affinity for Oxygen (D)</p>
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Where are the central chemoreceptors located, and what is the primary substance they detect to regulate respiration?

<p>Medulla; Carbon Dioxide (D)</p>
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Which of the following characteristics differentiates obstructive lung diseases from restrictive lung diseases?

<p>Increased Airway Resistance (B)</p>
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What is the major role of surfactant in the lungs?

<p>Reducing Surface Tension in Alveoli (A)</p>
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The upper respiratory tract consists of the

<p>Nose, and pharynx (C)</p>
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Which layer of the GI tract is responsible for secretion of enzymes, acids, and bile?

<p>Mucosa (B)</p>
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What is the term for the motility pattern of the digestive system that cleans any empty intestine?

<p>Migrating Motor Complex (C)</p>
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What describes mechanical and chemical digestion?

<p>Digestion (B)</p>
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Which division of the nervous system directly innervates the Enteric Nervous System (ENS)?

<p>Autonomic Nervous System (ANS) (C)</p>
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What type of hormone receptor is typically found on the cell membrane?

<p>Peptide (B)</p>
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What is the functional significance of the adrenal medulla secreting epinephrine into the bloodstream?

<p>Mimics and prolongs the effects of sympathetic nervous system activation. (A)</p>
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Upon administration of a novel drug, it's noted that the patient's blood pressure decreases. Further investigation reveals that this drug specifically increases the production of nitric oxide (NO) in vascular smooth muscle cells. Which mechanism best explains this drug's hypotensive effect?

<p>NO acts as a paracrine signal, causing vasodilation and reducing peripheral resistance. (C)</p>
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If an individual has a tidal volume of 500 mL, a respiratory rate of 12 breaths per minute, and a dead space volume of 150 mL, what is their alveolar ventilation?

<p>4.2 L/min (B)</p>
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Flashcards

Medulla

Controls respiration and heart rate.

Pons

Relays signals and controls breathing.

Midbrain

Deals with visual and auditory reflexes.

Cerebellum

Fine-tunes movement, posture, and balance.

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Thalamus

Relay station for sensory input.

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Hypothalamus

Regulates homeostasis, hormones, hunger, and thirst.

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Basal Ganglia

Motor planning; works with the cerebellum.

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Limbic System

Deals with emotion and memory.

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Wernicke's Area

Language comprehension area; damage results in fluent aphasia.

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Broca's Area

Speech production area; damage results in non-fluent aphasia.

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Mechanoreceptors

Sensory receptors that respond to mechanical pressure or distortion.

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Thermoreceptors

Sensory receptors that respond to temperature changes.

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Photoreceptors

Sensory receptors that respond to light.

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Chemoreceptors

Sensory receptors that respond to chemicals.

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Nociceptors

Sensory receptors that respond to pain.

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Signal Transduction

The process of converting a stimulus into an electrical signal.

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Adaptation

The process by which sensory receptors become less sensitive to a constant stimulus.

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Tonic Adaptation

Slow to adapt to a stimulus.

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Phasic Adaptation

Rapidly adapt to a stimulus.

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Olfaction

The sense of smell; involves chemoreceptors in the olfactory system.

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Hearing

The sense of hearing; involves the ear and vestibulocochlear nerve.

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Vision

The sense of sight; involves light, retina, and visual cortex.

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Sympathetic Nervous System

Thoracolumbar; short preganglionic, long postganglionic; uses NE.

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Parasympathetic Nervous System

Craniosacral; long preganglionic; uses ACh.

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Adrenal Medulla

Secretes epinephrine (like sympathetic ganglion).

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Somatic Motor Division

Direct control of skeletal muscle (uses ACh).

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Hormone classes

Peptides (e.g., insulin), Steroids (e.g., cortisol), Amines (e.g., epinephrine).

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Anterior Pituitary Gland Hormones

ACTH, TSH, GH, LH, FSH, Prolactin.

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Posterior Pituitary Gland Hormones

Oxytocin, ADH.

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Long-loop Feedback

End hormone inhibits hypothalamus/pituitary.

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Plasma

Water, proteins (albumin, globulin, fibrinogen), nutrients, hormones.

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Formed Elements

RBCs, WBCs, platelets.

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Hemoglobin

4 subunits; binds O2; iron-dependent.

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Blood Pathologies

Anemia, polycythemia.

