20 Questions
What is one of the uses of CNS drugs mentioned in the text?
Treatment for depression and epilepsy
What is the approximate number of neurons in the human brain?
100 billion neurons
What is the effect of many drugs that take weeks to develop?
Long-term changes in the brain
How are neurotransmitter systems interconnected?
Modifying one is likely to affect the others
What is the role of dopamine receptor antagonists in schizophrenia mentioned in the text?
The cellular effect of the drug may be known, but its relation to functional outcome may not be clear
What is the approximate number of synaptic connections in the human brain?
1 trillion
What is the effect of drugs of abuse on neurotransmitters GABA and glutamate?
They modulate other neurotransmitters
What is the role of some neurotransmitter receptors located presynaptically?
Enhance neurotransmitter release
Which neurotransmitter is actively packaged into vesicles by an amine transporter?
Acetylcholine
What is the primary target for the treatment of Alzheimer's disease?
Acetylcholinesterase
Which receptors are ligand-gated ion channel receptors for fast excitatory synaptic transmission?
Nicotinic receptors
Which cells in the brain project to the hippocampus and are important for learning and memory?
Cells in nucleus basalis
Which neurotransmitter's loss of neurons is mainly associated with Alzheimer's disease?
Acetylcholine
What is the role of cholinergic interneurons in the striatum in Parkinson's disease?
They oppose the effects of dopamine
Which characteristic features are associated with Alzheimer's disease?
Neuritic plaques and neurofibrillary tangles
Which drug acts as a positive allosteric modulator of nicotinic receptors?
Galantamine
Which cells in the brain project to the cortex and are important for arousal?
Cells in nucleus basalis
Which receptors are G-protein coupled receptors for slow excitatory or inhibitory synaptic transmission?
Muscarinic receptors
Which neurotransmitter's loss of neurons is mainly associated with Parkinson's disease?
Dopamine
Which drug is used to treat the symptoms of Alzheimer's disease by reducing enzymatic degradation of acetylcholine?
Rivastigmine
Test your knowledge of CNS drugs and neurotransmitters with this quiz. Explore the therapeutic, lifestyle, and abuse applications of CNS drugs, and delve into the complex mechanisms of action within the brain.
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