Clotting Cascade Overview

Quale substanzia activa la via intrinseca de coagulation?

Quale factor de coagulation es necessita pro activation del factor 10?

Quale effecto ha thrombin (IIa) in le cascada de coagulation?

Quale factor es assente in le hemophilia menos commun?

Quale organo es responsabile pro production de factores de coagulation?

Clotting Cascade

The intrinsic pathway begins with vessel damage, exposing collagen, initiating a cascade of reactions.
The extrinsic pathway begins with subendothelial cells or tissue damage, activating a separate cascade.
Exposed collagen triggers factor XII activation.
Factor XIIa activates factor XI, which then activates factor IX.
Factor IXa, with its cofactor, activates factor X.
Factor Xa, with its cofactor, converts prothrombin to thrombin.
Thrombin converts fibrinogen to fibrin, forming a clot.
Platelets are activated by thrombin and exposed collagen, contributing to clot formation.
The extrinsic pathway involves tissue factor (factor III), which activates factor VII.
Factor VIIa activates factor X, leading to thrombin formation and clot formation, similarly to the intrinsic pathway.
The liver produces clotting factors, requiring vitamin K.
Cofactors (e.g., phospholipid) enhance the efficiency of the clotting factors.
A positive feedback loop amplifies the clotting cascade.

Este quiz explora le cascada de coagulation, includente le vias intrinseca e extrinseca. Revisa como factores specific e cofactores interagisce pro formar un coagulo e le rol de trombina in iste processo. Testa tu comprehension del subjecte crucial pro le salud del sanguine.