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Hemostasis

Vasoconstriction → platelet plug → coagulation → fibrinolysis

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Heart Anatomy

4 chambers, valves (AV, semilunar).

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Heart's Electrical System

SA node → AV node → Bundle of His → Purkinje fibers

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ECG Waves

P wave = atrial depolarization, QRS = ventricular depolarization, T wave = repolarization

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Cardiac Output

CO = HR × SV

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Autonomic Control of Heart Rate

Sympathetic ↑ HR; Parasympathetic ↓ HR

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Adrenal Medulla Function

Endocrine glands secrete epinephrine directly into the bloodstream, similar to a sympathetic ganglion response.

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Direct physiological feedback

Insulin and PTH directly regulate physiological parameters without hypothalamic involvement.

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Blood Vessel Order

Arteries carry blood away from the heart leading to smaller arterioles, then to capillaries for exchange, then back to the heart via venules and veins.

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Cardiac Output Equation

CO (cardiac output) is determined by the product of HR (heart rate) and SV (stroke volume).

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Baroreceptor Reflex

Changes in blood pressure are detected by baroreceptors in the carotid and aortic bodies, triggering regulatory reflexes.

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Respiratory Functions

The exchange of gases, pH regulation, vocalization, and protection.

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Upper Respiratory Tract

Nose and pharynx.

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Lower Respiratory Tract

Larynx, trachea, bronchi, and lungs.

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Breathing Mechanics

Volume decrease leads to pressure increase. Inspiration occurs when the diaphragm contracts. Expiration is passive.

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Lung Volumes

TV, IRV, ERV, VC, TLC.

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Surfactant Function

Reduces surface tension in the alveoli, preventing collapse.

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Obstructive Lung Diseases

Asthma, COPD.

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Restrictive Lung Disease

Pulmonary fibrosis.

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Arterial Blood Parameters

O2, CO2 and pH.

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Gas Exchange Influencers

Gradient, surface area, thickness, and diffusion distance.

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Hemoglobin Properties

Hemoglobin binds O2 cooperatively and is affected by pH, CO2, and temperature

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Respiratory Control Centers

Medulla controls basic rhythm, pons fine-tunes, and chemoreceptors sense CO2, O2.

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Primary Digestive Function

Breaks down food and absorb nutrients.

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GI Tract Layers

Mucosa, submucosa, muscularis, and serosa.

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Digestive Secretions

Enzymes, acids, and bile.

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Digestion Type

Mechanical and chemical breakdown of food.

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Absorption

Nutrient uptake.

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Motility

Movement (peristalsis and segmentation).

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Peristalsis

Propulsive movement.

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Segmentation

Mixing movement.

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Migrating Motor Complex

Cleans empty intestine.

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ENS Control

Local reflexes.

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CNS Role in Digestion

Modulates ENS.

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Study Notes

  • Study notes for Exams 5, 6, & 7

CNS Structures & Functions

  • Brainstem is comprised of the medulla, pons, and midbrain
  • Medulla controls respiration and heart rate
  • Pons relays signals and controls breathing
  • Midbrain handles visual/auditory reflexes
  • Cerebellum fine-tunes posture, movement, and balance
  • Thalamus is a relay station for sensory input
  • Hypothalamus regulates homeostasis, hormones, hunger, and thirst
  • Basal Ganglia handles motor planning and functions with the cerebellum
  • Limbic System handles emotion and memory
  • Amygdala is for emotion, hippocampus is for memory
  • Wernicke's Area is for language comprehension, damage results in fluent aphasia
  • Broca's Area is for speech production, damage results in non-fluent aphasia

Sensory Systems

  • Receptors include mechanoreceptors, thermoreceptors, photoreceptors, chemoreceptors, and nociceptors
  • Signal Transduction transforms stimulus to receptor, then to threshold, graded potential, and action potential
  • Adaptation is how receptors adjust to prolonged stimulation
  • Tonic receptors are slow to adapt
  • Phasic receptors are rapid to adapt
  • Olfaction uses chemoreceptors that go to the olfactory bulb then olfactory cortex
  • Hearing is sound that travels to the tympanic membrane, cochlea, then to the vestibulocochlear nerve, and finally the brain
  • Vision begins with light to the retina, optic nerve, thalamus, then the visual cortex

Autonomic and Somatic Systems

  • Sympathetic nervous system (fight/flight) originates in the thoracolumbar region, has short preganglionic fibers and long postganglionic fibers, and uses norepinephrine (NE)
  • Parasympathetic nervous system (rest/digest) originates in the craniosacral region, has long preganglionic fibers, and uses acetylcholine (ACh)
  • Adrenal Medulla secretes epinephrine
  • Somatic Motor Division provides direct control of skeletal muscle and uses acetylcholine (ACh)

Hormones

  • Hormone Classes include peptides (e.g., insulin), steroids (e.g., cortisol), and amines (e.g., epinephrine)
  • Peptide receptors are located on the cell membrane
  • Steroid receptors are located intracellular/nuclear
  • Anterior Pituitary Gland produces ACTH, TSH, GH, LH, FSH, and Prolactin
  • Posterior Pituitary Gland produces Oxytocin and ADH
  • Long-loop Feedback involves the end hormone inhibiting the hypothalamus/pituitary
  • Insulin and PTH show direct physiological feedback

Cardiovascular System

  • Plasma is composed of water, proteins (albumin, globulin, fibrinogen), nutrients, and hormones
  • Formed Elements are red blood cells (RBCs), white blood cells (WBCs), and platelets
  • Hemoglobin has 4 subunits and binds to oxygen
  • Pathologies include anemia and polycythemia
  • Hemostasis is the process of vasoconstriction leading to platelet plug formation, coagulation, and fibrinolysis
  • Heart anatomy consists of 4 chambers and valves (AV, semilunar)
  • Electrical System of the heart includes the SA node, AV node, Bundle of His, and Purkinje fibers
  • ECG records the heart's electrical activity
    • P wave represents atrial depolarization
    • QRS complex represents ventricular depolarization
    • T wave represents repolarization
  • Cardiac Output (CO) is calculated as Heart Rate (HR) × Stroke Volume (SV)
  • Autonomic Control affects HR
    • Sympathetic stimulation increases HR
    • Parasympathetic stimulation decreases HR
  • Blood Vessels flow from arteries to arterioles, then to capillaries, venules, and finally veins
  • Blood Pressure (BP) Regulation is Cardiac Output × Resistance
  • Mean Arterial Pressure (MAP) is Diastolic Pressure + 1/3(Pulse Pressure)
  • Autoregulation involves myogenic and paracrine (NO, prostaglandins) mechanisms
  • Capillary Exchange involves filtration vs. absorption (Starling forces)
  • Baroreceptor Reflex responds to BP changes and is found in carotid/aortic bodies

Respiratory Physiology

  • Functions of the respiratory system include gas exchange, pH regulation, vocalization, and protection
  • Upper tract anatomy includes the nose and pharynx
  • Lower tract anatomy includes the larynx, trachea, bronchi, and lungs
  • Breathing Mechanics follow Boyle's Law
    • Decreased volume leads to increased pressure -Inspiration requires diaphragm contraction
    • Expiration is passive
  • Lung Volumes include Tidal Volume (TV), Inspiratory Reserve Volume (IRV), Expiratory Reserve Volume (ERV), Vital Capacity (VC), and Total Lung Capacity (TLC)
  • Surfactant reduces surface tension in alveoli and prevents collapse
  • Obstructive diseases include asthma and COPD
  • Restrictive diseases include pulmonary fibrosis

Gas Exchange & Control

  • Arterial Blood Parameters measured include oxygen (O2), carbon dioxide (CO2), and pH
  • Gas Exchange Influencers are gradient, surface area, thickness, and diffusion distance
  • Hemoglobin binds O2 cooperatively and is affected by pH (Bohr effect), CO2, and temperature
  • Control Centers for respiration
    • Medulla controls basic rhythm
    • Pons fine-tunes respiration
    • Chemoreceptors, central (CO2) and peripheral (O2, pH), provide sensory input

Digestion

  • Primary Function is the breakdown and absorption of nutrients
  • GI Tract Layers are mucosa, submucosa, muscularis, and serosa
  • Processes include secretion of enzymes, acids, and bile, mechanical/chemical digestion, nutrient absorption, and motility
  • Motility Patterns
    • Peristalsis is propulsive
    • Segmentation is mixing
    • Migrating Motor Complex cleans the empty intestine
  • Nervous Control
    • ENS (Enteric Nervous System) uses local reflexes
    • CNS (via ANS) modulates the ENS

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